用于靶向免疫检查点受体的 AGuIX 纳米颗粒-纳米抗体生物偶联物
生物物理
2024-01-05 v1
摘要
比较了点击化学和分选酶标记接枝策略，以利用纳米抗体功能化 AGuIX 纳米颗粒，从而开发一种结合 MRI 成像、放射治疗和免疫治疗（通过抑制免疫检查点）的三功能技术。
引用
@article{arxiv.2401.02149,
title = {AGuIX nanoparticle-nanobody bioconjugates to target immune checkpoint receptors},
author = {Léna Carmès and Guillaume Bort and François Lux and Léa Seban and Paul Rocchi and Zeinaf Muradova and Agnès Hagège and Laurence Heinrich-Balard and Frédéric Delolme and Virginie Gueguen-Chaignon and Charles Truillet and Stephanie Crowley and Elisa Bello and Tristan Doussineau and Michael Dougan and Olivier Tillement and Jonathan Schoenfeld and Needa Brown and Ross Berbeco},
journal= {arXiv preprint arXiv:2401.02149},
year = {2024}
}
备注
Nanoscale, 2024