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Advances in spatially-resolved transcriptomics (SRT) technologies have propelled the development of new computational analysis methods to unlock biological insights. As the cost of generating these data decreases, these technologies provide…

基因组学 · 定量生物学 2024-08-02 Boyi Guo , Wodan Ling , Sang Ho Kwon , Pratibha Panwar , Shila Ghazanfar , Keri Martinowich , Stephanie C. Hicks

Automatic segmentation of the prostate cancer from the multi-modal magnetic resonance images is of critical importance for the initial staging and prognosis of patients. However, how to use the multi-modal image features more efficiently is…

图像与视频处理 · 电气工程与系统科学 2020-11-10 Guokai Zhang , Xiaoang Shen , Ye Luo , Jihao Luo , Zeju Wang , Weigang Wang , Binghui Zhao , Jianwei Lu

Fusing intra-operative 2D transrectal ultrasound (TRUS) image with pre-operative 3D magnetic resonance (MR) volume to guide prostate biopsy can significantly increase the yield. However, such a multimodal 2D/3D registration problem is a…

图像与视频处理 · 电气工程与系统科学 2021-07-15 Hengtao Guo , Xuanang Xu , Sheng Xu , Bradford J. Wood , Pingkun Yan

A biopsy is the only diagnostic procedure for accurate histological confirmation of breast cancer. When sonographic placement is not feasible, a Magnetic Resonance Imaging(MRI)-guided biopsy is often preferred. The lack of real-time imaging…

Accuracy and precision of measurements are important for patient follow up in oncology but, unfortunately, partial volume effects introduce an undesired variability between observers. Super resolution techniques (SR) combine multiple…

医学物理 · 物理学 2015-06-25 Estanislao Oubel , Hubert Beaumont , Antoine Iannessi

Purpose: Magnetic resonance imaging (MRI) to visualize anatomical motion is becoming increasingly important when treating cancer patients with radiotherapy. Hybrid MRI-linear accelerator (MRI-linac) systems allow real-time motion management…

PURPOSE: Permanent breast seed implant (PBSI) using 103Pd is emerging as an effective adjuvant radiation technique for early-stage breast cancer. However, clinical dose evaluations follow the water-based TG-43 approach with its considerable…

The multi-modality imaging system offers optimal fused images for safe and precise interventions in modern clinical practices, such as computed tomography - ultrasound (CT-US) guidance for needle insertion. However, the limited dexterity…

机器人学 · 计算机科学 2025-02-18 Feng Li , Yuan Bi , Dianye Huang , Zhongliang Jiang , Nassir Navab

Medical image registration and segmentation are two of the most frequent tasks in medical image analysis. As these tasks are complementary and correlated, it would be beneficial to apply them simultaneously in a joint manner. In this paper,…

图像与视频处理 · 电气工程与系统科学 2021-05-06 Mohamed S. Elmahdy , Laurens Beljaards , Sahar Yousefi , Hessam Sokooti , Fons Verbeek , U. A. van der Heide , Marius Staring

Radiotherapy treatment planning is a challenging large-scale optimization problem plagued by uncertainty. Following the robust optimization methodology, we propose a novel, spatially based uncertainty set for robust modeling of radiotherapy…

最优化与控制 · 数学 2024-05-28 Noam Goldberg , Mark P. Langer , Shimrit Shtern

Magnetic resonance imaging (MRI) data is heterogeneous due to differences in device manufacturers, scanning protocols, and inter-subject variability. A conventional way to mitigate MR image heterogeneity is to apply preprocessing…

Prostate cancer, the second most prevalent male malignancy, requires advanced diagnostic tools. We propose an explainable AI system combining BERT (for textual clinical notes) and Random Forest (for numerical lab data) through a novel…

Glioma, the prevalent primary brain tumor, exhibits diverse aggressiveness levels and prognoses. Precise classification of glioma is paramount for treatment planning and predicting prognosis. This study aims to develop an algorithm to fuse…

图像与视频处理 · 电气工程与系统科学 2026-03-10 Kiranmayee Janardhan , Christy Bobby Thomas

Prostate cancer biopsy benefits from accurate fusion of transrectal ultrasound (TRUS) and magnetic resonance (MR) images. In the past few years, convolutional neural networks (CNNs) have been proved powerful in extracting image features…

计算机视觉与模式识别 · 计算机科学 2021-07-13 Xinrui Song , Hengtao Guo , Xuanang Xu , Hanqing Chao , Sheng Xu , Baris Turkbey , Bradford J. Wood , Ge Wang , Pingkun Yan

Purpose: Transurethral ultrasound therapy is an investigational treatment modality which could potentially be used for the localized treatment of prostate cancer. One of the limiting factors of this therapy is prostatic calcifications.…

Brain metastases are a complication of primary cancer, representing the most common type of brain tumor in adults. The management of multiple brain metastases represents a clinical challenge worldwide in finding the optimal treatment for…

图像与视频处理 · 电气工程与系统科学 2024-03-28 Ana Sofia Santos , Matheus Silva , Crystian Saraiva , José Soares , Victor Alves

Transrectal ultrasound (TRUS) imaging is a cost-effective and non-invasive modality widely used in the diagnosis of prostate cancer. The computer-aided diagnosis (CAD) relying on TRUS images has been extensively investigated recently.…

计算机视觉与模式识别 · 计算机科学 2026-04-27 Xu Lu , Qianhong Peng , Qihao Zhou , Shaopeng Liu , Xiuqin Ye , Chuan Yang , Yuan Yuan

This study aims to develop a digital twin (DT) framework to enhance adaptive proton stereotactic body radiation therapy (SBRT) for prostate cancer. Prostate SBRT has emerged as a leading option for external beam radiotherapy due to its…

The PI-CAI (Prostate Imaging: Cancer AI) challenge led to expert-level diagnostic algorithms for clinically significant prostate cancer detection. The algorithms receive biparametric MRI scans as input, which consist of T2-weighted and…

图像与视频处理 · 电气工程与系统科学 2024-07-01 Alessa Hering , Sarah de Boer , Anindo Saha , Jasper J. Twilt , Mattias P. Heinrich , Derya Yakar , Maarten de Rooij , Henkjan Huisman , Joeran S. Bosma

Artificial intelligence-based radiation therapy (RT) planning has the potential to reduce planning time and inter-planner variability, improving efficiency and consistency in clinical workflows. Most existing automated approaches rely on…