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A key problem of eukaryotic cell motility is the signaling mechanism of chemoattractant gradient sensing. Recent experiments have revealed the molecular correlate of gradient sensing: Frontness molecules, such as PI3P and Rac, localize at…

细胞行为 · 定量生物学 2007-05-23 Atul Narang

Cell polarization is a critical process that separates molecular species into two distinct regions in prokaryotic and eukaryotic cells, guiding biological processes such as cell division and cell differentiation. Although several underlying…

分子网络 · 定量生物学 2025-01-28 Yixuan Chen , Guoye Guan , Lei-Han Tang , Chao Tang

Cell polarization underlies many cellular processes, such as differentiation, migration, and budding. Many living cells, such as budding yeast and fission yeast, use cytoskeletal structures to actively transport proteins to one location on…

生物物理 · 物理学 2022-06-22 Harmen Wierenga , Pieter Rein ten Wolde

The circular polarization of light that planets reflect is often neglected because it is very small compared to the linear polarization. It could, however, provide information on a planet's atmosphere and surface, and on the presence of…

地球与行星天体物理 · 物理学 2018-08-29 Loïc Rossi , Daphne M. Stam

The skin forms an efficient barrier against the environment, and rapid cutaneous wound healing after injury is therefore essential. Healing of the uppermost layer of the skin, the epidermis, involves collective migration of keratinocytes,…

细胞行为 · 定量生物学 2015-07-31 Matthias Jörg Fuhr , Michael Meyer , Eric Fehr , Gilles Ponzio , Sabine Werner , Hans Jürgen Herrmann

We study the phase diagram of director structures in cholesteric liquid crystals of negative dielectric anisotropy in homeotropic cells of thickness d which is smaller than the cholesteric pitch p. The basic control parameters are the…

We study a generic model for the polarisation and motility of self-propelled soft objects, biological cells or biomimetic systems, interacting with a viscous substrate. The active forces generated by the cell on the substrate are modelled…

软凝聚态物质 · 物理学 2015-06-23 M. Leoni , P. Sens

It has been long recognized that the spatial polarization of the electronic clouds in molecules, and the spatial arrangements of atoms into chiral molecular structures, play crucial roles in physics, chemistry and biology. However, these…

光学 · 物理学 2020-04-14 David Ayuso , Andres Ordonez , Piero Decleva , Misha Ivanov , Olga Smirnova

Here we characterized an information measure for cell polarity that applies to non-motile cells responding to a chemical gradient. The central idea is that polarization represents information about the direction of the gradient. We applied…

细胞行为 · 定量生物学 2025-04-14 Tau-Mu Yi

Cell polarity and movement are fundamental to many biological functions. Experimental and theoretically studies have indicated that interactions of certain proteins lead to the cell polarization which plays a key role in controlling the…

动力系统 · 数学 2022-08-12 Shuang Liu , Li-Tien Cheng , Bo Li

The electropermeabilization of biological cell membranes by the application of an external field occurs whenever an applied field exceeds a threshold value. For fields above this threshold value but less than another critical value, the…

生物物理 · 物理学 2007-05-23 William A. Hercules , James Lindesay , Anna Coble , Robert Schmukler

Since the lipid raft model was developed at the end of the last century, it became clear that the specific molecular arrangements of phospholipid assemblies within a membrane have profound implications in a vast range of physiological…

软凝聚态物质 · 物理学 2024-04-19 Alexander P. Fellows , Ben John , Martin Wolf , Martin Thämer

We propose a model for cell polarization as a response to an external signal which results in a system of PDEs for different variants of a protein on the cell surface and interior respectively. We study stationary states of this model in…

偏微分方程分析 · 数学 2019-02-18 Barbara Niethammer , Matthias Röger , Juan J. L. Velázquez

The combination of protrusions and retractions in the movement of polarized cells leads to understand the effect of possible synchronisation between the two ends of the cells. This synchronisation, in turn, could lead to different dynamics…

细胞行为 · 定量生物学 2021-09-21 Gissell Estrada-Rodriguez , Benoit Perthame

We develop a theory of polarized photoluminescence of interface excitons localized at lateral heterojunctions between transition metal dichalcogenide monolayers. We show that the circular selection rules governing interband optical…

介观与纳米尺度物理 · 物理学 2026-03-26 M. V. Durnev , D. S. Smirnov

Biological molecules are characterized by an intrinsic asymmetry known as homochirality. The result is optical activity of biological materials and circular polarization in the light scattered by microorganisms, cells of living organisms,…

地球与行星天体物理 · 物理学 2014-06-13 Lev Nagdimunov , Ludmilla Kolokolova , Daniel Mackowski

During cell migration, cells become polarized, change their shape, and move in response to various internal and external cues. Cell polarization is defined through the spatio-temporal organization of molecules such as PI3K or small GTPases,…

生物物理 · 物理学 2016-07-07 Fabian Spill , Vivi Andasari , Michael Mak , Roger D. Kamm , Muhammad H. Zaman

In metazoans, cells collectively polarize and align along the tissue plane. This phenomenon is called Planar cell polarity (PCP). Polarization means asymmetric segregation of molecules and sub-cellular structures within a cell. In PCP,…

适应与自组织系统 · 物理学 2023-08-22 Talagadadeevi Nirupamateja , Siva Sai Himakar Sreerangam , Biplab Bose

The clarification of the motion alignment mechanism in collective cell migration is an important issue commonly in physics and biology. In analogy with the self-propelled disk, the polarity memory effect of eukaryotic cell is a fundamental…

细胞行为 · 定量生物学 2019-10-02 Katsuyoshi Matsushita , Kazuya Horibe , Naoya Kamamoto , Koichi Fujimoto

The full time-dependent four-wave mixing polarization in quantum dots is microscopically calculated, taking into account acoustic phonon-assisted transitions between different exciton states of the dot. It is shown that quite different…

介观与纳米尺度物理 · 物理学 2007-05-23 E. A. Muljarov , R. Zimmermann