医学物理
When a macroscopic-sized non-crystalline sample is illuminated using coherent x-ray radiation, a bifurcation of photon energy flow may occur. The coarse-grained complex refractive index of the sample may be considered to attenuate and…
TCP models based on Poisson statistics are characterizing the distribution of the surviving clonogens. It enables the calculation of TCP for individuals. In order to describe clinically observed survival data of patient cohorts it is…
A method for extracting the dark-field signal in propagation-based phase-contrast imaging is proposed. In the case of objects consisting predominantly of a single material, or several different materials with similar ratios of the real…
$\textbf{Purpose:}$ To quantify the effectiveness of EPID-based cine transmission dosimetry to detect gross patient anatomic errors. $\textbf{Method and Materials:}$ EPID image frames resulting from fluence transmitted through multiple…
Purpose: Anthropomorphic phantoms can be used in radiotherapy to confirm dose distributions. In this work, a prototype phantom with a deformable chest wall was created based on real human. Methods: A technique similar to 3-dimensional…
Purpose: This study extends the Fast ROtary Nonlinear Spatial ACquisition (FRONSAC) method to include 3D acquisitions and reconstructions. It also presents a transform domain reconstruction that makes 3D reconstructions practical and…
Effective and accurate in-vivo diagnosis of retinal pathologies requires high performance imaging devices, combining a large field of view and the ability to discriminate the ballistic signal from the diffuse background in order to provide…
A tomographic technique called full-waveform inversion has recently shown promise as a fast, affordable, and safe modality to image the brain using ultrasound. However, its high computational cost and memory footprint currently limit its…
In this preliminary study technical methodology for kinematic tracking and profiling of wrist carpal bones during unconstrained movements is explored. Heavily under-sampled and fat-saturated 3D Cartesian MRI acquisition were used to capture…
Diffusing Alpha-emitters Radiation Therapy (DaRT) is a new method for treating solid tumors using alpha particles. Unlike conventional radiotherapy, where the physical models for dose calculations are known and routinely used, for DaRT a…
There is increasing evidence that infection with SARS-CoV-2 can cause a spectrum of neurological symptoms. In this paper, we develop a theoretical concept underlying such neurological COVID-19 consequences by employing a non-equilibrium…
A classification of the tasks of human thermoregulation is proposed, which allows combining various scientific studies into one system, which takes into account environmental factors, biological feedback in the body and different properties…
The determination of relative stopping power (RSP) via proton computed tomography (pCT) of a patient is dependent in part on the knowledge of the incoming proton kinetic energies; the uncertainty in these energies is in turn determined by…
This paper proposes a semi-automatic system based on quantitative characterization of the specific image patterns in lung ultrasound (LUS) images, in order to assess the lung conditions of patients with COVID-19 pneumonia, as well as to…
CT perfusion imaging (CTP) plays an important role in decision making for the treatment of acute ischemic stroke with large vessel occlusion. Since the CT perfusion scan time is approximately one minute, the patient is exposed to a…
Tracking and characterizing the blood uptake process within solid pancreatic tumors and the subsequent spatio-temporal distribution of red blood cells are critical to the clinical diagnosis of the cancer. This systematic computational study…
While experimentation with synthetic stimuli in abstracted listening situations has a long standing and successful history in hearing research, an increased interest exists on closing the remaining gap towards real-life listening by…
The loss of melanized neurons in the substantia nigra pars compacta is a primary feature in Parkinson's disease (PD). Iron deposition occurs in conjunction with this loss. Loss of nigral neurons should remove barriers for diffusion and…
Design and characterisation of capsules is not an easy task owing to the multiple involved preparation factors and parameters. Here, a novel method to characterise capsule membrane permeability to solute molecules by an inverse approach is…
In this work we investigate viral load propagation due to liquid droplets expelled during respiratory actions. We describe a mechanism of the transmission of such evaporating system and analyze dependence on several ambient parameters for…