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Terahertz (THz)-based electron manipulation has recently been shown to hold tremendous promise as a technology for manipulating and driving the next-generation of compact ultrafast electron sources. Here, we demonstrate an ultrafast…

Due to the non-ionizing property, researchers have chosen to investigate terahertz radiation (THz) Imaging instrumentation for Bio-Sensing applications. The present work is to design and fabricate a near field lens that can focus guided…

光学 · 物理学 2017-04-25 P. Babu , S. Ganganagunta

Strong-field mid-infrared pump--terahertz (THz) probe spectroscopy has been proven as a powerful tool for light control of different orders in strongly correlated materials. We report the construction of an ultrafast broadband infrared…

仪器与探测器 · 物理学 2017-10-10 S. J. Zhang , Z. X. Wang , T. Dong , N. L. Wang

The microscopic origins of terahertz (THz) vibrational modes in biological systems are an active and open area of current research. Recent experiments [Physical Review X 8, 031061 (2018)] have revealed the presence of a pronounced mode at…

生物物理 · 物理学 2022-10-28 Khatereh Azizi , Matteo Gori , Uriel Morzan , Ali Hassanali , Philip Kurian

The electric field of biological membranes has long been treated as a one-dimensional quantity, defined solely by the component normal to the bilayer (E_VERT). Here, we present a bioelectronic platform that enables controlled generation of…

We present a novel experimental setup in which magnetic and optical tweezers are combined for torque and force transduction onto single filamentous molecules in a transverse configuration to allow simultaneous mechanical measurement and…

生物大分子 · 定量生物学 2015-06-24 Zhaokun Zhou , Helen Miller , Adam J. M. Wollman , Mark C. Leake

Photoelectrochemical (PEC) biosensors exhibit significant potential for biomolecule detection due to their high sensitivity and low background noise. However, their performance is severely constrained by the rapid recombination of…

Investigating the dynamics of single biomolecules is essential for unlocking new frontiers in biophysics and medicine. Here, we present a transformative approach using metamaterial optical tweezers to trap and study individual urease…

The advent of ultrafast science with pulsed electron beams raised the need in controlling the temporal features of the electron pulses. One promising suggestion is the nano-selective quantum optics with multi-electrons, which scales…

光学 · 物理学 2023-08-07 Yarden Mazor , Ofer Kfir

Compact terahertz (THz) functional devices are greatly sought after for high-speed wireless communication, biochemical sensing, and non-destructive inspection. However, conventional devices to generate and guide THz waves are afflicted with…

The efficient amplification and lasing of electromagnetic radiation at terahertz (THz) frequencies is a non-trivial task achieved mainly by quantum cascade laser configurations with limited tunability and narrowband functionality. There is…

光学 · 物理学 2018-11-30 Tianjing Guo , Liang Zhu , Pai-Yen Chen , Christos Argyropoulos

Environmental transmission electron microscopy (E-TEM) enables direct observation of nanoscale chemical processes crucial for catalysis and materials design. However, the high-energy electron probe can dramatically alter reaction pathways…

Single-enzyme catalysis offers a promising approach for unravelling the dynamic behaviour of individual enzymes as they undergo a reaction, revealing the complex heterogeneity that is lost in the averaged ensembles. Here we demonstrate…

Proteins can be regarded as thermal nanosensors in an intra-body network. Upon being stimulated by Terahertz (THz) frequencies that match their vibrational modes, protein molecules experience resonant absorption and dissipate their energy…

分子网络 · 定量生物学 2024-07-01 Hadeel Elayan , Samar Elmaadawy , Andrew W. Eckford , Raviraj Adve , Josep Jornet

We show that coherently driven atomic or molecular media potentially yield strong controllable short pulses of THz radiation. The method is based on excitation of maximal quantum coherence in a gas medium by optical pulses and coherent…

量子物理 · 物理学 2007-05-23 Nikolai G. Kalugin , Yuri V. Rostovtsev , Marlan O. Scully

We report that a cell-sized water droplet (CWD) with a diameter of several tens of microns can serve as a micro-biochemical reactor. Since the droplet inner surface is covered by a phospholipid layer, it provides an environment similar to…

生物物理 · 物理学 2007-05-23 Masahiko Hase , Ayako Yamada , Tsutomu Hamada , Kenichi Yoshikawa

We analyze the operation of a resonant detector of terahertz (THz) radiation based on a two-dimensional electron gas (2DEG) channel with split gates. The side gates are used for the excitation of plasma oscillations by incoming THz…

其他凝聚态物理 · 物理学 2009-11-13 V. Ryzhii , A. Satou , T. Otsuji , M. S. Shur

Nonlinear terahertz (THz) spectroscopy relies on the interaction of matter with few-cycle THz pulses of electric field amplitudes up to megavolts/centimeter (MV/cm). In condensed-phase molecular systems, both resonant interactions with…

化学物理 · 物理学 2021-12-08 Klaus Reimann , Michael Woerner , Thomas Elsaesser

The zymase activity of the yeast Saccharomyces Cerevisiae is sensitive to environmental parameters and is therefore used as a microbiological sensor for water quality assessment, ecotoxicological characterization or environmental…

Fingerprint spectral response of several materials with terahertz electromagnetic radiation indicates that terahertz technology is an effective tool for sensing applications. However, sensing few nanometer thin-film of dielectrics with much…