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We consider the analysis of continuous repeated measurement outcomes that are collected through time, also known as longitudinal data. A standard framework for analysing data of this kind is a linear Gaussian mixed-effects model within…

统计方法学 · 统计学 2018-04-10 Özgür Asar , David Bolin , Peter J. Diggle , Jonas Wallin

Longitudinal biomarker data and health outcomes are routinely collected in many studies to assess how biomarker trajectories predict health outcomes. Existing methods primarily focus on mean biomarker profiles, treating variability as a…

Many epidemiological and clinical studies aim at analyzing a time-to-event endpoint. A common complication is right censoring. In some cases, it arises because subjects are still surviving after the study terminates or move out of the study…

统计方法学 · 统计学 2024-01-10 Andrew Ying

In this article, the analysis of left truncated and right censored competing risks data is carried out, under the assumption of the latent failure times model. It is assumed that there are two competing causes of failures, although most of…

统计方法学 · 统计学 2020-08-19 Debasis Kundu , Debanjan Mitra , Ayon Ganguly

Joint modelling of longitudinal observations and event times continues to remain a topic of considerable interest in biomedical research. For example, in HIV studies, the longitudinal bio-marker such as CD4 cell count in a patient's blood…

统计方法学 · 统计学 2024-07-19 Srimanti Dutta , Arindom Chakraborty , Dipankar Bandyopadhyay

Interval censored data commonly arise in medical studies when the event time of interest is only known to lie within an interval. In the presence of a cure subgroup, conventional mixture cure models typically assume a logistic model for the…

统计方法学 · 统计学 2026-01-21 Xiaoru Huang , Tonghui Yu , Xiaoyu Liu

In active surveillance of prostate cancer, cancer progression is interval-censored and the examination to detect progression is subject to misclassification, usually false negatives. Meanwhile, patients may initiate early treatment before…

Measurement error arises commonly in clinical research settings that rely on data from electronic health records or large observational cohorts. In particular, self-reported outcomes are typical in cohort studies for chronic diseases such…

统计方法学 · 统计学 2021-02-08 Lillian A. Boe , Lesley F. Tinker , Pamela A. Shaw

This paper introduces the R package INLAjoint, designed as a toolbox for fitting a diverse range of regression models addressing both longitudinal and survival outcomes. INLAjoint relies on the computational efficiency of the integrated…

统计方法学 · 统计学 2024-04-04 Denis Rustand , Janet van Niekerk , Elias Teixeira Krainski , Håvard Rue

Combating bias in NLP requires bias measurement. Bias measurement is almost always achieved by using lexicons of seed terms, i.e. sets of words specifying stereotypes or dimensions of interest. This reproducibility study focuses on the…

计算与语言 · 计算机科学 2022-06-07 Jille van der Togt , Lea Tiyavorabun , Matteo Rosati , Giulio Starace

Nonparametric and semiparametric methods are commonly used in survival analysis to mitigate the bias due to model misspecification. However, such methods often cannot estimate upper-tail survival quantiles when a sizable proportion of the…

统计方法学 · 统计学 2019-07-19 Yifan Wang , Tian You , Martin Lysy

Linear mixed-effects models are a central analytical tool for modeling hierarchical and longitudinal data, as they allow simultaneous representation of fixed and random sources of variation. In practice, inference for such models is most…

统计方法学 · 统计学 2026-02-12 Hilde Vinje , Lars Erik Gangsei

Finite mixture distributions arise in sampling a heterogeneous population. Data drawn from such a population will exhibit extra variability relative to any single subpopulation. Statistical models based on finite mixtures can assist in the…

统计方法学 · 统计学 2024-01-19 Andrew M. Raim , Nagaraj K. Neerchal , Jorge G. Morel

This paper proposes the asymmetric linear double autoregression, which jointly models the conditional mean and conditional heteroscedasticity characterized by asymmetric effects. A sufficient condition is established for the existence of a…

统计方法学 · 统计学 2021-04-22 Songhua Tan , Qianqian Zhu

This report is designed to clarify a few points about the article "Semiparametric modeling of grouped current duration data with preferential reporting" by McLain, Sundaram, Thoma and Louis in Statistics in Medicine (McLain et al., 2014,…

应用统计 · 统计学 2018-01-03 Alexander C. McLain , Rajeshwari Sundaram , Marie Thoma , Germaine M. Buck Louis

In this paper, we propose two variable selection methods for adjusting the censoring information for survival times, such as the restricted mean survival time. To adjust for the influence of censoring, we consider an inverse survival…

统计方法学 · 统计学 2022-12-06 Masahiro Kojima

This article considers the automatic selection problem of the relevant explanatory variables in a right-censored model on a massive database. We propose and study four aggregated censored adaptive LASSO estimators constructed by dividing…

统计理论 · 数学 2025-02-04 Gabriela Ciuperca

A novel data-driven methodology is presented for the joint selection of prior parameters for both fixed and random effects in Linear Mixed Models (LMMs). This approach facilitates the estimation of complex random-effects structures, as well…

统计方法学 · 统计学 2026-04-28 Matteo Amestoy , R. Vermeulen , Mark A. van de Wiel , Wessel N. van Wieringen

When data are collected subject to a detection limit, observations below the detection limit may be considered censored. In addition, the domain of such observations may be restricted; for example, values may be required to be non-negative.…

应用统计 · 统计学 2020-06-30 Justin R. Williams , Hyung-Woo Kim , Catherine M. Crespi

In many fields of study, we only observe lower bounds on the true response value of some experiments. When fitting a regression model to predict the distribution of the outcomes, we cannot simply drop these right-censored observations, but…

人工智能 · 计算机科学 2020-09-30 Katharina Eggensperger , Kai Haase , Philipp Müller , Marius Lindauer , Frank Hutter