医学物理
Timely diagnosis of breast cancer is an important task. This type of breast cancer is one of the most common diseases. The method of microwave radiothermometry is a promising direction for solving this problem. The method is based on…
Deep image prior (DIP) has recently attracted attention owing to its unsupervised positron emission tomography (PET) image reconstruction, which does not require any prior training dataset. In this paper, we present the first attempt to…
Purpose: To substantially shorten the acquisition time required for quantitative 3D chemical exchange saturation transfer (CEST) and semisolid magnetization transfer (MT) imaging and allow for rapid chemical exchange parameter map…
In this work the development of a machine learning-based Reduced Order Model (ROM) for the investigation of hemodynamics in a patient-specific configuration of Coronary Artery Bypass Graft (CABG) is proposed. The computational domain is…
Electromagnetic tracking (EMT) shows great potential for automating implant reconstruction in brachytherapy. One of the challenges of this technology is that it does not intrinsically share the same reference frame as the patient's medical…
In biomedical research and the practice of cancer therapy, gold nanoparticles have been used to visualize malignant tumors, as the heated bodies for hyperthermia of cancer cells, as drug carriers to deliver drugs to a cancer cell, but, to…
Significance: Diffuse in-vivo Flow Cytometry (DiFC) is an emerging fluorescence sensing method to non-invasively detect labeled circulating cells in-vivo. However, due to Signal-to-Noise Ratio (SNR) constraints largely attributed to…
Background: Respiratory-resolved four-dimensional magnetic resonance imaging (4D-MRI) provides essential motion information for accurate radiation treatments of mobile tumors. However, obtaining high-quality 4D-MRI suffers from long…
Dual-energy computed tomography (DECT) is a promising technology that has shown a number of clinical advantages over conventional X-ray CT, such as improved material identification, artifact suppression, etc. For proton therapy treatment…
In photoacoustic computed tomography (PACT) with short-pulsed laser excitation, wideband acoustic signals are generated in biological tissues with frequencies related to the effective shapes and sizes of the optically absorbing targets.…
The clinical application of patient-specific modelling of the heart can provide valuable insights in supplementing and advancing methods of diagnosis as well as helping to devise the best possible therapeutic approach for each individual…
A phase-field model is developed to simulate the corrosion of Mg alloys in body fluids. The model incorporates both Mg dissolution and the transport of Mg ions in solution, naturally predicting the transition from activation-controlled to…
Purpose: This study proposes a systematic method for determining the optimal x-ray tube settings/energy windows and fluence for minimal noise and maximum CNR in material density images obtained from DECT scans by fixing the subject size and…
Raman spectroscopy can provide insight into the molecular composition of cells and tissue. Consequently, it can be used as a powerful diagnostic tool, e.g. to help identify changes in molecular contents with the onset of disease. But robust…
Speckle-based phase-contrast X-ray imaging (SB-PCXI) can reconstruct high-resolution images of weakly-attenuating materials that would otherwise be indistinguishable in conventional attenuation-based imaging. The experimental setup of…
Propagation-based phase-contrast X-ray imaging (PB-PCXI) generates image contrast by utilizing sample-imposed phase-shifts. This has proven useful when imaging weakly-attenuating samples, as conventional attenuation-based imaging does not…
The challenge of removing cancerous cells lies in the limitation of organ at risk, which restricts the ability to increase the radiation dose adequately for enhancing treatment effectiveness. This survey provides a comprehensive overview of…
Advances in material design has led to the rapid development of novel materials with increasing complexity and functions in bioengineering. In particular, functionally graded materials (FGMs) offer important advantages in various fields of…
Differentiation of breast tissues is challenging in X-ray imaging because tissues might share similar or even the same linear attenuation coefficients $\mu$. Spectral computed tomography (CT) allows for more quantitative characterization in…
We aim to investigate the feasibility of online monitoring of irradiation time (IRT) and scan time for FLASH radiotherapy using a pixelated semiconductor detector. Measurements of the time structure of FLASH irradiations were performed…