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In this research note, we present a set of distortion solutions that may be used to correct geometric optical distortion in images taken with the S13 camera of the NACO adaptive optics imager.
An optical imaging system forms an object image by recollecting light scattered by the object. However, intact optical information of the object delivered through the imaging system is deteriorated by imperfect optical elements and unwanted…
The utility of optical coherence tomography signal intensity for measurement of glucose concentration has been analysed in tissue phantom and blood samples from human subjects. The diffusion equation based calculations as well as in-vivo…
Coherent interferometric scattering microscopy (iscat) enables nanoparticle tracking on microsecond timescales and with nanometer precision, and has become a key tool in structural and cellular biophysics. The achievable localization…
Optical diffraction tomography (ODT) is a tomographic technique that can be used to measure the three-dimensional (3D) refractive index distribution within living cells without the requirement of any marker. In principle, ODT can be…
Background: Dual-energy (DE) imaging techniques in cone-beam computed tomography (CBCT) have potential clinical applications, including material quantification and improved tissue visualization. However, the performance of DE CBCT is…
Optical coherence tomography (OCT) has stimulated a wide range of medical image-based diagnosis and treatment in fields such as cardiology and ophthalmology. Such applications can be further facilitated by deep learning-based…
We present a general theory of optical coherence tomography (OCT), which synthesizes the fundamental concepts and implementations of OCT under a common 3D k-space framework. At the heart of this analysis is the Fourier diffraction theorem,…
Mass density is a vital property for improved biophysical understanding of and within biological samples. It is increasingly attracting active investigation, but still lacks reliable, non-contact techniques to accurately characterize it in…
Spatial resolution in optical microscopy has traditionally been treated as a fixed parameter of the optical system. Here, we present an approach to enhance transverse resolution in beam-scanned optical coherence tomography (OCT) beyond its…
Prevalent Computational Aberration Correction (CAC) methods are typically tailored to specific optical systems, leading to poor generalization and labor-intensive re-training for new lenses. Developing CAC paradigms capable of generalizing…
Optical coherence tomography (OCT) is a prevalent non-invasive imaging method which provides high resolution volumetric visualization of retina. However, its inherent defect, the speckle noise, can seriously deteriorate the tissue…
Optical Coherence Tomography (OCT) is one of the most important retinal imaging technique. However, involuntary motion artifacts still pose a major challenge in OCT imaging that compromises the quality of downstream analysis, such as…
Optical coherence tomography (OCT) is a non-invasive volumetric imaging modality with high spatial and temporal resolution. For imaging larger tissue structures, OCT probes need to be moved to scan the respective area. For handheld…
Optical coherence tomography offers astounding opportunities to image the complex structure of living tissue, but lacks functional information. We present dynamic full-field optical coherence tomography to image living human induced…
We develop a model of full-field optical coherence tomography (FF-OCT) that includes a description of partial temporal and spatial coherence, together with a mean-field scattering theory going beyond the Born approximation. Based on…
We use a spatial light modulator in a diffraction tomographic system to assess the accuracy of different refractive index reconstruction algorithms. Optical phase conjugation principles through complex media, allows us to quantify the error…
Intracoronary Optical Coherence Tomography (OCT) enables high-resolution visualization of coronary vessel anatomy but presents challenges due to noise, imaging artifacts, and complex tissue structures. This paper proposes a fully automated…
In tomographic reconstruction, the image quality of the reconstructed images can be significantly degraded by defects in the measured two-dimensional (2D) raw image data. Despite the importance of screening defective 2D images for robust…
We present Defocusing Microscopy (DM), a bright-field optical microscopy technique able to perform total 3D imaging of transparent objects. By total 3D imaging we mean the determination of the actual shapes of the upper and lower surfaces…