相关论文: Modeling Microscopic Chemical Sensors in Capillari…

A design for a pump is suggested which is based on well-known peristaltic pumps. In order to simply describe the operation of the proposed pump, an innovative interpretation of low Reynolds number swimmers is presented and thereafter a…

Recent experiments have demonstrated that highly charged ions can be guided through insulating nanocapillaries along the direction of the capillary axis for a surprisingly wide range of injection angles. Even more surprisingly, the…

Size and shape are critical discriminators between molecular species and states. We describe a micro-chip based high-throughput imaging approach offering rapid and precise determination of molecular properties under native solution…

Multi-component fluid flow simulations in multi-scale porous structures often involve regions that are under-resolved at practical computational resolutions. Accurately capturing the contributions from these unresolved regions is critical.…

We present direct experimental evidence that water droplets can spontaneously penetrate non-wetting capillaries, driven by the action of Laplace pressure due to high droplet curvature. Using high-speed optical imaging, microcapillaries of…

Solute transport is modeled using mixture theory, applied to the nanoparticle accumulation and concentration decay in the tissue space for different vascular configurations. A comparison of a single capillary configuration (SBC) with two…

In vascular targeted therapies, blood-borne carriers should realize sustained drug release from the luminal side towards the diseased tissue. In this context, such carriers are required to firmly adhere to the vessel walls for a sufficient…

Human blood flow is a multi-scale problem: in first approximation, blood is a dense suspension of plasma and deformable red cells. Physiological vessel diameters range from about one to thousands of cell radii. Current computational models…

Capillary filling in small length scale is an important process in nanotechnology and microfabrication. When one end of the tube or channel is sealed, it is important to consider the escape of the trapped gas. We develop a dynamic model on…

We simulate the electron transmission through insulating Mylar (PET) capillaries. We show that the mechanisms underlying the recently discovered electron guiding are fundamentally different from those for ion guiding. Quantum reflection and…

We propose a portable cartridge based lab-on-a-chip platform. The main sensing mechanism uses high frequency acoustic waves. Feasibility of two different transducers has been investigated for biological measurements. We used zincoxide (ZnO)…

The dynamic analysis of erythrocyte deformability is used as an important means for early diagnosis of blood diseases and blood rheology. Yet no effective method is available in terms of three-dimensional reconstruction of erythrocytes in a…

Accessing fluid infiltration in nanogranular coatings is an outstanding challenge, of relevance for applications ranging from nanomedicine to catalysis. A sensing platform, allowing to quantify the amount of fluid infiltrated in a…

In chemical processing and bioprocessing, conventional online sensors are limited to measure only basic process variables like pressure and temperature, pH, dissolved O and CO$_2$ and viable cell density (VCD). The concentration of other…

Microcapsules with liquid cores encapsulated by thin membranes have many applications in science, medicine and industry. In this paper, we design a suspension of microcapsules which flow and deform like red blood cells (RBCs), as a valuable…

Recent research has shown that motile cells can adapt their mode of propulsion depending on the environment in which they find themselves. One mode is swimming by blebbing or other shape changes, and in this paper we analyze a class of…

We investigate the dynamics of the Red Blood Cell (RBC) in microfluidic channels under oscillatory flows. The simulations employ a hybrid continuum-particle approach, in which the cell membrane and cytosol fluid are modeled using…

Modern theories of the hydrophobic effect highlight its dependence on length scale, emphasizing in particular the importance of interfaces that emerge in the vicinity of sizable hydrophobes. We recently showed that a faithful treatment of…

We present the state-of-the-art theoretical modeling, molecular simulation, and coarse-graining strategies for the transport of gases and liquids in nanoporous materials (pore size 1-100 nm). Special emphasis is placed on the transport of…

Computational modeling and simulation are presented on the motion of red blood cells behind a moving interface in a capillary. The methodology is based on an immersed boundary method and the skeleton structure of the red blood cell (RBC)…