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We analyze the effects of spatially extended periodic forcing on the dynamics of one-dimensional excitation waves. Entrainment of unstable primary waves has been studied numerically for different amplitudes and frequencies of additional…

混沌动力学 · 物理学 2011-06-03 Joseph M. Starobin , Vivek Varadarajan

We study the dynamics of a simple adaptive system in the presence of noise and periodic damping. The system is composed by two paths connecting a source and a sink, the dynamics is governed by equations that usually describe food search of…

统计力学 · 物理学 2021-12-23 Frederic Folz , Kurt Mehlhorn , Giovanna Morigi

The spontaneous generation of electrical activity underpins a number of essential physiological processes, and is observed even in tissues where specialized pacemaker cells have not been identified. The emergence of periodic oscillations in…

适应与自组织系统 · 物理学 2022-02-01 Ria Ghosh , Shakti N. Menon

Influence of mesoscopic channel noise on excitable dynamics of living cells became a hot subject within the last decade, and the traditional biophysical models of neuronal dynamics such as Hodgkin-Huxley model have been generalized to…

神经元与认知 · 定量生物学 2014-09-24 Igor Goychuk

Being an example for a relaxation oscillator, the FitzHugh-Nagumo model has been widely employed for describing the generation of action potentials. In this paper, we begin with a biological interpretation of what the subsequent…

数值分析 · 数学 2025-01-31 Burcu Gürbüz , Aytül Gökçe , Mahmut Modanlı

We present a new model for the dynamics of the presynaptic intracellular calcium concentration in neurons evoked by various stimulation protocols. The aim of the model is twofold: We want to discuss the calcium transients during and after…

生物物理 · 物理学 2007-05-23 Michael Meyer-Hermann , Frido Erler , Gerhard Soff

We analyze an inhomogeneous system of coupled reaction-diffusion equations representing the dynamics of gene expression during differentiation of nerve cells. The outcome of this developmental phase is the formation of distinct functional…

偏微分方程分析 · 数学 2014-08-28 Benoit Perthame , Cristobal Quiñinao , Jonathan Touboul

We have analyzed the interplay between noise and periodic modulations in a mean field model of a neural excitable medium. To this purpose, we have considered two types of modulations; namely, variations of the resistance and oscillations of…

统计力学 · 物理学 2016-08-15 J. M. G. Vilar , R. V. Solé , J. M. Rubí

The analysis of noise-induced escape in populations of bistable elements is challenging, because nonlinearity, coupling, and noise all play essential roles. We show that the interplay of these three factors yields three qualitatively…

适应与自组织系统 · 物理学 2026-03-06 Hidemasa Ishii , Hiroshi Kori

We propose a simple discrete stochastic model for calcium dynamics in living cells. Specifically, the calcium concentration distribution is assumed to give rise to a set of probabilities for the opening/closing of channels which release…

patt-sol · 物理学 2009-10-31 Markus Baer , Martin Falcke , Herbert Levine , Lev S. Tsimring

We review theoretical models of individual motility as well as collective dynamics and pattern formation of active particles. We focus on simple models of active dynamics with a particular emphasis on nonlinear and stochastic dynamics of…

其他凝聚态物理 · 物理学 2015-06-04 Pawel Romanczuk , Markus Bär , Werner Ebeling , Benjamin Lindner , Lutz Schimansky-Geier

The present study investigates the spatio-temporal variability in the dynamics of self-sustained supersonic reaction waves propagating through an excitable medium. The model is an extension of Fickett's detonation model with a state…

流体动力学 · 物理学 2013-05-29 Matei I. Radulescu , Justin Tang

Coordinated responses to environmental stimuli are critical for multicellular organisms. To overcome the obstacles of cell-to-cell heterogeneity and noisy signaling dynamics within individual cells, cells must effectively exchange…

生物物理 · 物理学 2022-10-12 Guanyu Li , Ryan LeFebre , Alia Starman , Patrick Chappell , Andrew Mugler , Bo Sun

At functional scales, cortical behavior results from the complex interplay of a large number of excitable cells operating in noisy environments. Such systems resist to mathematical analysis, and computational neurosciences have largely…

神经元与认知 · 定量生物学 2014-03-05 Mathieu Galtier , Jonathan Touboul

We analyze a model of mutually-propelled filaments suspended in a two-dimensional solvent. The system undergoes a mean-field isotropic-nematic transition for large enough filament concentrations and the nematic order parameter is allowed to…

软凝聚态物质 · 物理学 2011-05-26 L. Giomi , L. Mahadevan , B. Chakraborty , M. F. Hagan

A large number of biological systems - from bacteria to sheep - can be described as ensembles of self-propelled agents (active particles) with a complex internal dynamic that controls the agent's behavior: resting, moving slow, moving fast,…

生物物理 · 物理学 2021-09-03 L. Gómez-Nava , T. Goudon , F. Peruani

The dynamic range measures the capacity of a system to discriminate the intensity of an external stimulus. Such an ability is fundamental for living beings to survive: to leverage resources and to avoid danger. Consequently, the larger is…

神经元与认知 · 定量生物学 2012-05-02 Leonardo L. Gollo , Claudio Mirasso , Víctor M. Eguíluz

We propose a neural network model of multi-neuron interacting system that simulates neurons to interact each other through the surroundings of neuronal cell bodies. We physically model the neuronal cell surroundings, include the dendrites,…

神经元与认知 · 定量生物学 2021-07-05 Yu-Juan Sun , Wei-Min Zhang

We model the spatiotemporal dynamics of cellular protein concentrations near membranes composed of different lipids using a three-variable continuum model for membrane-bound protein, cytosolic protein, and the local composition of a binary…

软凝聚态物质 · 物理学 2026-03-26 Benjamin Winkler , Sergio Alonso , Markus Bär

Many extended chemical and biological systems self-organise into complex patterns that drive the medium behaviour in a non-linear fashion. An important class of such systems are excitable media, including neural and cardiac tissues. In…

其他定量生物学 · 定量生物学 2024-09-09 Louise Arno , Desmond Kabus , Hans Dierckx