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Using Boolean networks as prototypical examples, the role of symmetry in the dynamics of heterogeneous complex systems is explored. We show that symmetry of the dynamics, especially in critical states, is a controlling feature that can be…

统计力学 · 物理学 2015-06-19 Shabnam Hossein , Matthew D. Reichl , Kevin E. Bassler

The co-evolution of network topology and dynamics is studied in an evolutionary Boolean network model that is a simple model of gene regulatory network. We find that a critical state emerges spontaneously resulting from interplay between…

统计力学 · 物理学 2007-05-23 Min Liu , Kevin E. Bassler

Boolean networks with canalizing functions are used to model gene regulatory networks. In order to learn how such networks may behave under evolutionary forces, we simulate the evolution of a single Boolean network by means of an adaptive…

种群与进化 · 定量生物学 2011-11-09 Agnes Szejka , Barbara Drossel

We investigate the evolution of populations of random Boolean networks under selection for robustness of the dynamics with respect to the perturbation of the state of a node. The fitness landscape contains a huge plateau of maximum fitness…

种群与进化 · 定量生物学 2009-11-13 Tamara Mihaljev , Barbara Drossel

Random Boolean networks have been used widely to explore aspects of gene regulatory networks. A modified form of the model through which to systematically explore the effects of increasing the number of gene states has previously been…

分子网络 · 定量生物学 2023-02-06 Larry Bull

Biological networks such as gene regulatory networks possess desirable properties. They are more robust and controllable than random networks. This motivates the search for structural and dynamical features that evolution has incorporated…

分子网络 · 定量生物学 2024-02-16 Claus Kadelka , David Murrugarra

Complex systems are often modeled as Boolean networks in attempts to capture their logical structure and reveal its dynamical consequences. Approximating the dynamics of continuous variables by discrete values and Boolean logic gates may,…

分子网络 · 定量生物学 2013-05-29 Johannes Norrell , Joshua E. S. Socolar

We study the effect of width on the dynamics of feature-learning neural networks across a variety of architectures and datasets. Early in training, wide neural networks trained on online data have not only identical loss curves but also…

机器学习 · 计算机科学 2023-12-07 Nikhil Vyas , Alexander Atanasov , Blake Bordelon , Depen Morwani , Sabarish Sainathan , Cengiz Pehlevan

Boolean networks are a popular modeling framework in computational biology to capture the dynamics of molecular networks, such as gene regulatory networks. It has been observed that many published models of such networks are defined by…

分子网络 · 定量生物学 2019-12-06 Elijah Paul , Gleb Pogudin , William Qin , Reinhard Laubenbacher

Boolean networks are special types of finite state time-discrete dynamical systems. A Boolean network can be described by a function from an n-dimensional vector space over the field of two elements to itself. A fundamental problem in…

定量方法 · 定量生物学 2013-07-03 Yi Ming Zou

We present and discuss the results of an experimental analysis in the design of Boolean networks by means of genetic algorithms. A population of networks is evolved with the aim of finding a network such that the attractor it reaches is of…

神经与进化计算 · 计算机科学 2011-02-01 Andrea Roli , Cristian Arcaroli , Marco Lazzarini , Stefano Benedettini

Since their introduction, Boolean networks have been traditionally studied in view of their rich dynamical behavior under different update protocols and for their qualitative analogy with cell regulatory networks. More recently, tools…

无序系统与神经网络 · 物理学 2007-05-23 Michele Leone , Andrea Pagnani , Giorgio Parisi , Osvaldo Zagordi

Diverse biological networks exhibit universal features distinguished from those of random networks, calling much attention to their origins and implications. Here we propose a minimal evolution model of Boolean regulatory networks, which…

分子网络 · 定量生物学 2014-11-26 Deok-Sun Lee

Boolean networks have been proposed as potentially useful models for genetic control. An important aspect of these networks is the stability of their dynamics in response to small perturbations. Previous approaches to stability have assumed…

分子网络 · 定量生物学 2015-05-13 Andrew Pomerance , Edward Ott , Michelle Girvan , Wolfgang Losert

We describe systems using Kauffman and similar networks. They are directed funct ioning networks consisting of finite number of nodes with finite number of discr ete states evaluated in synchronous mode of discrete time. In this paper we…

无序系统与神经网络 · 物理学 2009-11-13 Andrzej Gecow

Boolean networks model finite discrete dynamical systems with complex behaviours. The state of each component is determined by a Boolean function of the state of (a subset of) the components of the network. This paper addresses the…

人工智能 · 计算机科学 2020-02-28 Stéphanie Chevalier , Christine Froidevaux , Loïc Paulevé , Andrei Zinovyev

The brain's activity is characterized by the interaction of a very large number of neurons that are strongly affected by noise. However, signals often arise at macroscopic scales integrating the effect of many neurons into a reliable…

动力系统 · 数学 2012-11-07 Jonathan Touboul , G. Bard Ermentrout

We determine stability and attractor properties of random Boolean genetic network models with canalyzing rules for a variety of architectures. For all power law, exponential, and flat in-degree distributions, we find that the networks are…

分子网络 · 定量生物学 2007-05-23 Stuart Kauffman , Carsten Peterson , Björn Samuelsson , Carl Troein

We present a rigorous mathematical framework for analyzing dynamics of a broad class of Boolean network models. We use this framework to provide the first formal proof of many of the standard critical transition results in Boolean network…

无序系统与神经网络 · 物理学 2016-08-30 C. Seshadhri , Yevgeniy Vorobeychik , Jackson R. Mayo , Robert C. Armstrong , Joseph R. Ruthruff

We study the influence of stochastic effects due to finite population size in the evolutionary dynamics of populations interacting in the multi-person Prisoner's Dilemma game. This paper is an extension of the investigation presented in a…

种群与进化 · 定量生物学 2007-05-23 Anders Eriksson , Kristian Lindgren
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