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Low-dimensional descriptions of neural network dynamics are an effective tool for bridging different scales of organization of brain structure and function. Recent advances in deriving mean-field descriptions for networks of coupled…

神经元与认知 · 定量生物学 2021-11-03 Richard Gast , Thomas R. Knösche , Helmut Schmidt

A Self Consistent Field Theory description of equilibrium, but non uniform, configurations adopted by semi flexible liquid crystal molecules is presented. Two cases are considered, isotropic-nematic phase boundaries, and topological defects…

软凝聚态物质 · 物理学 2025-03-03 Longyu Qing , Jorge Viñals

We develop a mesoscopic model to study the plastic behavior of an amorphous material under cyclic loading. The model is depinning-like and driven by a disordered thresholds dynamics which are coupled by long-range elastic interactions. We…

软凝聚态物质 · 物理学 2023-08-07 Dheeraj Kumar , Sylvain Patinet , Craig E. Maloney , Ido Regev , Damien Vandembroucq , Muhittin Mungan

This letter investigates the robust beamforming design for a near-field secure integrated sensing and communication (ISAC) system with multiple communication users (CUs) and targets, as well as multiple eavesdroppers. Taking into account…

信息论 · 计算机科学 2025-07-18 Ziqiang CHen , Feng Wang , Guojun Han , Xin Wang , Vincent K. N. Lau

Message passing between components of a distributed physical system is non-instantaneous and contributes to determine the time scales of the emerging collective dynamics like an effective inertia. In biological neuron networks this inertia…

神经元与认知 · 定量生物学 2019-10-15 Matteo Biggio , Marco Storace , Maurizio Mattia

We develop a spatially explicit biophysical model of the hippocampal CA3-CA1 presynaptic bouton to study local calcium dynamics leading to vesicle fusion. A kinetic model with two calcium sensors is formulated specifically for the CA3-CA1…

神经元与认知 · 定量生物学 2010-05-02 Suhita Nadkarni , Thomas Bartol , Terrence Sejnowski , Herbert Levine

We study an abstracted model of neuronal activity via numerical simulation, and report spatiotemporal pattern formation and critical like dynamics. A population of pulse coupled, discretised, relaxation oscillators is simulated over…

神经元与认知 · 定量生物学 2019-04-24 Dionysios Georgiadis , Didier Sornette

The behavior of active matter under confinement poses significant challenges due to the intricate coupling between dynamics near boundaries and those in the bulk. A defining feature of active matter systems is that a substantial portion of…

偏微分方程分析 · 数学 2025-08-25 Leonid Berlyand , Spencer Dang , Pierre-Emmanuel Jabin , Mykhailo Potomkin

The collective dynamics of excitatory pulse coupled neural networks with spike timing dependent plasticity (STDP) is studied. Depending on the model parameters stationary states characterized by High or Low Synchronization can be observed.…

无序系统与神经网络 · 物理学 2015-04-14 Kaare Mikkelsen , Alberto Imparato , Alessandro Torcini

Construction of a scaffold structure that supports a desired motif, conferring protein function, shows promise for the design of vaccines and enzymes. But a general solution to this motif-scaffolding problem remains open. Current…

生物大分子 · 定量生物学 2023-03-21 Brian L. Trippe , Jason Yim , Doug Tischer , David Baker , Tamara Broderick , Regina Barzilay , Tommi Jaakkola

Membrane receptors for neuromodulators (NM) are highly regulated in their distribution and efficacy - a phenomenon which influences the individual cell's response to central signals of NM release. Even though NM receptor regulation is…

分子网络 · 定量生物学 2007-05-23 Gabriele Scheler

Achieving precise synchronisation between transmitters and receivers is particularly challenging in diffusive molecular communication environments. To this end, point-to-point molecular communication system design is examined wherein…

信号处理 · 电气工程与系统科学 2018-11-09 Tze-Yang Tung , Urbashi Mitra

Wideband communication is often expected to deal with a very wide spectrum, which in many environments of interest includes strong interferers. Thus receivers for the wideband communication systems often need to mitigate interferers to…

信息论 · 计算机科学 2020-06-04 Dian Mo , Marco F. Duarte

We explore the stationary densities and domain walls in the steady states of a pair of asymmetric exclusion processes (TASEP) antiparallelly coupled to two particle reservoirs without any spatial extent by using the model in Haldar et al.,…

统计力学 · 物理学 2026-02-13 Sourav Pal , Parna Roy , Abhik Basu

By numerical integration, we study the relaxation dynamics of degenerate harmonic oscillator modes dispersively coupled to particle positions. Depending on whether the effective inertial potential induced by the oscillators keep the…

介观与纳米尺度物理 · 物理学 2017-09-13 Christin Rhen , Andreas Isacsson

Synaptic dynamics, such as long- and short-term plasticity, play an important role in the complexity and biological realism achievable when running neural networks on a neuromorphic IC. For example, they endow the IC with an ability to…

Motivated by single-molecule experiments on synaptic membrane protein domains, we use a stochastic lattice model to study protein reaction and diffusion processes in crowded membranes. We find that the stochastic reaction-diffusion dynamics…

亚细胞过程 · 定量生物学 2016-11-08 Osman Kahraman , Yiwei Li , Christoph A. Haselwandter

In this study, we propose and analyze in simulations a new, highly flexible method of implementing synaptic plasticity in a wafer-scale, accelerated neuromorphic hardware system. The study focuses on globally modulated STDP, as a special…

神经元与认知 · 定量生物学 2013-08-21 Simon Friedmann , Nicolas Frémaux , Johannes Schemmel , Wulfram Gerstner , Karlheinz Meier

We study the synchronization of two model neurons coupled through a synapse having an activity-dependent strength. Our synapse follows the rules of Spike-Timing Dependent Plasticity (STDP). We show that this plasticity of the coupling…

Cell neighbor exchanges play a critical role in regulating tissue fluidity during epithelial morphogenesis and repair. In vivo, these neighbor exchanges are often hindered by the formation of transiently stable four-fold vertices, which can…

生物物理 · 物理学 2023-10-17 Fernanda Pérez-Verdugo , Shiladitya Banerjee