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Data privacy is a critical challenge in modern medical workflows as the adoption of electronic patient records has grown rapidly. Stringent data protection regulations limit access to clinical records for training and integrating machine…

Counterfactual explanations aim to enhance model transparency by showing how inputs can be minimally altered to change predictions. For multivariate time series, existing methods often generate counterfactuals that are invalid, implausible,…

Machine Learning · Computer Science 2026-02-18 Sarah Seifi , Anass Ibrahimi , Tobias Sukianto , Cecilia Carbonelli , Lorenzo Servadei , Robert Wille

Cardiac rehabilitation constitutes a structured clinical process involving multiple interdependent phases, individualized medical decisions, and the coordinated participation of diverse healthcare professionals. This sequential and adaptive…

Machine Learning · Computer Science 2025-12-25 Alexandre Cabodevila , Pedro Gamallo-Fernandez , Juan C. Vidal , Manuel Lama

False medical information on social media poses harm to people's health. While the need for biomedical fact-checking has been recognized in recent years, user-generated medical content has received comparably little attention. At the same…

Computation and Language · Computer Science 2022-09-19 Amelie Wührl , Roman Klinger

We propose an architecture for training generative models of counterfactual conditionals of the form, 'can we modify event A to cause B instead of C?', motivated by applications in robot control. Using an 'adversarial training' paradigm, an…

Robotics · Computer Science 2020-09-23 Simón C. Smith , Subramanian Ramamoorthy

Sequential Recommender Systems (SRSs) have demonstrated remarkable effectiveness in capturing users' evolving preferences. However, their inherent complexity as "black box" models poses significant challenges for explainability. This work…

Information Retrieval · Computer Science 2025-08-06 Domiziano Scarcelli , Filippo Betello , Giuseppe Perelli , Fabrizio Silvestri , Gabriele Tolomei

This study investigates a data-driven machine learning approach to predict membrane fouling in critically ill patients undergoing Continuous Renal Replacement Therapy (CRRT). Using time-series data from an ICU, 16 clinically selected…

The investment of time and resources for better strategies and methodologies to tackle a potential pandemic is key to deal with potential outbreaks of new variants or other viruses in the future. In this work, we recreated the scene of a…

Machine Learning · Computer Science 2021-04-22 Andrés L. Suárez-Cetrulo , Ankit Kumar , Luis Miralles-Pechuán

Domain shift, encountered when using a trained model for a new patient population, creates significant challenges for sequential decision making in healthcare since the target domain may be both data-scarce and confounded. In this paper, we…

Machine Learning · Computer Science 2022-03-17 Taylor W. Killian , Marzyeh Ghassemi , Shalmali Joshi

To construct interpretable explanations that are consistent with the original ML model, counterfactual examples---showing how the model's output changes with small perturbations to the input---have been proposed. This paper extends the work…

Machine Learning · Computer Science 2020-06-16 Divyat Mahajan , Chenhao Tan , Amit Sharma

The availability of a large amount of electronic health records (EHR) provides huge opportunities to improve health care service by mining these data. One important application is clinical endpoint prediction, which aims to predict whether…

Artificial Intelligence · Computer Science 2018-11-20 Luchen Liu , Jianhao Shen , Ming Zhang , Zichang Wang , Jian Tang

Counterfactual thinking is a crucial yet challenging topic for artificial intelligence to learn knowledge from data and ultimately improve performance for new scenarios. Many research works, including the Potential Outcome Model (POM) and…

Artificial Intelligence · Computer Science 2026-02-24 Mingyu Kang , Duxin Chen , Ziyuan Pu , Jianxi Gao , Wenwu Yu

Video-language models (VLMs) achieve strong multimodal understanding but remain prone to hallucinations, especially when reasoning about actions and temporal order. Existing mitigation strategies, such as textual filtering or random video…

Computer Vision and Pattern Recognition · Computer Science 2026-01-09 Tobia Poppi , Burak Uzkent , Amanmeet Garg , Lucas Porto , Garin Kessler , Yezhou Yang , Marcella Cornia , Lorenzo Baraldi , Rita Cucchiara , Florian Schiffers

Medical time series are often irregular and face significant missingness, posing challenges for data analysis and clinical decision-making. Existing methods typically adopt a single modeling perspective, either treating series data as…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Liuqing Chen , Shuhong Xiao , Shixian Ding , Shanhai Hu , Lingyun Sun

Deep generative models have demonstrated remarkable success in medical image synthesis. However, ensuring conditioning faithfulness and high-quality synthetic images for direct or counterfactual generation remains a challenge. In this work,…

Computer Vision and Pattern Recognition · Computer Science 2025-10-31 Fangrui Huang , Alan Wang , Binxu Li , Bailey Trang , Ridvan Yesiloglu , Tianyu Hua , Wei Peng , Ehsan Adeli

Clinical risk prediction is a valuable tool for guiding healthcare interventions toward those most likely to benefit. Yet, evaluating the pairing of a risk prediction model with an intervention using randomized controlled trials presents…

Methodology · Statistics 2025-10-31 Valerie Odeh-Couvertier , Gabriel Zayas-Caban , Brian Patterson , Amy Cochran

Generating datasets that "look like" given real ones is an interesting tasks for healthcare applications of ML and many other fields of science and engineering. In this paper we propose a new method of general application to binary datasets…

Machine Learning · Statistics 2018-07-05 Laura Aviñó , Matteo Ruffini , Ricard Gavaldà

The COVID-19 pandemic has created unprecedented challenges worldwide. Strained healthcare providers make difficult decisions on patient triage, treatment and care management on a daily basis. Policy makers have imposed social distancing…

Deep learning (DL) models in medical imaging face challenges in generalizability and robustness due to variations in image acquisition parameters (IAP). In this work, we introduce a novel method using conditional denoising diffusion…

Image and Video Processing · Electrical Eng. & Systems 2024-11-01 Pedro Morão , Joao Santinha , Yasna Forghani , Nuno Loução , Pedro Gouveia , Mario A. T. Figueiredo

Machine learning models based on temporal point processes are the state of the art in a wide variety of applications involving discrete events in continuous time. However, these models lack the ability to answer counterfactual questions,…

Machine Learning · Computer Science 2022-05-23 Kimia Noorbakhsh , Manuel Gomez Rodriguez
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