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In 2022, a group of basic and clinical virologists, bioinformaticians, and evolutionary and structural biologists met in Oxford, UK, to develop a consensus on methodologies used to classify viruses. They concluded that virus taxonomy, which…

种群与进化 · 定量生物学 2023-09-26 Alexandr A. Ezhov

Keeping track of scientific challenges, advances and emerging directions is a fundamental part of research. However, researchers face a flood of papers that hinders discovery of important knowledge. In biomedicine, this directly impacts…

Preventing data exfiltration from computer systems typically depends on perimeter defences, but these are becoming increasingly fragile. Instead we suggest an approach in which each at-risk document is supplemented by many fake versions of…

密码学与安全 · 计算机科学 2018-09-14 David Skillicorn , Xiao Li , Karen Chen

Recommender systems have become an integral part of online services to help users locate specific information in a sea of data. However, existing studies show that some recommender systems are vulnerable to poisoning attacks, particularly…

The correlation and interactions among different biological entities comprise the biological system. Although already revealed interactions contribute to the understanding of different existing systems, researchers face many questions…

信息检索 · 计算机科学 2014-01-14 Md. Naseef-Ur-Rahman Chowdhury , Suvankar Paul , Kazi Zakia Sultana

In biology, there are several questions that translate to combinatorial search. For example, vesicle traffic systems that move cargo within eukaryotic cells have been proposed to exhibit several graph properties such as three connectivity.…

其他计算机科学 · 计算机科学 2018-04-17 Ashutosh Gupta , Ankit Shukla , Mandyam Srivas , Mukund Thattai

In the era of the internet and smart devices, the detection of malware has become crucial for system security. Malware authors increasingly employ obfuscation techniques to evade advanced security solutions, making it challenging to detect…

密码学与安全 · 计算机科学 2024-04-04 S M Rakib Hasan , Aakar Dhakal

This paper analyzes a simplified model of viral infection and evolution using the 'grand canonical ensemble' and formalisms from statistical mechanics and thermodynamics to enumerate all possible viruses and to derive thermodynamic…

种群与进化 · 定量生物学 2016-01-08 Barbara A. Jones , Justin Lessler , Simone Bianco , James H. Kaufman

Living organisms rely on molecular networks, such as gene circuits and signaling pathways, for information processing and robust decision-making in crowded, noisy environments. Recent advances show that interacting biomolecules…

In this work, a new concept called Vector Dissipation of Randomness (VDR) is developed and formalized. It describes the mechanism by which complex multicomponent systems transition from chaos to order through the filtering of random…

物理与社会 · 物理学 2025-03-25 Eldar Knar

The design of protocols to suppress the propagation of viral infections is an enduring enterprise, especially hindered by limited knowledge of the mechanisms through which extinction of infection propagation comes about. We here report on a…

种群与进化 · 定量生物学 2015-02-18 Jose A. Cuesta , Jacobo Aguirre , Jose A. Capitan , Susanna C. Manrubia

We present a novel system that automatically extracts and generates informative and descriptive sentences from the biomedical corpus and facilitates the efficient search for relational knowledge. Unlike previous search engines or…

计算与语言 · 计算机科学 2023-10-19 Kerui Zhu , Jie Huang , Kevin Chen-Chuan Chang

We review recent progress made in analyzing the spread of viruses and bugs in the internet. We describe how the use of a model that takes into account the complex inhomogeneity of the internet and its self organizing characteristics can…

物理与社会 · 物理学 2011-06-07 Swarbhanu Chatterjee

We propose an approach of open-ended evolution via the simulation of swarm dynamics. In nature, swarms possess remarkable properties, which allow many organisms, from swarming bacteria to ants and flocking birds, to form higher-order…

多智能体系统 · 计算机科学 2019-03-21 Olaf Witkowski , Takashi Ikegami

Bio-inspired paradigms are proving to be useful in analyzing propagation and dissemination of information in networks. In this paper we explore the use of multi-type branching processes to analyse viral properties of content in a social…

概率论 · 数学 2020-01-01 Ranbir Dhounchak , Veeraruna Kavitha , Eitan Altman

It is well known that anti-malware scanners depend on malware signatures to identify malware. However, even minor modifications to malware code structure results in a change in the malware signature thus enabling the variant to evade…

密码学与安全 · 计算机科学 2025-05-27 Ritwik Murali , C Shunmuga Velayutham

In this research paper, our intent is to outline different types of malware, their means of operation, and how they are detected in order to protect yourself against such attacks. Varied permission, and limited technical resources mean that…

密码学与安全 · 计算机科学 2022-12-26 Sebastian Grochola , Andrew Milliner

One strategy for winning a coevolutionary struggle is to evolve rapidly. Most of the literature on host-pathogen coevolution focuses on this phenomenon, and looks for consequent evidence of coevolutionary arms races. An alternative…

种群与进化 · 定量生物学 2012-11-14 Erick Chastain , Rustom Antia , Carl T. Bergstrom

Pangenome variation graphs (PVGs) allow for the representation of genetic diversity in a more nuanced way than traditional reference-based approaches. Here we focus on how PVGs are a powerful tool for studying genetic variation in viruses,…

基因组学 · 定量生物学 2025-06-18 Tim Downing

To extract essential information from complex data, computer scientists have been developing machine learning models that learn low-dimensional representation mode. From such advances in machine learning research, not only computer…

人工智能 · 计算机科学 2024-06-18 Akira Matsui , Emilio Ferrara