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The motility of a fish keratocyte on a flat substrate exhibits two distinct regimes: the non-migrating and the migrating one. In both configurations the shape is fixed in time and, when the cell is moving, the velocity is constant in…

细胞行为 · 定量生物学 2016-06-29 Davide Ambrosi , Anna Zanzottera

Swimming cells and microorganisms are as diverse in their collective dynamics as they are in their individual shapes and propulsion mechanisms. Even for sperm cells, which have a stereotyped shape consisting of a cell body connected to a…

流体动力学 · 物理学 2018-06-25 S. F. Schoeller , E. E. Keaveny

Sperm swimming is crucial to fertilise the egg, in nature and in assisted reproductive technologies. Modelling the sperm dynamics involves elasticity, hydrodynamics, internal active forces, and out-of-equilibrium noise. Here we demonstrate…

软凝聚态物质 · 物理学 2023-06-26 C. Maggi , B. Nath , F. Saglimbeni , V. Carmona Sosa , R. Di Leonardo , A. Puglisi

In single-molecule experiments, the dynamics of molecular motors are often observed indirectly by measuring the trajectory of an attached bead in a motor-bead assay. In this work, we propose a method to extract the step size and stalling…

统计力学 · 物理学 2023-05-05 Benjamin Ertel , Jann van der Meer , Udo Seifert

To rotate continuously without jamming, the flagellar filaments of bacteria need to be locked in phase. While several models have been proposed for eukaryotic flagella, the synchronization of bacterial flagella is less well understood.…

软凝聚态物质 · 物理学 2022-05-27 Maria Tătulea-Codrean , Eric Lauga

Molecular motors interacting with cytoskeletal filaments undergo peculiar random walks consisting of alternating sequences of directed movements along the filaments and diffusive motion in the surrounding solution. An ensemble of motors is…

统计力学 · 物理学 2007-05-23 Theo M. Nieuwenhuizen , Stefan Klumpp , Reinhard Lipowsky

Flagellated bacteria on nutrient-rich substrates can differentiate into a swarming state and move in dense swarms across surfaces. A recent experiment measured the flow in the fluid around an Escherichia coli swarm (Wu, Hosu and Berg, 2011…

生物物理 · 物理学 2016-07-28 Justas Dauparas , Eric Lauga

We study the chemotaxis of a population of genetically identical swimming bacteria undergoing run and tumble dynamics driven by stochastic switching between clockwise and counterclockwise rotation of the flagellar rotary system.…

细胞行为 · 定量生物学 2020-07-17 Margaritis Voliotis , Jerko Rosko , Teuta Pilizota , Tanniemola Liverpool

Bacteria predate plants and animals by billions of years. Today, they are the world's smallest cells yet they represent the bulk of the world's biomass, and the main reservoir of nutrients for higher organisms. Most bacteria can move on…

流体动力学 · 物理学 2016-01-20 Eric Lauga

Motor-driven cargo transport is a complex phenomenon where multiple motor proteins attached on to a cargo engage in pulling activity, often leading to tug-of-war, displaying bidirectional motion. However, most mathematical and computational…

生物物理 · 物理学 2016-09-09 Deepak Bhat , Manoj Gopalakrishnan

The statistical physics and dynamics of double supported bilayers are studied theoretically. The main goal in designing double supported lipid bilayers is to obtain model systems of biomembranes: the upper bilayer is meant to be almost…

软凝聚态物质 · 物理学 2015-03-13 Manoel Manghi , Nicolas Destainville

The motility mechanism of certain rod-shaped bacteria has long been a mystery, since no external appendages are involved in their motion which is known as gliding. However, the physical principles behind gliding motility still remain poorly…

生物物理 · 物理学 2020-03-25 Joël Tchoufag , Pushpita Ghosh , Connor B. Pogue , Beiyan Nan , Kranthi K. Mandadapu

Single flagellated bacteria are ubiquitous in nature. They exhibit various swimming modes using their flagella to explore complex surroundings such as soil and porous polymer networks. Some single-flagellated bacteria swim with two distinct…

软凝聚态物质 · 物理学 2024-11-20 H. Gidituri , M. Ellero , F. Balboa Usabiaga

In this paper we present a hydrodynamic approach to describe the motion of migrating bacteria as a special class of self-propelled systems. Analytical and numerical calculations has been performed to study the behavior of our model in the…

软凝聚态物质 · 物理学 2015-06-25 Zoltan Csahok , Andras Czirok

We study a Markov random process describing a muscle molecular motor behavior. Every motor is either bound up with a thin filament or unbound. In the bound state the motor creates a force proportional to its displacement from the neutral…

数学物理 · 物理学 2009-11-13 Yu. Kondratiev , E. Pechersky , S. Pirogov

Burgeoning interest in the area of bacteria-powered micro robotic systems prompted us to study the dynamics of cargo transport by single bacteria. In this paper, we have studied the swimming behaviour of oil-droplets attached as a cargo to…

软凝聚态物质 · 物理学 2020-05-26 P. Prakash , A. Z. Abdulla , V. Singh , M. Varma

We study the transport of bacteria in a porous media modeled by a square channel containing one cylindrical obstacle via molecular dynamics simulations coupled to a lattice Boltzmann fluid. Our bacteria model is a rod-shaped rigid body…

软凝聚态物质 · 物理学 2020-11-30 Miru Lee , Christoph Lohrmann , Kai Szuttor , Harold Auradou , Christian Holm

Kinesin motors can induce a buckling instability in a microtubule with a fixed minus end. Here we show that by modifying the surface with a protein-repellent functionalization and using clusters of kinesin motors, the microtubule can…

Bacteria such as Escherichia coli move about in a series of runs and tumbles: while a run state (straight motion) entails all the flagellar motors spinning in counterclockwise mode, a tumble is caused by a shift in the state of one or more…

定量方法 · 定量生物学 2020-01-08 C. S. Renadheer , Ushasi Roy , Manoj Gopalakrishnan

Many bacteria use rotating helical flagellar filaments to swim. The filaments undergo polymorphic transformations in which the helical pitch and radius change abruptly. These transformations arise in response to mechanical loading, changes…

软凝聚态物质 · 物理学 2010-05-26 Srikanth V. Srigiriraju , Thomas R. Powers