生物物理
Fusion of two epithelial cell sheets brought together in a bilayer configuration is a common step in animal morphogenesis, yet, in contrast to other epithelial fusion processes such as wound healing in a monolayer of cells, it has not been…
What is life? In this work, we take life to mean a dynamical tendency to conserve identity for as long as possible. For a single bacterium, identity is carried by its chromosomal DNA code, so the bacterium is alive precisely insofar as it…
We present a unified physical theory demonstrating that human subjective time perception does not track geometric coordinate time $t$, but instead emerges from a local metric mutation driven by macroscopic physical entropy production. By…
Active fluids consisting of living cells or synthetic microswimmers display rich emergent behavior and nonequilibrium mechanical properties, which not only shed light on various biological processes but also inform the engineering of…
In previous work it was argued that the cells of a multicellular organism form a classically coherent system and that such coherence is essential for life. Here we make this claim precise by introducing an explicit classical formalism in…
The rapid growth of energy-intensive technologies, including artificial intelligence, large-scale computing, and thermal management systems, has intensified global energy demand amid accelerating climate change. Meeting these demands…
Signal recognition plays a critical role in species interactions and can be enhanced by learning signal characteristics through experience. In brood parasitism, host species may use visual cues to recognize and reject parasite eggs from…
Microbes in marine environments are often confined to thin near-surface layers while being advected by turbulent flows. Because such constrained advection generates an effectively compressible flow, reproduction and transport interact in a…
Plankton fix about 40 gigatons of carbon annually, using photosynthesis to convert $\text{CO}_2$ into $\text{O}_2$ and carbohydrates. These solutes are exchanged with the ocean in a diffusive boundary layer around the organism called the…
Self-organization is a defining feature of living systems, with order often maintained through interactions between constituent units rather than centralized feedback. We introduce a tractable mean-field model of self-organized robustness,…
In a low Reynolds number fluid environment that microswimmers encounter, back-and-forth motion cannot lead to net displacement. In mammalian sperm, the mechanical wave propagating along their single flagellum breaks the cancellation between…
Virological measurements are often treated as reports of virion structure, mechanics, dielectric response, infectivity, or titer. In practice, an experiment observes a protocol-conditioned projection of a richer latent virion--environment…
Why does the mammalian vascular tree maintain a conserved branching exponent $\alpha^* \approx 2.72$ across a $10^7$-fold range in body mass, despite a fundamental shift from viscous to wave-dominated transport? We prove this universality…
Murray's cubic branching law ($\alpha=3$) predicts a universal diameter scaling exponent for all hierarchical transport networks, yet arterial trees yield $\alpha \sim 2.7-2.9$. We show that this discrepancy has a structural origin:…
Biofilms in porous media critically influence hydraulic properties in environmental and engineered systems. However, a mechanistic understanding of how microbial life controls permeability remains elusive. By combining microfluidics,…
The pursuit-evasion game is studied for two adversarial active agents, modelled as a deterministic self-steering pursuer and a stochastic, cognitive evader. The pursuer chases the evader by reorienting its propulsion direction with limited…
Living cells are energy- and information-processing systems that sustain a nonequilibrium steady state (NESS) by continuously consuming energy and dissipating heat, as required by the second law of thermodynamics. The rate of heat…
Primary hemostasis is initiated by platelet adhesion and aggregation at a site of vascular injury and is strongly regulated by local hydrodynamic conditions. At elevated shear rates, platelet capture is mediated by von Willebrand factor…
Body-mass growth is usually described by continuous models that represent the gradual increase of mass toward an adult or asymptotic value. In this work, we formulate and test an alternative description based on a Fibonacci-inspired…
Ultraweak photon emission, also referred to as biological autoluminescence or biophoton emission, is the spontaneous emission of extremely low levels of light from a broad range of biological systems. Recent studies have reported that UPE…