神经元与认知
Adaptive behavior emerges through a dynamic interaction between cognitive agents and changing environmental demands. The investigation of information processing underlying adaptive behavior relies on controlled experimental settings in…
The mechanisms underlying how activity in the visual pathway may give rise through neural plasticity to many of the features observed experimentally in the early stages of visual processing was provided by Linkser in a seminal, three-paper…
Interaction of electromagnetic (EM) waves with human tissue has been a longstanding research topic for electrical and biomedical engineers. However, few numbers of publications discuss the impacts of external EM-waves on neural stimulation…
For almost two decades schizophrenia has been considered to be a functional disconnection disorder. This functional disconnectivity between several brain regions could have a neurodevelopmental origin. Various approaches suggest the ventral…
Large, open-source consortium datasets have spurred the development of new and increasingly powerful machine learning approaches in brain connectomics. However, one key question remains: are we capturing biologically relevant and…
Experimental and numerical results suggest that the brain can be viewed as a system acting close to a critical point, as confirmed by scale-free distributions of relevant quantities in a variety of different systems and models. Less…
The simplicity principle states that the human visual system prefers the simplest interpretation. However, conventional coding models could not resolve the incompatibility between predictions from the global minimum principle and the local…
Functional connectivity quantifies the statistical dependencies between the activity of brain regions, measured using neuroimaging data such as functional MRI BOLD time series. The network representation of functional connectivity, called a…
Tracking the positions of objects in local space is a core function of animal brains. We do not yet understand how it is done with limited neural resources. The challenges of spatial cognition are discussed under the criteria: (a) scaling…
Experiments have shown that the same stimulation pattern that causes Long-Term Potentiation in proximal synapses, will induce Long-Term Depression in distal ones. In order to understand these, and other, surprising observations we use a…
Individuals differ in the time it takes to produce words when naming a picture. However, it is unknown whether this inter-individual variability emerges in earlier stages of word production (e.g., lexical selection) or later stages (e.g.,…
We analyse the neural dynamics and its relation with the emergent behaviour of a robotic vehicle that is controlled by a neural network numerical simulation based on the nervous system of the nematode Caenorhabditis elegans. The robot…
We present a novel methodology to enable control of a neuromorphic circuit in close analogy with the physiological neuromodulation of a single neuron. The methodology is general in that it only relies on a parallel interconnection of…
The contributions of independent noise sources to the variability of action potential timing has not previously been studied at the level of individual directed molecular transitions within a conductance-based model ion-state graph. The…
Background: Direct electrical stimulation of the brain through intracranial electrodes is currently used to probe the epileptic brain as part of pre-surgical evaluation, and it is also being considered for therapeutic treatments through…
Fox and Lu introduced a Langevin framework for discrete-time stochastic models of randomly gated ion channels such as the Hodgkin-Huxley (HH) system. They derived a Fokker-Planck equation with state-dependent diffusion tensor $D$ and…
Electrical stimulation of neural systems is a key tool for understanding neural dynamics and ultimately for developing clinical treatments. Many applications of electrical stimulation affect large populations of neurons. However,…
Extracellular electrical potentials (EEP) recorded from the brain are an active manifestation of all cellular processes that propagate within a volume of brain tissue. A standard approach for their quantification are power spectral analyses…
The advancement of single cell RNA-sequencing technologies has led to an explosion of cell type definitions across multiple organs and organisms. While standards for data and metadata intake are arising, organization of cell types has…
The study of neuronal interactions is currently at the center of several big collaborative neuroscience projects (including the Human Connectome Project, the Blue Brain Project, the Brainome, etc.) which attempt to obtain a detailed map of…