相关论文: MAPK Cascades as Feedback Amplifiers
The behaviour of information cascades (such as retweets) has been modelled extensively. While point process-based generative models have long been in use for estimating cascade growths, deep learning has greatly enhanced diverse feature…
We report a new effect of a cascade replication of dissipative solitons from a single one. It is discussed in the framework of a common model based on the one-dimensional cubic-quintic complex Ginzburg-Landau equation in which an additional…
Biomolecular condensates organize biochemical processes by spatially concentrating molecules while allowing for dynamic exchange with their surroundings. However, transport across their interface can be strongly attenuated, leading to…
Damping typically results in attenuation of vibrations and elastic wave propagation in mechanical systems. Contrary to this conventional understanding, we demonstrate experimentally and explain theoretically the revival of an elastic wave…
This paper studies the mitigation of intersymbol interference in a diffusive molecular communication system using enzymes that freely diffuse in the propagation environment. The enzymes form reaction intermediates with information molecules…
Cortical microcircuits are very complex networks, but they are composed of a relatively small number of stereotypical motifs. Hence one strategy for throwing light on the computational function of cortical microcircuits is to analyze…
The immunological synapse is a patterned collection of different types of receptors and ligands that forms in the intercellular junction between T Cells and antigen presenting cells (APCs) during recognition. The synapse is implicated in…
Current scientific consensus holds that sound is transmitted, solely mechanically, from the tympanum to the cochlea via ossicles. However this theory does not explain the hearing extreme quality regarding high frequencies in mammals. So, we…
Convergence extension, the simultaneous elongation of tissue along one axis while narrowing along a perpendicular axis, occurs during embryonic development. A fundamental process that contributes to shaping the organism, it happens in many…
Glycosylation is a highly complex process to produce a diverse repertoire of cellular glycans that are attached to proteins and lipids. Glycans are involved in fundamental biological processes, including protein folding and clearance, cell…
Superconducting traveling-wave parametric amplifiers are a promising amplification technology suitable for applications in submillimeter astronomy. Their implementation relies on the use of Floquet transmission lines in order to create…
Tipping points are critical thresholds of parameters where tiny perturbations can lead to abrupt and large qualitative changes in the systems. Many real-world systems that exhibit tipping behavior can be represented as networks of…
Biological oscillators coordinate individual cellular components so that they function coherently and collectively. They are typically composed of multiple feedback loops, and period mismatch is unavoidable in biological implementations. We…
The activities and interactions of proteins that govern the cellular response to a signal generate a multitude of protein phosphorylation states and heterogeneous protein complexes. Here, using a computational model that accounts for 307…
Active and passive scalars transported by an incompressible two-dimensional conductive fluid are investigated. It is shown that a passive scalar displays a direct cascade towards the small scales while the active magnetic potential builds…
Biomolecular condensates composed of intrinsically disordered proteins (IDPs) are vital for proper cellular function, and their dysfunction is associated with diseases including neurodegeneration and cancer. Despite their biological…
An autoencoder-based codec employs quantization to turn its bottleneck layer activation into bitstrings, a process that hinders information flow between the encoder and decoder parts. To circumvent this issue, we employ additional skip…
We investigate how to exploit intermittent feedback for interference management. Focusing on the two-user linear deterministic interference channel, we completely characterize the capacity region. We find that the characterization only…
Feedback connections play a prominent role in the human brain but have not received much attention in artificial neural network research. Here, a biologically inspired feedback mechanism which gates rectified linear units is proposed. On…
Many neural systems display cascading behavior characterized by uninterrupted sequences of neuronal firing. This gap precludes an understanding of how variations in network structure manifest in neural dynamics and either support or impinge…