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We describe the simulation method of modelling the population evolution using Monte Carlo based on the Penna model. Individuals in the populations are represented by their diploid genomes. Genes expressed after the minimum reproduction age…

基因组学 · 定量生物学 2009-01-13 Agnieszka Laszkiewicz , Przemyslaw Biecek , Katarzyna Bonkowska , Stanislaw Cebrat

The population in the sexual Penna ageing model is first separated into several reproductively isolated groups. Then, after equilibration, sexual mixing between the groups is allowed. We study the changes in the population size due to this…

种群与进化 · 定量生物学 2009-11-13 K. Bonkowska , M. Kula , S. Cebrat , D. Stauffer

A deterministic model of an age-structured population with genetics analogous to the discrete time Penna model of genetic evolution is constructed on the basis of the Lotka-Volterra scheme. It is shown that if, as in the Penna model,…

种群与进化 · 定量生物学 2007-05-23 Miroslaw R. Dudek

The bit-string Penna Model is used to simulate the competition between an asexual parthenogenetic and a sexual population sharing the same environment. A new-born of either population can mutate and become a part of the other with some…

统计力学 · 物理学 2009-10-31 J. S. Sa' Martins

In simulations of sexual reproduction with diploid individuals, we introduce that female haploid gametes recognize one specific allele of the genomes as a marker of the male haploid gametes. They fuse to zygotes preferrably with male…

种群与进化 · 定量生物学 2009-11-13 S. Cebrat , D. Stauffer

The sexual version of the Penna model of biological ageing, simulated since 1996, is compared here with alternative forms of reproduction as well as with models not involving ageing. In particular we want to check how sexual forms of life…

We have used the sexual Penna ageing model to show that the relation between dominance and recessiveness could be a force which optimizes the genome size. While the possibility of complementation of the damaged allele by its functional…

种群与进化 · 定量生物学 2007-05-23 Diana Garncarz , Stanislaw Cebrat , Dietrich Stauffer , Klaus Blindert

Intragenomic recombination (crossover) is a very important evolutionary mechanism. The crossover events are not evenly distributed along the natural chromosomes. Monte Carlo simulations revealed that frequency of recombinations decides…

基因组学 · 定量生物学 2009-01-13 Wojciech Waga , Marta Zawierta , Jakub Kowalski , Stanislaw Cebrat

Using Monte Carlo model of biological evolution we have discovered that populations can switch between two different strategies of their genomes' evolution; Darwinian purifying selection and complementing the haplotypes. The first one is…

种群与进化 · 定量生物学 2009-11-13 Marta Zawierta , Wojciech Waga , Dorota Mackiewicz , Przemyslaw Biecek , Stanislaw Cebrat

We discuss two different ways of chromosomes' and genomes' evolution. Purifying selection dominates in large panmictic populations, where Mendelian law of independent gene assortment is valid. If the populations are small, recombination…

种群与进化 · 定量生物学 2010-07-21 Stanislaw Cebrat , Dietrich Stauffer , Wojciech Waga

We have simulated demographic changes in the human population using the Penna microscopic model, based on the simple Monte Carlo method. The results of simulations have shown that during a few generations changes in the genetic pool of a…

统计力学 · 物理学 2007-05-23 A. Laszkiewicz , Sz. Szymczak , S. Cebrat

Modifying the Redfield model of sexual reproduction and the Penna model of biological aging, we compare reproduction with and without recombination in age-structured populations. In contrast to Redfield and in agreement with Bernardes we…

Using a lattice model based on Monte Carlo simulations, we study the role of the reproduction pattern on the fate of an evolving population. Each individual is under the selection pressure from the environment and random mutations. The…

统计力学 · 物理学 2009-11-10 Mingfeng He , Hongbo Ruan , Changliang Yu , Lei Yao

We present some results of simulations of population growth and evolution, using the standard asexual Penna model, with individuals characterized by a string of bits representing a genome containing some possible mutations. After about…

种群与进化 · 定量生物学 2009-11-11 Mikolaj Sitarz , Andrzej Z. Maksymowicz

We modify the Penna Model for biological aging, which is based on the mutation-accumulation theory, in order to verify if there would be any evolutionary advantage of triploid over diploid organisms. We show that this is not the case, and…

统计力学 · 物理学 2007-05-23 A. O. Sousa , S. Moss de Oliveira , J. S. Sa Martins

In sexual population, recombination reshuffles genetic variation and produces novel combinations of existing alleles, while selection amplifies the fittest genotypes in the population. If recombination is more rapid than selection,…

种群与进化 · 定量生物学 2015-06-05 Richard A. Neher , Marija Vucelja , Marc Mézard , Boris I. Shraiman

We updated the agent based Monte Carlo code HERITAGE that simulates human evolution within restrictive environments such as interstellar, sub-light speed spacecraft in order to include the effects of population genetics. We incorporated a…

科普物理 · 物理学 2021-02-03 F. Marin , C. Beluffi , F. Fischer

This paper studies the mutation-selection balance in three simplified replication models. The first model considers a population of organisms replicating via the production of asexual spores. The second model considers a sexually…

种群与进化 · 定量生物学 2009-11-13 Emmanuel Tannenbaum

We generalize the standard Penna bit-string model of biological ageing by assuming that each deleterious mutation diminishes the survival probability in every time interval by a small percentage. This effect is added to the usual lethal but…

统计力学 · 物理学 2015-06-24 J. S. Sá Martins , D. Stauffer

Modelling genetic phenomena affecting biological traits is important for the development of agriculture as it allows breeders to predict the potential of breeding for certain traits. One such phenomenon is heterosis or hybrid vigor:…

种群与进化 · 定量生物学 2015-03-24 Peter M. F. Emmrich , Hannah E. Roberts , Vera Pancaldi
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