种群与进化
In many social mammals, early life social adversity and social integration largely predict individual health, lifespan and reproductive success. Efforts in identifying the physiological mechanisms mediating the relationship between the…
We developed a simple mathematical model to describe criminality and the justice system composed of the police investigation and court trial. The model assessed two features of organized crime -- the cost-benefit analysis done by the…
We consider a general class of Markovian models describing the growth in a randomly fluctuating environment of a clonal biological population having several phenotypes related by stochastic switching. Phenotypes differ e.g. by the level of…
We explore the relationship between Eulerian and Lagrangian approaches for modeling movement in vector-borne diseases for discrete space. In the Eulerian approach we account for the movement of hosts explicitly through movement rates…
We study species abundance in the empirical plant-pollinator mutualistic networks exhibiting broad degree distributions, with uniform intra-group competition assumed, by the Lotka-Volterra equation. The stability of a fixed point is found…
Ecologists have put forward many explanations for coexistence, but these are only partial explanations; nature is complex, so it is reasonable to assume that in any given ecological community, multiple mechanisms of coexistence are…
In this paper, we discuss the conceptual underpinnings of Modern Coexistence Theory (MCT), a quantitative framework for understanding ecological coexistence. In order to use MCT to infer how species are coexisting, one must relate a complex…
Rapid antigen tests detect proteins at the surface of virus particles, identifying the disease during its infectious phase. In contrast, PCR tests detect viral genomes; they can thus diagnose COVID-19 before the infectious phase but also…
Chimeric antigen receptor (CAR) T-cell based immunotherapy has shown its potential in treating blood cancers, and its application to solid tumors is currently being extensively investigated. For glioma brain tumors, various CAR T-cell…
Phenomenological and deterministic models are often used for the estimation of transmission parameters in an epidemic and for the prediction of its growth trajectory. Such analyses are usually based on single peak outbreak dynamics. In…
The metabolic activity of microbes has played an essential role in the evolution and persistence of life on Earth. Microbial metabolism plays a primary role in the flow of carbon, nitrogen and other elements through the biosphere on a…
The evolutionary relationships among organisms have traditionally been represented using rooted phylogenetic trees. However, due to reticulate processes such as hybridization or lateral gene transfer, evolution cannot always be adequately…
SIRS models capture transmission dynamics of infectious diseases for which immunity is not lifelong. Extending these models by a W compartment for individuals with waning immunity, the boosting of the immune system upon repeated exposure…
The storage effect is a general explanation for coexistence in a variable environment. The generality of the storage effect is both a strength - it can be quantified in many systems - and a challenge - there is not a clear relationship…
How do species coexist? A framework known as Modern Coexistence Theory measures mechanisms of coexistence by comparing a species perturbed to low density (the invader) to other species that remain at their typical densities (the residents);…
Since December 2020, variants of COVID-19 (especially Delta and Omicron) appeared with different characteristics that influenced death and transmissibility emerged around the world. To address the novel dynamics of the disease, we propose a…
The existing concept of the "fitness value of information" provides a theoretical upper bound on the fitness advantage of using information concerning a fluctuating environment. Using concepts from rate-distortion theory, we develop a…
Non-equilibrium thermodynamics has long been an area of substantial interest to ecologists because most fundamental biological processes, such as protein synthesis and respiration, are inherently energy-consuming. Microbial communities are…
Population-wide vaccination is critical for containing the SARS-CoV-2 (Covid-19) pandemic when combined with restrictive and prevention measures. In this study, we introduce SAIVR, a mathematical model able to forecast the Covid-19 epidemic…
Strategies adopted globally to mitigate the threat of COVID-19 have primarily involved lockdown measures with substantial economic and social costs with varying degrees of success. Morbidity patterns of COVID-19 variants have a strong…