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In recent years, various machine and deep learning architectures have been successfully introduced to the field of predictive process analytics. Nevertheless, the inherent opacity of these algorithms poses a significant challenge for human…

Artificial Intelligence · Computer Science 2024-03-15 Alexander Stevens , Chun Ouyang , Johannes De Smedt , Catarina Moreira

The prevalence of machine learning models in various industries has led to growing demands for model interpretability and for the ability to provide meaningful recourse to users. For example, patients hoping to improve their diagnoses or…

Machine Learning · Computer Science 2021-05-28 Daniel Nemirovsky , Nicolas Thiebaut , Ye Xu , Abhishek Gupta

Conversational recommender systems (CRSs) aim to provide recommendation services via natural language conversations. Although a number of approaches have been proposed for developing capable CRSs, they typically rely on sufficient training…

Computation and Language · Computer Science 2024-06-21 Xiaolei Wang , Kun Zhou , Xinyu Tang , Wayne Xin Zhao , Fan Pan , Zhao Cao , Ji-Rong Wen

While state-of-the-art NLP models have been achieving the excellent performance of a wide range of tasks in recent years, important questions are being raised about their robustness and their underlying sensitivity to systematic biases that…

Computation and Language · Computer Science 2022-03-25 Linyi Yang , Jiazheng Li , Pádraig Cunningham , Yue Zhang , Barry Smyth , Ruihai Dong

Synthetic time series are often used in practical applications to augment the historical time series dataset for better performance of machine learning algorithms, amplify the occurrence of rare events, and also create counterfactual…

Machine Learning · Computer Science 2023-09-18 Andrea Coletta , Sriram Gopalakrishan , Daniel Borrajo , Svitlana Vyetrenko

Machine learning models perform well on several healthcare tasks and can help reduce the burden on the healthcare system. However, the lack of explainability is a major roadblock to their adoption in hospitals. \textit{How can the decision…

Machine Learning · Computer Science 2023-06-13 Supriya Nagesh , Nina Mishra , Yonatan Naamad , James M. Rehg , Mehul A. Shah , Alexei Wagner

Machine Learning has seen tremendous growth recently, which has led to larger adoption of ML systems for educational assessments, credit risk, healthcare, employment, criminal justice, to name a few. The trustworthiness of ML and NLP…

Computation and Language · Computer Science 2021-03-19 Nishtha Madaan , Inkit Padhi , Naveen Panwar , Diptikalyan Saha

LLMs can be unpredictable, as even slight alterations to the prompt can cause the output to change in unexpected ways. Thus, the ability of models to accurately explain their behavior is critical, especially in high-stakes settings. One…

Computation and Language · Computer Science 2025-11-26 Marvin Limpijankit , Yanda Chen , Melanie Subbiah , Nicholas Deas , Kathleen McKeown

Counterfactual inference is a useful tool for comparing outcomes of interventions on complex systems. It requires us to represent the system in form of a structural causal model, complete with a causal diagram, probabilistic assumptions on…

Treatment effects can be estimated from observational data as the difference in potential outcomes. In this paper, we address the challenge of estimating the potential outcome when treatment-dose levels can vary continuously over time.…

Machine Learning · Statistics 2017-11-07 Hossein Soleimani , Adarsh Subbaswamy , Suchi Saria

Reconstructing precise clinical timelines is essential for modeling patient trajectories and forecasting risk in complex, heterogeneous conditions like sepsis. While unstructured clinical narratives offer semantically rich and contextually…

Computation and Language · Computer Science 2026-05-15 Sayantan Kumar , Shahriar Noroozizadeh , Juyong Kim , Jeremy C. Weiss

This paper tackles the problem of time-to-event counterfactual survival prediction, aiming to optimize individualized survival outcomes in the presence of heterogeneity and censored data. We propose CURE, a framework that advances…

Access to electronic health records (EHRs) for digital health research is often limited by privacy regulations and institutional barriers. Synthetic EHRs have been proposed as a way to enable safe and sovereign data sharing; however,…

Machine Learning · Computer Science 2026-03-10 Guanglin Zhou , Armin Catic , Motahare Shabestari , Matthew Young , Chaiquan Li , Katrina Poppe , Sebastiano Barbieri

This study presents a novel framework for counterfactual user behavior forecasting that combines structural causal models with transformer-based generative artificial intelligence. To model fictitious situations, the method creates causal…

Machine Learning · Computer Science 2025-11-12 Dharmateja Priyadarshi Uddandarao , Ravi Kiran Vadlamani

Evidence derived from large-scale real-world data (RWD) is increasingly informing regulatory evaluation and healthcare decision-making. Administrative claims provide population-scale, longitudinal records of healthcare utilization,…

During the COVID-19 pandemic, different countries, regions, and communities constructed various epidemic models to evaluate spreading behaviors and assist in making mitigation policies. Model uncertainties, introduced by complex…

Physics and Society · Physics 2025-06-23 Baike She , Rebecca Lee Smith , Ian Pytlarz , Shreyas Sundaram , Philip E. Paré

Estimating counterfactual outcomes over time from observational data is relevant for many applications (e.g., personalized medicine). Yet, state-of-the-art methods build upon simple long short-term memory (LSTM) networks, thus rendering…

Machine Learning · Computer Science 2022-06-06 Valentyn Melnychuk , Dennis Frauen , Stefan Feuerriegel

Counterfactual reasoning requires predicting how alternative events, contrary to what actually happened, might have resulted in different outcomes. Despite being considered a necessary component of AI-complete systems, few resources have…

Computation and Language · Computer Science 2019-09-13 Lianhui Qin , Antoine Bosselut , Ari Holtzman , Chandra Bhagavatula , Elizabeth Clark , Yejin Choi

Retrospective causal questions ask what would have happened to an observed individual had they received a different treatment. We study the problem of estimating $\mu(x,y)=\mathbb{E}[Y(1)\mid X=x,Y(0)=y]$, the expected counterfactual…

Methodology · Statistics 2026-03-31 Juraj Bodik

Balanced representation learning methods have been applied successfully to counterfactual inference from observational data. However, approaches that account for survival outcomes are relatively limited. Survival data are frequently…

Machine Learning · Statistics 2021-03-04 Paidamoyo Chapfuwa , Serge Assaad , Shuxi Zeng , Michael J. Pencina , Lawrence Carin , Ricardo Henao