生物物理
In the course of various biological processes, specific DNA-binding proteins must find a particular target sequence/protein or a damaged site on the DNA efficiently. DNA-binding proteins perform this task based on diffusion. Yet,…
Spatial Frequency Domain Imaging can map tissue scattering and absorption properties over a wide field of view, making it useful for clinical applications such as wound assessment and surgical guidance. This technique has previously…
Ion beam therapy is one of the most progressive methods in cancer treatment. Studies of the water radiolysis process show that the most long-living species that occur in the medium of a biological cell under the action of ionizing…
We introduce a novel generalization of the discrete nonlinear Schr\"odinger equation. It supports solitons that describe how proteins fold. As an example we scrutinize the villin headpiece HP35, an archetypal protein for testing both…
Collective cell motility is crucial to many biological processes including morphogenesis, wound healing, and cancer invasion. Recently, the biology and biophysics communities have begun to use the term cell jamming to describe the…
Receptor-ligand interactions are essential for biological function and their binding strength is commonly explained in terms of static lock-and-key models based on molecular complementarity. However, detailed information of the full…
A mathematical model is proposed for shape evolution and locomotion of fish epidermal keratocytes on elastic substrates. The model is based on mechanosensing concepts: cells apply contractile forces onto the elastic substrate, while cell…
Food production needs to increase significantly in 30 years, and water loss from plants may hold one key, especially relevant in a time of climate change. The plant leaf cuticle is the final defence of leaves in drought and at night, and so…
We propose a model for demixing of two species by assuming a density-dependent effective diffusion coefficient of the particles. Both sorts of microswimmers diffuse as active overdamped Brownian particles with a noise intensity that is…
Accurate assessment of stiffness distribution is essential due to the critical role of single cell mechanobiology in the regulation of many vital cellular processes such as proliferation, adhesion, migration, and motility. Cell stiffness is…
Protein function may be modulated by an event occurring far away from the functional site, a phenomenon termed allostery. While classically allostery involves conformational changes, we recently observed that charge redistribution within an…
The outbreak of the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has become a worldwide public health crisis. When the SARS-CoV-2 enters the biological fluids in the human body,…
The mechanism of negative group delay (NGD) is used to understand the anticipatory capability of a retina. Experiments with retinas from bull frogs are performed to compare with the predictions of the NGD model. In particulars, whole field…
Neural avalanches are collective firings of neurons that exhibit emergent scale-free behavior. Understanding the nature and distribution of these avalanches is an important element in understanding how the brain functions. We study a model…
We present a simple kinetic model for the assembly of small single-stranded RNA viruses that can be used to carry out analytical packaging contests between different types of RNA molecules. The RNA selection mechanism is purely kinetic and…
Super-resolutive 3D tracking, such as PSF engineering or evanescent field imaging has long been used to track microparticles and to enhance the throughput of single molecules force spectroscopic measurements. However, current methods…
Mechanical algesia is an important process for the preservation of living organisms, allowing potentially life-saving reflexes or decisions when given body parts are stressed. Yet, its various underlying mechanisms remain to be fully…
Droplet interface bilayers are a convenient model system to study the physio-chemical properties of phospholipid bilayers, the major component of the cell membrane. The mechanical response of these bilayers to various external mechanical…
The biosorption of Cr(VI)_ and Cr(III)_ of Arthrobacter species (Arthrobacter globiformis and Arthrobacter oxidas) was studied application dialysis and atomic absorption analysis at various Na(I) concentrations. Is was shown significant…
Combined effects of 137Cs gamma irradiation and heavy metal ions Ni(II), Zn(II), Ag(I) on Spirulina platensis cells using UV-VIS spectrometry after three times irradiation and recultivation were discussed. It was shown, that possible use of…