医学物理
MRI-guided radiation treatment planning is widely applied because of its superior soft-tissue contrast and no ionization radiation compared to CT-based planning. In this regard, synthetic CT (sCT) images should be generated from the…
Multicomponent T2-mapping using a gradient and spin-echo (GraSE) acquisition has become standard for myelin water imaging at 3T. Higher magnetic field strengths promise SNR benefits but face specific absorption rate limits and shortened T2…
Blunt traumatic aortic rupture is a heart injury that can occur in falls, automobile accidents, and sporting injuries involving impact to the thorax. Despite its severity and high morbidity rate, the research still does not provide a…
Positron emission tomography, like many other tomographic imaging modalities, relies on an image reconstruction step to produce cross-sectional images from projection data. Detection and localization of the back-to-back annihilation photons…
Purpose: To implement and evaluate a sequential approach to obtain semi-quantitative T1-weighted MPRAGE images, unbiased by B1 inhomogeneities at 7T. Methods: In the reference gradient echo used for normalization of the MPRAGE image, flip…
This study aims at revealing the effect of composition on mechanical and antibacterial properties of hydroxyapatite/gray Titania coating for biomedical applications. HAp is a bioceramic material used as a plasma-sprayed coating to promote…
Inter-observer variation is a significant problem in clinical target volume(CTV) segmentation in postoperative settings, where there is no gross tumor present. In this scenario, the CTV is not an anatomically established structure, but one…
Clinically useful proton Computed Tomography images will rely on algorithms to find the three-dimensional proton stopping power distribution that optimally fits the measured proton data. We present a least squares iterative method with many…
Beam angle optimization (BAO) largely determines the performance of fixed-field intensity modulated radiation therapy (IMRT), and it is usually considered as non-convex optimization and an NP hard problem. In this work, BAO is reformulated…
Salicylic acid (SA) is a primary phytohormone released in response to stress, particularly biotic infections in plants. Monitoring SA levels may provide a way for early disease detection in crops providing a way for applying effective…
This article presents the conceptual design of a new compact superconducting gantry and synchrotron for Carbon ion therapy and focuses on the solutions (layout and optics) to make it compact. The main specificity of this gantry design is to…
Many tools exist for the quantification of GABA-edited magnetic resonance spectroscopy (MRS) data. Despite a recent consensus effort by the MRS community, literature comparing them is sparse but indicates a methodological bias. While invivo…
Given the long subclinical stage of Alzheimer's disease (AD), the study of biomarkers is relevant both for early diagnosis and the fundamental understanding of the pathophysiology of AD. Biomarkers provided by…
Diffusion pore imaging is an extension of diffusion-weighted nuclear magnetic resonance imaging enabling the direct measurement of the shape of arbitrarily formed, closed pores by probing diffusion restrictions using the motion of…
This paper presents a novel approach on solving the phase problem in nuclear magnetic resonance (NMR) diffusion pore imaging, a method, which allows imaging the shape of arbitrary closed pores filled with an NMR-detectable medium for…
$\bf{Purpose:}$ The goal of this study was (i) to use artificial intelligence to automate the traditionally labor-intensive process of manual segmentation of tumor regions in pathology slides performed by a pathologist and (ii) to validate…
An approach to reduce motion artifacts in Quantitative Susceptibility Mapping using deep learning is proposed. We use an affine motion model with randomly created motion profiles to simulate motion-corrupted QSM images. The simulated QSM…
Background: Studies on intravoxel incoherent motion (IVIM) imaging are carried out with different acquisition protocols. Purpose: Investigate the dependence of IVIM parameters on the B_0field strength when using a bi- or triexponential…
Recent study reported that an aerosolised virus (COVID-19) can survive in the air for a few hours. It is highly possible that people get infected with the disease by breathing and contact with items contaminated by the aerosolised virus.…
Purpose: A supervised learning framework is proposed to automatically generate MR sequences and corresponding reconstruction based on the target contrast of interest. Combined with a flexible, task-driven cost function this allows for an…