统计方法学
Circular biomarkers arise naturally in many biomedical applications, particularly in ophthalmology, where angular measurements such as astigmatism are routinely recorded. Similar directional variables also occur in the study of human body…
Balancing covariates is critical for credible and efficient randomized experiments. Rerandomization addresses this by repeatedly generating treatment assignments until covariate balance meets a prespecified threshold. By shrinking this…
It is a common practice in randomized clinical trials with the standard survival outcome to follow patients until a prespecified number of events have been observed, a type of trial known as the event-driven trial. The event-driven design…
Choosing relevant predictors is central to the analysis of biomedical time-to-event data. Classical frequentist inference, however, presumes that the set of covariates is fixed in advance and does not account for data-driven variable…
Stochastic processes are a flexible and widely used family of models for statistical modeling. While stochastic processes offer attractive properties such as inclusion of uncertainty properties, their inference is typically intractable,…
In the setting of multi-armed trials, adaptive designs are a popular way to increase estimation efficiency, identify optimal treatments, or maximize rewards to individuals. Recent work has considered the case of estimating the effects of K…
In the study of heavy tail data, several models have been introduced. If the interest is in the tail of the distribution, block maxima or excess over thresholds are the typical approaches, wasting relevant information in the bulk of the…
We propose a framework for computing, optimizing and integrating with respect to a smooth marginal likelihood in statistical models that involve high-dimensional parameters/latent variables and continuous low-dimensional hyperparameters.…
We study the problem of offline changepoint localization in a distribution-free setting. One observes a vector of data with a single changepoint, assuming that the data before and after the changepoint are iid (or more generally…
The problem of combining multiple forecasts of related quantities that obey expected equality and additivity constraints, often referred to a hierarchical forecast reconciliation, is naturally stated as a simple optimization problem. In…
We introduce a new class of range restricted formal data privacy standards that condition on owner beliefs about sensitive data ranges. By incorporating this additional information, we can provide a stronger privacy guarantee (e.g. an…
In this paper, we consider the problem of estimating Tsallis entropy from a given data set. We propose four different estimators for Tsallis entropy measure based on higher-order sample spacings, and then discuss estimation of Tsallis…
For many conditions, it is of clinical importance to know not just the ability of a test to distinguish between those with and without the disease, but also the sensitivity to detect disease at different stages: in particular, the test's…
Instrumental variable methods are fundamental to causal inference when treatment assignment is confounded by unobserved variables. In this article, we develop a general nonparametric causal framework for identification and learning with…
The Eilers-Whittaker method for data smoothing effectiveness depends on the choice of the regularisation parameter, and automatic selection is a necessity for large datasets. Common methods, such as leave-one-out cross-validation, can…
When data are collected adaptively, such as in bandit algorithms, classical statistical approaches such as ordinary least squares and $M$-estimation will often fail to achieve asymptotic normality. Although recent lines of work have…
Multi-source and multi-modal datasets are increasingly common in scientific research, yet they often exhibit block-wise missingness, where entire modalities are systematically absent in some sources or no single source contains all…
High-dimensional vector autoregressive (VAR) models offer a versatile framework for multivariate time series analysis, yet face critical challenges from over-parameterization and uncertain lag order. In this paper, we systematically compare…
The impact of wildfire smoke on air quality is a growing concern, contributing to air pollution through a complex mixture of chemical species with important implications for public health. While previous studies have primarily focused on…
We introduce a new cross-validation method based on an equicorrelated Gaussian randomization scheme. Our method is well-suited for problems where sample splitting is infeasible, either because the data violate the assumption of independent…