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Active particle tracking microrheometers have the potential to perform accurate broad-band measurements of viscoelasticity within microscopic systems. Generally, their largest possible precision is limited by Brownian motion and low…

Molecular combing is a powerful and simple method for aligning DNA molecules onto a surface. Using this technique combined with fluorescence microscopy, we observed that the length of lambda-DNA molecules was extended to about 1.6 times…

生物大分子 · 定量生物学 2009-11-10 Yu-Ying Liu , Peng-Ye Wang , Shuo-Xing Dou , Wei-Chi Wang , Ping Xie , Hua-Wei Yin , Xing-Dong Zhang

Continuum models are commonly used to study dendritic deposition in fields ranging from nonequilibrium statistical mechanics to battery research. However, the continuum approximation underlying these models is poorly understood, even in the…

统计力学 · 物理学 2025-04-09 Daniel Jacobson , Thomas F. Miller

Wave packet molecular dynamics (WPMD) has recently received a lot of attention as a computationally fast tool to study dynamical processes in warm dense matter beyond the Born-Oppenheimer approximation. These techniques, typically, employ…

等离子体物理 · 物理学 2021-04-09 William A. Angermeier , Thomas G. White

Using Brownian dynamics simulations, we study the migration of long charged chains in an electrophoretic microchannel device consisting of an array of microscopic entropic traps with alternating deep regions and narrow constrictions. Such a…

生物物理 · 物理学 2007-05-23 Martin Streek , Friederike Schmid , Thanh Tu Duong , Alexandra Ros

An elastic rod model for semi-flexible polymers is presented. Theory for a continuum rod is reviewed, and it is shown that a popular discretised model used in numerical simulations gives the correct continuum limit. Correlation functions…

生物物理 · 物理学 2014-04-08 C. A. Brackley , A. N. Morozov , D. Marenduzzo

Brownian motion is essential for describing diffusion in systems ranging from simple to complex liquids. Unlike simple liquids, which consist of only a solvent, complex liquids, such as colloidal suspensions or the cytoplasm of a cell, are…

软凝聚态物质 · 物理学 2025-02-27 Jeffrey C. Everts , Robert Hołyst , Karol Makuch

DNA-functionalized particles have great potential for the design of complex self-assembled materials. The major hurdle in realizing crystal structures from DNA-functionalized particles is expected to be kinetic barriers that trap the system…

软凝聚态物质 · 物理学 2015-03-06 Yajun Ding , Jeetain Mittal

The dynamics of an optically trapped particle are often determined by measuring intensity shifts of the back-scattered light from the particle using position sensitive detectors. We present a technique which measures the phase of the…

In this paper, we propose a deep learning-based beam tracking method for millimeter-wave (mmWave)communications. Beam tracking is employed for transmitting the known symbols using the sounding beams and tracking time-varying channels to…

信号处理 · 电气工程与系统科学 2022-12-05 Sun Hong Lim , Sunwoo Kim , Byonghyo Shim , Jun Won Choi

The particle-scale dynamics of granular materials have commonly been characterized by the self-diffusion coefficient $D$. However, this measure discards the collective and topological information known to be an important characteristic of…

软凝聚态物质 · 物理学 2013-05-28 James G. Puckett , Frédéric Lechenault , Karen E. Daniels , Jean-Luc Thiffeault

By extending the classical Peyrard-Bishop model, we are able to obtain a fully analytical description for the mechanical resistance of DNA under stretching at variable values of temperature, number of base pairs and intrachains and…

软凝聚态物质 · 物理学 2022-07-20 G. Florio , G. Puglisi

Direct detector device (DDD) cameras have revolutionized single particle electron cryomicroscopy (cryo-EM). In addition to an improved camera detective quantum efficiency, acquisition of DDD movies allows for correction of movement of the…

定量方法 · 定量生物学 2015-11-23 John L. Rubinstein , Marcus A. Brubaker

Recent electronic transport experiments using metallic contacts attached to proteins identified some 'stylized facts' which contradict conventional wisdom that increasing either the spatial distance between the electrodes or the temperature…

无序系统与神经网络 · 物理学 2019-09-04 Eszter Papp , Dávid P. Jelenfi , Máté T. Veszeli , Gábor Vattay

We present a self-contained theory for the mechanical response of DNA in single molecule experiments. Our model is based on a 1D continuum description of the DNA molecule and accounts both for its elasticity and for DNA-DNA electrostatic…

生物大分子 · 定量生物学 2015-05-13 N. Clauvelin , B. Audoly , S. Neukirch

Calculation of Raman scattering from molecular dynamics (MD) simulations requires accurate modeling of the evolution of the electronic polarizability of the system along its MD trajectory. For large systems, this necessitates the use of…

Modern genomics experiments measure functional behaviors for many thousands of DNA sequences. We suggest that, especially when these sequences are chosen at random, it is natural to compute correlation functions between sequences and…

生物物理 · 物理学 2020-12-14 Yaojun Zhang , Aakash Basu , Taekjip Ha , William Bialek

The fidelity of DNA replication by DNA polymerase (DNAP) has long been an important issue in biology. While numerous experiments have revealed details of the molecular structure and working mechanism of DNAP which consists of both a…

亚细胞过程 · 定量生物学 2016-11-29 Yong-Shun Song , Yao-Gen Shu , Xin Zhou , Zhong-Can Ou-Yang , Ming Li

In diverse biological applications, particle tracking of passive microscopic species has become the experimental measurement of choice -- when either the materials are of limited volume, or so soft as to deform uncontrollably when…

应用统计 · 统计学 2019-11-18 Yun Ling , Martin Lysy , Ian Seim , Jay M. Newby , David B. Hill , Jeremy Cribb , M. Gregory Forest

The thermal conductivity of nanometric objects or nanostructured materials can be determined using non equilibrium molecular dynamics (NEMD) simulations. The technique is simple in its principle, and resembles a numerical guarded hot plate…

材料科学 · 物理学 2007-05-23 Patrice Chantrenne , Jean-Louis Barrat