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Halting a computer or biological virus outbreak requires a detailed understanding of the timing of the interactions between susceptible and infected individuals. While current spreading models assume that users interact uniformly in time,…

数据分析、统计与概率 · 物理学 2015-06-26 Alexei Vazquez , Racz Balazs , Lukacs Andras , Albert-Laszlo Barabasi

We study time continuous branching processes with exponentially distributed lifetimes, with two types of cells that proliferate according to binary fission. A range of possible system dynamics are considered, each of which is characterized…

概率论 · 数学 2022-04-27 Nam H Nguyen , Marek Kimmel

We consider mathematical models of infection diseases built by G.I. Marchuk in his well known book on immunology. These models are in the form of systems of ordinary delay differential equations. We add a distributed control in one of the…

细胞行为 · 定量生物学 2020-08-28 Irina Volinsky , Alexander Domoshnitsky , Marina Bershadsky , Roman Shklyar

We study epidemic models where the infectivity of each individual is a random function of the infection age (the elapsed time of infection). To describe the epidemic evolution dynamics, we use a stochastic process that tracks the number of…

概率论 · 数学 2023-01-02 Guodong Pang , Etienne Pardoux

Many pathogens spread primarily via direct contact between infected and susceptible hosts. Thus, the patterns of contacts or contact network of a population fundamentally shapes the course of epidemics. While there is a robust and growing…

种群与进化 · 定量生物学 2012-08-01 Shweta Bansal , Lauren Ancel Meyers

We propose a model of the immunity to a cyclical epidemic disease taking account not only of seasonal boosts during the infectious season, but also of residual immunity remaining from one season to the next. The focus is on the exponential…

种群与进化 · 定量生物学 2024-04-22 Siyu Chen , David Sankoff

In contrast to the common assumption in epidemic models that the rate of infection between individuals is constant, in reality, an individual's viral load determines their infectiousness. We compare the average and individual reproductive…

种群与进化 · 定量生物学 2021-12-07 Nicholas Landry

Models of disease spreading are critical for predicting infection growth in a population and evaluating public health policies. However, standard models typically represent the dynamics of disease transmission between individuals using…

物理与社会 · 物理学 2022-06-07 Christopher A. Browne , Daniel B. Amchin , Joanna Schneider , Sujit S. Datta

We formulate a model for the dynamics of respiratory droplets and use it to study their airborne lifetime in turbulent air representative of indoor settings. This lifetime is a common metric to assess the risk of respiratory transmission of…

医学物理 · 物理学 2022-06-15 Avshalom Offner , Jacques Vanneste

This article examines how diseases on random networks spread in time. The disease is described by a probability distribution function for the number of infected and recovered individuals, and the probability distribution is described by a…

适应与自组织系统 · 物理学 2013-05-29 M. Marder

We have derived the governing equations for an SIR model with delay terms in both the infectivity and recovery of the disease. The equations are derived by modelling the dynamics as a continuous time random walk, where individuals move…

As offered by the World Health Organisation (WHO), close to half of the population in the world's resides in dengue-risk zones. Dengue viruses are transmitted to individuals by Aedes mosquito species infected bite (Ae. Albopictus of Ae.…

种群与进化 · 定量生物学 2025-03-12 Burcu Gürbüz , Aytül Gökçe , Segun I. Oke , Michael O. Adeniyi , Mayowa M. Ojo

The spread of viruses in biological networks, computer networks, and human contact networks can have devastating effects; developing and analyzing mathematical models of these systems can be insightful and lead to societal benefits. Prior…

最优化与控制 · 数学 2016-09-19 Philip E. Paré , Angelia Nedić , Carolyn L. Beck

The incubation period of a disease is the time between an initiating pathologic event and the onset of symptoms. For typhoid fever, polio, measles, leukemia and many other diseases, the incubation period is highly variable. Some affected…

种群与进化 · 定量生物学 2017-06-01 Bertrand Ottino-Loffler , Jacob G. Scott , Steven H. Strogatz

Mathematical models of infectious disease transmission typically neglect within-host dynamics. Yet within-host dynamics - including pathogen replication, host immune responses, and interactions with microbiota - are crucial not only for…

种群与进化 · 定量生物学 2023-12-20 Cameron A. Smith , Ben Ashby

Infections diseases are marked by recovering time distributions which can be far from the exponential one associated with Markovian/Poisson processes, broadly applied in epidemic compartmental models. In the present work, we tackled this…

物理与社会 · 物理学 2024-10-03 José Carlos M. Silva , Diogo H. Silva , Francisco A. Rodrigues , Silvio C. Ferreira

The temporal dynamics of social interactions were shown to influence the spread of disease. Here, we model the conditions of progression and competition for several viral strains, exploring various levels of cross-immunity over temporal…

物理与社会 · 物理学 2022-06-14 Alex Abbey , Yuval Shahar , Osnat Mokryn

Mathematical modeling of biological systems is crucial to effectively and efficiently developing treatments for medical conditions that plague humanity. Often, systems of ordinary differential equations are a traditional tool used to…

经典分析与常微分方程 · 数学 2015-09-01 Eric Jones , Peter Roemer , Mrinal Raghupathi , Stephen Pankavich

The decentralized patch distribution mechanism holds significant promise as an alternative to its centralized counterpart. For the purpose of accurately evaluating the performance of the decentralized patch distribution mechanism and based…

社会与信息网络 · 计算机科学 2023-02-27 Lu-Xing Yang , Xiaofan Yang , Qingyi Zhu , Chenquan Gan

We introduce a general class of branching Markov processes for the modelling of a parasite infection in a cell population. Each cell contains a quantity of parasites which evolves as a diffusion with positive jumps. The drift, diffusive…

概率论 · 数学 2023-08-31 Aline Marguet , Charline Smadi