神经元与认知
The way we view the reality of nature, including ourselves, depend on consciousness.It also defines the identity of the person, since we know people in terms of their experiences. In general, consciousness defines human existence in this…
A deep understanding of the dynamics of the human nervous system requires the simultaneous study of multiple spatiotemporal scales from the level of neurotransmitters up to the level of human cultures. This is likely impossible for…
Consciousness is a sequential process of awareness which can focus on one piece of information at a time. This process of awareness experiences causation which underpins the notion of time while it interplays with matter and energy, forming…
A new brain model is introduced, based on the Impulse Pattern Formulation (IPF) already established for modeling and understanding musical instrument and rhythm perception and production. It assumes the brain works with impulses, neural…
Mapping spatial distributions of transcriptomic cell types is essential to understanding the brain, with its exceptional cellular heterogeneity and the functional significance of its spatial organization. Spatial transcriptomics techniques…
Nowadays, we have witnessed the great success of AI in various applications, including image classification, game playing, protein structure analysis, language translation, and content generation. Despite these powerful applications, there…
Functional magnetic resonance imaging (fMRI) has been widely utilized to study the motor deficits and rehabilitation following stroke. In particular, functional connectivity(FC) analyses with fMRI at rest can be employed to reveal the…
Processing faces accurately and efficiently is a key capability of humans and other animals that engage in sophisticated social tasks. Recent studies reported a decoupled coding for faces in the primate inferotemporal cortex, with two…
Temporal-lobe epilepsy in humans is often associated with widespread, synchronized neuron firing that co-occurs with traveling waves in local field potential. These traveling waves generate stochastic oscillations in a time series of…
Olfactory navigation is observed across species and plays a crucial role in locating resources for survival. In the laboratory, understanding the behavioral strategies and neural circuits underlying odor-taxis requires a detailed…
Self-supervised learning techniques are celebrating immense success in natural language processing (NLP) by enabling models to learn from broad language data at unprecedented scales. Here, we aim to leverage the success of these techniques…
The discovery of place cells and other spatially modulated neurons in the hippocampal complex of rodents has been crucial to elucidating the neural basis of spatial cognition. More recently, the replay of neural sequences encoding…
The spectacular successes of recurrent neural network models where key parameters are adjusted via backpropagation-based gradient descent have inspired much thought as to how biological neuronal networks might solve the corresponding…
Synaptic communication is studied by communication engineers for two main reasons. One is to enable novel neuroengineering applications that require interfacing with neurons. The other reason is to draw inspiration for the design of…
Young immature granule cells (imGCs) appear via adult neurogenesis in the hippocampal dentate gyrus (DG). In comparison to mature GCs (mGCs) (born during development), the imGCs exhibit two competing distinct properties such as high…
The standard approach to modeling the human brain as a complex system is with a network, where the basic unit of interaction is a pairwise link between two brain regions. While powerful, this approach is limited by the inability to assess…
Computational psychiatry is a field aimed at developing formal models of information processing in the human brain, and how alterations in this processing can lead to clinical phenomena. Despite significant progress in the development of…
Classical good continuation for image curves is based on $2D$ position and orientation. It is supported by the columnar organization of cortex, by psychophysical experiments, and by rich models of (differential) geometry. Here we extend…
Hearing loss is a major health problem and psychological burden in humans. Mouse models offer a possibility to elucidate genes involved in the underlying developmental and pathophysiological mechanisms of hearing impairment. To this end,…
Many surface cues support three-dimensional shape perception, but people can sometimes still see shape when these features are missing -- in extreme cases, even when an object is completely occluded, as when covered with a draped cloth. We…