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The human brain is ultimately responsible for all thoughts and movements that the body produces. This allows humans to successfully interact with their environment. If the brain is not functioning properly many abilities of human can be…

神经元与认知 · 定量生物学 2018-07-09 Esmaeil Seraj

Understanding how neural dynamics shape cognitive experiences remains a central challenge in neuroscience and psychiatry. Here, we present a novel framework leveraging state-to-output controllability from dynamical systems theory to model…

The brain is in a state of perpetual reverberant neural activity, even in the absence of specific tasks or stimuli. Shedding light on the origin and functional significance of such a dynamical state is essential to understanding how the…

统计力学 · 物理学 2022-07-08 Guillermo B. Morales , Serena Di Santo , Miguel A. Munoz

Brain connectomics is still largely dominated by pairwise-based models, such as graphs, which cannot represent circulatory or higher-order functional interactions. In this paper, we propose a multimodal framework based on Topological Signal…

神经元与认知 · 定量生物学 2026-04-01 Breno C. Bispo , Stefania Sardellitti , Juliano B. Lima , Fernando A. N. Santos

Scaling temporal dynamics in functional MRI (fMRI) signals have been evidenced for a decade as intrinsic characteristics of ongoing brain activity (Zarahn et al., 1997). Recently, scaling properties were shown to fluctuate across brain…

统计理论 · 数学 2013-08-21 P. Ciuciu , G. Varoquaux , P. Abry , S. Sadaghiani , A. Kleinschmidt

Neural oscillations are considered to be brain-specific signatures of information processing and communication in the brain. They also reflect pathological brain activity in neurological disorders, thus offering a basis for diagnoses and…

神经元与认知 · 定量生物学 2023-10-23 Tena Dubcek , Debora Ledergerber , Jana Thomann , Giovanna Aiello , Marc Serra-Garcia , Lukas Imbach , Rafael Polania

Consciousness spans macroscopic experience and microscopic neuronal activity, yet linking these scales remains challenging. Prevailing theories, such as Integrated Information Theory, focus on a single scale, overlooking how causal power…

神经元与认知 · 定量生物学 2025-09-16 Zhipeng Wang , Yingqi Rong , Kaiwei Liu , Mingzhe Yang , Jiang Zhang , Jing He

The current paper proposes a novel neural network model for recognizing visually perceived human actions. The proposed multiple spatio-temporal scales recurrent neural network (MSTRNN) model is derived by introducing multiple timescale…

计算机视觉与模式识别 · 计算机科学 2017-02-23 Haanvid Lee , Minju Jung , Jun Tani

Brain function is organized in coordinated modes of spatio-temporal activity (functional networks) exhibiting an intrinsic baseline structure with variations under different experimental conditions. Existing approaches for uncovering such…

统计方法学 · 统计学 2019-02-13 Joshua Lukemire , Suprateek Kundu , Giuseppe Pagnoni , Ying Guo

Quantitative modeling of human brain activity based on language representations has been actively studied in systems neuroscience. However, previous studies examined word-level representation, and little is known about whether we could…

计算机视觉与模式识别 · 计算机科学 2018-02-08 Eri Matsuo , Ichiro Kobayashi , Shinji Nishimoto , Satoshi Nishida , Hideki Asoh

The continuous integration of experimental data into coherent models of the brain is an increasing challenge of modern neuroscience. Such models provide a bridge between structure and activity, and identify the mechanisms giving rise to…

神经元与认知 · 定量生物学 2017-03-03 Jannis Schuecker , Maximilian Schmidt , Sacha J. van Albada , Markus Diesmann , Moritz Helias

Background/Introduction: In this paper, the neural network class of Self-Organising Maps (SOMs) is investigated in terms of its theoretical and applied validity for cognitive modelling, particularly of neurodevelopmental disorders. Methods:…

神经元与认知 · 定量生物学 2025-07-18 Spyridon Revithis , Nadine Marcus

A fundamental idea in neuroscience is that cognitive functions -- such as perception, learning, memory, and locomotion -- are shaped and constrained by the brain's structural organization. Despite significant progress in mapping and…

神经元与认知 · 定量生物学 2025-08-07 Elkaïoum M. Moutuou , Habib Benali

Understanding the functional architecture of the brain in terms of networks is becoming increasingly common. In most fMRI applications functional networks are assumed to be stationary, resulting in a single network estimated for the entire…

We describe a chain of unidirectionally coupled adaptive excitable elements slowly driven by a stochastic process from one end and open at the other end, as a minimal toy model of unresolved irreducible uncertainty in a system performing…

神经元与认知 · 定量生物学 2022-09-14 Mario Martinez-Saito

Functional Magnetic Resonance Imaging (fMRI) is a primary modality for studying brain activity. Modeling spatial dependence of imaging data at different scales is one of the main challenges of contemporary neuroimaging, and it could allow…

应用统计 · 统计学 2016-06-16 Stefano Castruccio , Hernando Ombao , Marc G. Genton

Scaling data and artificial neural networks has transformed AI, driving breakthroughs in language and vision. Whether similar principles apply to modeling brain activity remains unclear. Here we leveraged a dataset of 3.1 million neurons…

Brain function emerges from coordinated activity across anatomically connected regions, where structural connectivity (SC) -- the network of white matter pathways - provides the physical substrate for functional connectivity (FC) -- the…

神经元与认知 · 定量生物学 2025-07-09 Sam Frank Kelemen , Joaquín Gõni , Sérgio Pequito , Arian Ashourvan

Coordinated human movement depends on the integration of multisensory inputs, sensorimotor transformation, and motor execution, as well as sensory feedback resulting from body-environment interaction. Building dynamic models of the…

神经元与认知 · 定量生物学 2025-06-03 Chenhui Zuo , Guohao Lin , Chen Zhang , Shanning Zhuang , Yanan Sui

We model sensory streams as observations from high-dimensional stochastic dynamical systems and conceptualize sensory neurons as self-supervised learners of compact representations of such dynamics. From prior experience, neurons learn…