医学物理
We report on the first systematic characterisation of a tuneable laser-driven electron source capable of delivering Gy-scale doses in a duration of 10 - 20 ps, thus reaching unprecedented dose rates in the range of $10^{10} - 10^{12}$ Gy/s.…
BACKGROUND: 155Tb represents a potentially useful radionuclide for diagnostic medical applications, but its production remains a challenging problem. A recent experimental campaign, conducted with low-energy proton beams impinging on a…
Objectives: Distinguishing between radiation necrosis(RN) and metastatic progression is extremely challenging due to their similarity in conventional imaging. This is crucial from a therapeutic point of view as this determines the outcome…
Background: With the advent of Intensity Modulated Radiotherapy (IMRT) and recently, Volumetric Modulated Arc Therapy (VMAT), treatment planning using Flattening Filter Free (FFF) beams can meet all of the energy requirements in radiation…
Modern electron tomography has progressed to higher resolution at lower doses by leveraging compressed sensing methods that minimize total variation (TV). However, these sparsity-emphasized reconstruction algorithms introduce tunable…
Flexible needle insertion procedures are common for minimally-invasive surgeries for diagnosing and treating prostate cancer. Bevel-tip needles provide physicians the capability to steer the needle during long insertions to avoid vital…
Fast phase-contrast imaging offered by modern synchrotron facilities opens the possibility of imaging dynamic processes of biological material such as cells. Cells are mainly composed of carbon and hydrogen, which have low X-ray…
We recently proposed a new approach for the real-time monitoring of particle therapy treatments with the goal of achieving high sensitivities on the particle range measurement already at limited counting statistics. This method extends the…
High-power microwave applications are growing for both military and civil purposes, yet they can induce brain-related risks and raise important public health concerns. High-power sub-millisecond radio frequency energy pulses have been…
Skeletal muscle modeling has a vital role in movement studies and the development of therapeutic approaches. In the current study, a Huxley-based model for skeletal muscle is proposed, which demonstrates the impact of impairments in muscle…
In order to study the local interactions between facial soft-tissues and a Silhouette Soft suspension suture, a CE marked medical device designed for the repositioning of soft tissues in the face and the neck, Finite element simulations…
Photoacoustic imaging (PAI) is a novel modality in biomedical imaging technology that combines the rich optical contrast with the deep penetration of ultrasound. To date, PAI technology has found applications in various biomedical fields.…
The emergence of artificial general intelligence (AGI) is transforming radiation oncology. As prominent vanguards of AGI, large language models (LLMs) such as GPT-4 and PaLM 2 can process extensive texts and large vision models (LVMs) such…
In recent years, the steerable needles have attracted significant interest in Minimally Invasive Surgery (MIS). Amongst these, the flexible Programmable-bevel tip needle (PBN) concept has successfully achieved an in-vivo demonstration to…
Background: Whereas filtered back projection algorithms for voxel-based CT image reconstruction have noise properties defined by the filter, iterative algorithms must stop at some point in their convergence and do not necessarily produce…
3D ultrasound imaging provides more spatial information compared to conventional 2D frames by considering the volumes of data. One of the main bottlenecks of 3D imaging is the long data acquisition time which reduces practicality and can…
Biodegradable and biocompatible 3D printable biomaterials with tunable mechanical properties and degradation rate adapted to target tissues were urgently required to manufacture scaffolds for tissue regeneration. Herein, a strategy based on…
The finite element method (FEM) is commonly used in computational cardiac simulations. For this method, a mesh is constructed to represent the geometry and, subsequently, to approximate the solution. To accurately capture curved geometrical…
Surgical masks have played a crucial role in healthcare facilities to protect against respiratory and infectious diseases, particularly during the COVID-19 pandemic. However, the synthetic fibers, mainly made of polypropylene, used in their…
Several clinical methods had been utilized for diagnosis of COVID-19 for instance, real-time reverse transcription-polymerase chain reaction (rRT-PCR), hematology examination, polymerase chain reaction (PCR), diagnostic guidelines based on…