相关论文: Node similarity within subgraphs of protein intera…

Our Microbiome Network Alignment Algorithm (MiNAA) aligns two microbial networks using a combination of the GRAph ALigner (GRAAL) algorithm and the Hungarian algorithm. Network alignment algorithms find pairs of nodes (one node from the…

Link prediction plays an important role in understanding intrinsic evolving mechanisms of networks. With the belief that the likelihood of the existence of a link between two nodes is strongly related with their similarity, many methods…

In this article, we revisit and expand our prior work on graph similarity. As with our earlier work, we focus on a view of similarity which does not require node correspondence between graphs under comparison. Our work is suited to the…

Homophily -- the tendency of nodes to connect to others of the same type -- is a central issue in the study of networks. Here we take a local view of homophily, defining notions of first-order homophily of a node (its individual tendency to…

Summary: Most cellular tasks are performed not by individual proteins, but by groups of functionally associated proteins, often referred to as modules. In a protein assocation network modules appear as groups of densely interconnected…

PPI network alignment aims to find topological and functional similarities between networks of different species. Several alignment approaches have been proposed. Each of these approaches relies on a different alignment method and uses…

Network node similarity measure has been paid particular attention in the field of statistical physics. In this paper, we utilize the concept of information and information loss to measure the node similarity. The whole model is based on…

Protein-protein interactions (PPIs) play key roles in a broad range of biological processes. Numerous strategies have been proposed for predicting PPIs, and among them, graph-based methods have demonstrated promising outcomes owing to the…

Motifs are patterns of subgraphs of complex networks. We studied the impact of such patterns of connectivity on the level of correlated, or synchronized, spiking activity among pairs of cells in a recurrent network model of integrate and…

In this work, we propose a novel centrality metric, referred to as star centrality, which incorporates information from the closed neighborhood of a node, rather than solely from the node itself, when calculating its topological importance.…

We consider the problem of testing whether a graph's degree distribution belongs to a particular family, such as poisson or scale-free, given that we only observe a sampled subgraph. In particular, we focus on induced subgraph sampling, a…

Proteins participating in a protein-protein interaction network can be grouped into homology classes following their common ancestry. Proteins added to the network correspond to genes added to the classes, so that the dynamics of the two…

Successive whole genome duplications have recently been firmly established in all major eukaryote kingdoms. It is not clear, however, how such dramatic evolutionary process has contributed to shape the large scale topology of…

Accurately predicting complex protein-protein interactions (PPIs) is crucial for decoding biological processes, from cellular functioning to disease mechanisms. However, experimental methods for determining PPIs are computationally…

In this paper, we consider the statistical analysis of a protein interaction network. We propose a Bayesian model that uses a hierarchy of probabilistic assumptions about the way proteins interact with one another in order to: (i) identify…

Graph matching, also known as network alignment, refers to finding a bijection between the vertex sets of two given graphs so as to maximally align their edges. This fundamental computational problem arises frequently in multiple fields…

The problem of link prediction, predicting if two nodes in a network have a connection between them, is a theoretical problem with numerous field-agnostic real-world applications. This paper investigates the efficacy of three classes of…

Measure the similarity of the nodes in the complex networks have interested many researchers to explore it. In this paper, a new method which is based on the degree centrality and the Relative-entropy is proposed to measure the similarity…

Analogical reasoning depends fundamentally on the ability to learn and generalize about relations between objects. We develop an approach to relational learning which, given a set of pairs of objects…

Analysing and explaining relationships between entities in a graph is a fundamental problem associated with many practical applications. For example, a graph of biological pathways can be used for discovering a previously unknown…