Green fluorescent proteins as optically-controllable elements in bioelectronics
凝聚态物理
2009-11-07 v1 q-bio
摘要
A single-biomolecule optical toggle-switch is demonstrated based on a mutated green fluorescent protein (GFP). We have exploited molecular biology techniques to tailor GFP molecular structure and photophysical properties and give it optically-controlled bistability between two distinct states. We present optical control of the fluorescence dynamics with two laser beams at 476 and 350 nm down to the ultimate limit of single molecules. These results indicate that GFP-class fluorophores are promising candidates for the realization of biomolecular devices such as volumetric optical memories and optical switches.
引用
@article{arxiv.cond-mat/0107576,
title = {Green fluorescent proteins as optically-controllable elements in bioelectronics},
author = {Riccardo A. G. Cinelli and Vittorio Pellegrini and Aldo Ferrari and Paolo Faraci and Riccardo Nifosi' and Mudit Tyagi and Mauro Giacca and Fabio Beltram},
journal= {arXiv preprint arXiv:cond-mat/0107576},
year = {2009}
}
备注
8 pages, 3 figures