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The primary aim of this paper is to comprehend, assess, and analyze the role, relevance, and efficiency of machine learning models in predicting heart disease risks using clinical data. While the importance of heart disease risk prediction…

Ancestral maximum likelihood (AML) is a method that simultaneously reconstructs a phylogenetic tree and ancestral sequences from extant data (sequences at the leaves). The tree and ancestral sequences maximize the probability of observing…

种群与进化 · 定量生物学 2017-07-24 Elchanan Mossel , Sebastien Roch , Mike Steel

Kidney transplantation is the preferred treatment for people suffering from end-stage renal disease. Successful kidney transplants still fail over time, known as graft failure; however, the time to graft failure, or graft survival time, can…

机器学习 · 计算机科学 2022-11-07 Zhipeng Huang , Kevin S. Xu

Cardiovascular diseases and their associated disorder of heart failure are one of the major death causes globally, being a priority for doctors to detect and predict its onset and medical consequences. Artificial Intelligence (AI) allows…

机器学习 · 计算机科学 2023-10-31 Pedro A. Moreno-Sanchez

People with learning disabilities have a higher mortality rate and premature deaths compared to the general public, as reported in published research in the UK and other countries. This study analyses hospitalisations of 9,618 patients…

Latent tree analysis seeks to model the correlations among a set of random variables using a tree of latent variables. It was proposed as an improvement to latent class analysis --- a method widely used in social sciences and medicine to…

机器学习 · 计算机科学 2016-10-04 Nevin L. Zhang , Leonard K. M. Poon

Interpretability is crucial for doctors, hospitals, pharmaceutical companies and biotechnology corporations to analyze and make decisions for high stakes problems that involve human health. Tree-based methods have been widely adopted for…

机器学习 · 计算机科学 2024-05-24 Rui Zhang , Rui Xin , Margo Seltzer , Cynthia Rudin

Numerous tutorials and research papers focus on methods in either survival analysis or causal inference, leaving common complications in medical studies unaddressed. In practice one must handle problems jointly, without the luxury of…

应用统计 · 统计学 2020-11-25 Camila Olarte Parra , Ingeborg Waernbaum , Staffan Schön , Els Goetghebeur

We introduce a new survival tree method for censored failure time data that incorporates three key advancements over traditional approaches. First, we develop a more computationally efficient splitting procedure that effectively mitigates…

统计方法学 · 统计学 2025-09-24 Ruiwen Zhou , Ke Xie , Lei Liu , Zhichen Xu , Jimin Ding , Xiaogang Su

Patient life circumstances, including social determinants of health (SDOH), shape both health outcomes and care access, contributing to persistent disparities across gender, race, and socioeconomic status. Liver transplantation exemplifies…

Hospital readmission has become a critical metric of quality and cost of healthcare. Medicare anticipates that nearly $17 billion is paid out on the 20% of patients who are readmitted within 30 days of discharge. Although several…

应用统计 · 统计学 2014-03-14 Issac Shams , Saeede Ajorlou , Kai Yang

Utilizing clinical texts in survival analysis is difficult because they are largely unstructured. Current automatic extraction models fail to capture textual information comprehensively since their labels are limited in scope. Furthermore,…

计算与语言 · 计算机科学 2021-05-04 Hyun Gi Lee , Evan Sholle , Ashley Beecy , Subhi Al'Aref , Yifan Peng

The Yule (pure-birth) model is the simplest null model of speciation; each lineage gives rise to a new lineage independently with the same rate $\lambda$. We investigate the expected length of an edge chosen at random from the resulting…

种群与进化 · 定量生物学 2009-10-29 Mike Steel , Arne Mooers

Diverse analysis approaches have been proposed to distinguish data missing due to death from nonresponse, and to summarize trajectories of longitudinal data truncated by death. We demonstrate how these analysis approaches arise from…

统计方法学 · 统计学 2010-01-18 Brenda F. Kurland , Laura L. Johnson , Brian L. Egleston , Paula H. Diehr

Interval-censored data, in which the event time is only known to lie in some time interval, arise commonly in practice; for example, in a medical study in which patients visit clinics or hospitals at pre-scheduled times, and the events of…

统计方法学 · 统计学 2017-07-21 Wei Fu , Jeffrey S. Simonoff

Despite the fact that cancer survivability rates vary greatly between stages, traditional survival prediction models have frequently been trained and assessed using examples from all combined phases of the disease. This method may result in…

机器学习 · 计算机科学 2026-01-08 Parisa Poorhasani , Bogdan Iancu

A linear mixed-effects (LME) model is proposed for modelling and forecasting single and multi-population age-specific death rates (ASDRs). The innovative approach that we take in this study treats age, the interaction between gender and…

应用统计 · 统计学 2025-11-18 Reza Dastranj , Martin Kolar

Estimating individualized treatment rules is a central task for personalized medicine. [zhao2012estimating] and [zhang2012robust] proposed outcome weighted learning to estimate individualized treatment rules directly through maximizing the…

统计方法学 · 统计学 2017-10-02 Yifan Cui , Ruoqing Zhu , Michael Kosorok

Amyotrophic lateral sclerosis (ALS) is a severe disease with a typical survival of 3-5 years after symptom onset. Current treatments offer only limited life extension, and the variability in patient responses highlights the need for…

机器学习 · 计算机科学 2025-11-05 Guillaume Tejedor , Veronika Peralta , Nicolas Labroche , Patrick Marcel , Hélène Blasco , Hugo Alarcan

Heart failure is a life-threatening condition that affects millions of people worldwide. The ability to accurately predict patient survival can aid in early intervention and improve patient outcomes. In this study, we explore the potential…

机器学习 · 计算机科学 2023-08-14 Md. Simul Hasan Talukder , Rejwan Bin Sulaiman , Mouli Bardhan Paul Angon