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Recent methods have been developed to map single-cell lineage statistics to population growth. Because population growth selects for exponentially rare phenotypes, these methods inherently depend on sampling large deviations from finite…

统计力学 · 物理学 2025-01-16 Trevor GrandPre , Ethan Levien , Ariel Amir

When linear regression generates a relationship between a (dependent) scalar response and one or multiple independent variables, various datasets providing distinct graphical trends can develop resembling relationships based on the same…

统计方法学 · 统计学 2021-08-27 Albert S. Kim

The recent explosion of genomic data has underscored the need for interpretable and comprehensive analyses that can capture complex phylogenetic relationships within and across species. Recombination, reassortment and horizontal gene…

定量方法 · 定量生物学 2016-09-28 Pablo G. Camara , Arnold J. Levine , Raul Rabadan

A combined experimental and theoretical study is carried out on the three-body recombination process in a gas of microwave-shielded polar molecules. For ground-state polar molecules dressed with a strong microwave field, field-linked bound…

The delay time distribution of neutron star mergers provides critical insights into binary evolution processes and the merger rate evolution of compact object binaries. However, current observational constraints on this delay time…

高能天体物理现象 · 物理学 2022-11-28 Michael Zevin , Anya E. Nugent , Susmita Adhikari , Wen-fai Fong , Daniel E. Holz , Luke Zoltan Kelley

In this thesis we focus on studying the physics of cosmological recombination and how the details of recombination affect the Cosmic Microwave Background (CMB) anisotropies. We present a detailed calculation of the spectral line distortions…

天体物理学 · 物理学 2008-11-19 Wan Yan Wong

We present results from an experiment similar to one performed by Packard (1988), in which a genetic algorithm is used to evolve cellular automata (CA) to perform a particular computational task. Packard examined the frequency of evolved CA…

adap-org · 物理学 2008-02-03 Melanie Mitchell , Peter Hraber , James P. Crutchfield

The constraints on the time variation of the fine structure constant at recombination epoch relative to its present value, $\Delta\alpha/\alpha \equiv (\alpha_{\mathrm{rec}} - \alpha_{\mathrm{now}})/\alpha_{\mathrm{now}}$, are obtained from…

天体物理学 · 物理学 2014-11-18 Masahiro Nakashima , Ryo Nagata , Jun'ichi Yokoyama

We develop and apply a new framework for reconstructing the ionization history during the epoch of recombination with combinations of cosmic microwave background (CMB), baryon acoustic oscillation (BAO) and supernova data. We find a wide…

宇宙学与河外天体物理 · 物理学 2024-08-15 Gabriel P. Lynch , Lloyd Knox , Jens Chluba

Motivated by a recently proposed design for a DNA coded randomised algorithm that enables inference of the average generation of a collection of cells descendent from a common progenitor, here we establish strong convergence properties for…

概率论 · 数学 2019-08-12 Gianfelice Meli , Tom S. Weber , Ken R. Duffy

Heterogeneous systems of active matter exhibit a range of complex emergent dynamical patterns. In particular, it is difficult to predict the properties of the mixed system based on its constituents. These considerations are particularly…

软凝聚态物质 · 物理学 2021-04-07 Shlomit Peled , Shawn D. Ryan , Sebastian Heidenreich , Markus Bar , Gil Ariel , Avraham Be'er

The WMAP team has recently highlighted the usefulness of combining the Ly-alpha forest constraints with those from the cosmic microwave background (CMB). This combination is particularly powerful as a probe of the primordial shape of the…

天体物理学 · 物理学 2009-11-07 Uros Seljak , Patrick McDonald , Alexey Makarov

The genome-wide recombination rate ($RR$) of a species is often described by one parameter, the ratio between total genetic map length ($G$) and physical map length ($P$), measured in centiMorgans per Megabase (cM/Mb). The value of this…

基因组学 · 定量生物学 2011-03-16 Wentian Li , Jan Freudenberg

The primordial curvature fluctuation spectrum is reconstructed by the cosmic inversion method using the five-year WMAP data of the cosmic microwave background temperature anisotropy. We apply the covariance matrix analysis and decompose the…

天体物理学 · 物理学 2008-12-30 Ryo Nagata , Jun'ichi Yokoyama

We investigate a family of $(\mu+\lambda)$ Genetic Algorithms (GAs) which creates offspring either from mutation or by recombining two randomly chosen parents. By scaling the crossover probability, we can thus interpolate from a fully…

神经与进化计算 · 计算机科学 2021-02-16 Furong Ye , Hao Wang , Carola Doerr , Thomas Bäck

An approximation to the ~4 Mbp basic genome shared by 32 strains of E. coli representing six evolutionary groups has been derived and analyzed computationally. A multiple-alignment of the 32 complete genome sequences was filtered to remove…

基因组学 · 定量生物学 2016-02-17 Purushottam Dixit , Tin Yau Pang , F. William Studier , Sergei Maslov

[Abridged] We use our most recent training set for the RICO code to estimate the impact of recombination uncertainties on the posterior probability distributions which will be obtained from future CMB experiments, and in particular the…

宇宙学与河外天体物理 · 物理学 2015-05-14 J. A. Rubino-Martin , J. Chluba , W. A. Fendt , B. D. Wandelt

An exponentially decaying system looks as if its decay was a generalized power or double-exponential law, provided one takes into account the relativistic time dilation in a detector, the delay of the emitted signal, and the accelerations…

经典物理 · 物理学 2025-01-22 Marek Czachor

We present up-to-date constraints on the value of the fine-structure constant at the epoch of decoupling from the recent observations made by the Wilkinson Microwave Anisotropy Probe (WMAP) satellite. In the framework of models we…

天体物理学 · 物理学 2008-11-26 C. J. A. P. Martins , A. Melchiorri , G. Rocha , R. Trotta , P. P. Avelino , P. Viana

Precise measurements of the anisotropies in the cosmic microwave background enable us to do an accurate study on the form of the primordial power spectrum for a given set of cosmological parameters. In a previous paper (Shafieloo and…