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Fluid-structure interactions between active and passive components are important for many biological systems to function. A particular example is chromatin in the cell nucleus, where ATP-powered processes drive coherent motions of the…

软凝聚态物质 · 物理学 2024-02-15 Scott Weady , David B. Stein , Alexandra Zidovska , Michael J. Shelley

Synaptic connections in neuronal circuits are modulated by pre- and post-synaptic spiking activity. Heuristic models of this process of synaptic plasticity can provide excellent fits to results from in-vitro experiments in which pre- and…

神经元与认知 · 定量生物学 2022-07-14 Federico Devalle , Alex Roxin

Neural field theory is used to quantitatively analyze the two-dimensional spatiotemporal correlation properties of gamma-band (30 -- 70 Hz) oscillations evoked by stimuli arriving at the primary visual cortex (V1), and modulated by patchy…

神经元与认知 · 定量生物学 2021-03-19 X. Liu , P. Sanz-Leon , P. A. Robinson

We model the elasticity of the cerebral cortex as a layered material with bending energy along the layers and elastic energy between them in both planar and polar geometries. The cortex is also subjected to axons pulling from the underlying…

软凝聚态物质 · 物理学 2016-02-09 O. V. Manyuhina , David Mayett , J. M. Schwarz

Understanding the cortical organization of the human brain requires interpretable descriptors for distinct structural and functional imaging data. 3D polarized light imaging (3D-PLI) is an imaging modality for visualizing fiber architecture…

The universal scaling law of cortical morphology describes cortical folding as the covariance of average grey matter thickness, pial surface area, and exposed surface area. It applies for mammalian species, humans, and across lobes, however…

神经元与认知 · 定量生物学 2021-03-29 Karoline Leiberg , Christoforos Papasavvas , Yujiang Wang

Human skill learning requires fine-scale coordination of distributed networks of brain regions that are directly linked to one another by white matter tracts to allow for effective information transmission. Yet how individual differences in…

神经元与认知 · 定量生物学 2016-10-25 Ari E. Kahn , Marcelo G. Mattar , Jean M. Vettel , Nicholas F. Wymbs , Scott T. Grafton , Danielle S. Bassett

Many processes in eukaryotic cells, including cell motility, rely on the growth of branched actin networks from surfaces. Despite its central role the mechano-chemical coupling mechanisms which guide the growth process are poorly…

软凝聚态物质 · 物理学 2015-06-23 Karin John , Denis Caillerie , Chaouqi Misbah

We study phase segregation in a model alloy undergoing both ordering and decomposition, using computer simulations of Kawasaki exchange dynamics on a square lattice. Following a quench into the miscibility gap we observe an early stage in…

统计力学 · 物理学 2009-10-30 V. Gorentsveig , P. Fratzl , J. L. Lebowitz

Communication within or between complex systems is commonplace in the natural sciences and fields such as graph neural networks. The brain is a perfect example of such a complex system, where communication between brain regions is…

神经元与认知 · 定量生物学 2022-10-10 Eloy Geenjaar , Noah Lewis , Amrit Kashyap , Robyn Miller , Vince Calhoun

In functionally complex systems, higher-order connectivity is often revealed in the underlying geometry of networked units. Furthermore, such systems often show signatures of self-organized criticality, a specific type of non-equilibrium…

统计力学 · 物理学 2026-03-11 Bosiljka Tadic , Roderick Melnik

Recent high precision experimental results on spin-glass films ask for a detailed understanding of the domain-growth dynamics of two-dimensional spin glasses. To achieve this goal, we numerically simulate the out-equilibrium dynamics of the…

无序系统与神经网络 · 物理学 2019-05-07 L. A. Fernandez , E. Marinari , V. Martin-Mayor , G. Parisi , J. J. Ruiz-Lorenzo

The steady sliding state of periodic structures such as charge density waves and flux line lattices is numerically studied based on two and three dimensional driven random field XY models. We focus on the dynamical phase transition between…

无序系统与神经网络 · 物理学 2009-11-11 Tomoaki Nogawa , Hajime Yoshino , Hiroshi Matsukawa

After a brief review of the historical role of analyticity in the study of critical phenomena, an account is given of recent discoveries of discretely holomorphic observables in critical two-dimensional lattice models. These are objects…

统计力学 · 物理学 2015-05-13 John Cardy

The ability of cells to sense and respond to the mechanical properties of their environments is fundamental to a range of cellular behaviours, with substrate stiffness increasingly being found to be a key signalling factor. Although active…

细胞行为 · 定量生物学 2019-09-04 Carina M. Dunlop

The visual system evolved to process natural scenes, yet most of our understanding of the topology and function of visual cortex derives from studies using artificial stimuli. To gain deeper insights into visual processing of natural…

神经元与认知 · 定量生物学 2023-07-25 Tianye Wang , Haoxuan Yao , Tai Sing Lee , Jiayi Hong , Yang Li , Hongfei Jiang , Ian Max Andolina , Shiming Tang

The field of visual and physiological optics is undergoing continuous significant advancements, driven by a deeper understanding of the human visual system and the development of cutting-edge optical technologies. This Roadmap, authored by…

The cerebral cortex is composed of multiple cortical areas that exert a wide variety of brain functions. Although human brain neurons are genetically and areally mosaic, the three-dimensional structural differences between neurons in…

In order to keep trace of information and grow up, the infant brain has to resolve the problem about where old information is located and how to index new ones. We propose that the immature prefrontal cortex (PFC) use its primary…

神经与进化计算 · 计算机科学 2022-01-03 Alexandre Pitti , Mathias Quoy , Catherine Lavandier , Sofiane Boucenna , Wassim Swaileh , Claudio Weidmann

This article proposes a research and development direction that would lead to the creation of next-generation intelligent technical systems. A distinctive feature of these systems is their ability to undergo evolutionary change. Cognitive…

神经元与认知 · 定量生物学 2026-01-12 Alexander Serov
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