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Estimating causal effects on time-to-event outcomes from observational data is particularly challenging due to censoring, limited sample sizes, and non-random treatment assignment. The need for answering such "when-if" questions--how the…

Machine Learning · Computer Science 2025-11-19 Jessy Xinyi Han , Devavrat Shah

Reinforcement learning (RL) algorithms usually require a substantial amount of interaction data and perform well only for specific tasks in a fixed environment. In some scenarios such as healthcare, however, usually only few records are…

Machine Learning · Computer Science 2020-12-17 Chaochao Lu , Biwei Huang , Ke Wang , José Miguel Hernández-Lobato , Kun Zhang , Bernhard Schölkopf

With the ongoing rise of machine learning, the need for methods for explaining decisions made by artificial intelligence systems is becoming a more and more important topic. Especially for image classification tasks, many state-of-the-art…

Machine Learning · Computer Science 2022-05-10 Silvan Mertes , Tobias Huber , Katharina Weitz , Alexander Heimerl , Elisabeth André

The increasing demand for mental health services has outpaced the availability of real training data to develop clinical professionals, leading to limited support for the diagnosis of depression. This shortage has motivated the development…

Computation and Language · Computer Science 2025-08-07 Xi Wang , Anxo Perez , Javier Parapar , Fabio Crestani

Recent text generation models are easy to generate relevant and fluent text for the given text, while lack of causal reasoning ability when we change some parts of the given text. Counterfactual story rewriting is a recently proposed task…

Computation and Language · Computer Science 2021-04-05 Changying Hao , Liang Pang , Yanyan Lan , Yan Wang , Jiafeng Guo , Xueqi Cheng

Healthcare requires AI that is predictive, reliable, and data-efficient. However, recent generative models lack physical foundation and temporal reasoning required for clinical decision support. As scaling language models show diminishing…

Machine Learning · Computer Science 2025-11-21 Mohammad Areeb Qazi , Maryam Nadeem , Mohammad Yaqub

In realistic scenarios, multivariate timeseries evolve over case-by-case time-scales. This is particularly clear in medicine, where the rate of clinical events varies by ward, patient, and application. Increasingly complex models have been…

Machine Learning · Computer Science 2020-03-06 Jacob Deasy , Ari Ercole , Pietro Liò

Deep NLP models have been shown to learn spurious correlations, leaving them brittle to input perturbations. Recent work has shown that counterfactual or contrastive data -- i.e. minimally perturbed inputs -- can reveal these weaknesses,…

Computation and Language · Computer Science 2022-03-31 Bhargavi Paranjape , Matthew Lamm , Ian Tenney

Counterfactual explanations are increasingly proposed as interpretable mechanisms to achieve algorithmic recourse. However, current counterfactual techniques for time series classification are predominantly designed with static data…

Machine Learning · Computer Science 2025-12-17 Emmanuel C. Chukwu , Rianne M. Schouten , Monique Tabak , Mykola Pechenizkiy

Conditional generation models for longitudinal sequences can produce new or modified trajectories given a conditioning input. However, they often lack control over when the condition should take effect (timing) and which variables it should…

Machine Learning · Computer Science 2026-03-10 Michelle M. Li , Kevin Li , Yasha Ektefaie , Ying Jin , Yepeng Huang , Shvat Messica , Tianxi Cai , Marinka Zitnik

Deep learning models in medical imaging often fail when deployed in new clinical environments due to distribution shifts in demographics, scanner hardware, or acquisition protocols. A central challenge is underspecification, where models…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Moritz Stammel , Fabio De Sousa Ribeiro , Raghav Mehta , Mélanie Roschewitz , Ben Glocker

Patient simulation is essential for developing and evaluating mental health dialogue systems. As most existing approaches rely on snapshot-style prompts with limited profile information, homogeneous behaviors and incoherent disease…

Computation and Language · Computer Science 2026-03-25 Baihan Li , Bingrui Jin , Kunyao Lan , Ming Wang , Mengyue Wu

We present a novel generative method for producing unseen and plausible counterfactual examples for reinforcement learning (RL) agents based upon outcome variables that characterize agent behavior. Our approach uses a variational…

Artificial Intelligence · Computer Science 2022-07-19 Eric Yeh , Pedro Sequeira , Jesse Hostetler , Melinda Gervasio

Accurate and comprehensive clinical documentation is crucial for delivering high-quality healthcare, facilitating effective communication among providers, and ensuring compliance with regulatory requirements. However, manual transcription…

Computation and Language · Computer Science 2024-06-12 Anjanava Biswas , Wrick Talukdar

In real-world machine learning systems, labels are often derived from user behaviors that the system wishes to encourage. Over time, new models must be trained as new training examples and features become available. However, feedback loops…

Machine Learning · Computer Science 2023-11-01 Victoria Lin , Louis-Philippe Morency , Dimitrios Dimitriadis , Srinagesh Sharma

To draw real-world evidence about the comparative effectiveness of multiple time-varying treatments on patient survival, we develop a joint marginal structural survival model and a novel weighting strategy to account for time-varying…

Methodology · Statistics 2023-08-08 Liangyuan Hu , Jiayi Ji , Himanshu Joshi , Erick Scott , Fan Li

Being able to reason about how one's behaviour can affect the behaviour of others is a core skill required of intelligent driving agents. Despite this, the state of the art struggles to meet the need of agents to discover causal links…

Robotics · Computer Science 2024-03-07 Rhys Howard , Lars Kunze

In personalized medicine, the ability to predict and optimize treatment outcomes across various time frames is essential. Additionally, the ability to select cost-effective treatments within specific budget constraints is critical. Despite…

Machine Learning · Computer Science 2024-10-14 Thomas Schwarz , Cecilia Casolo , Niki Kilbertus

The unprecedented global crisis brought about by the COVID-19 pandemic has sparked numerous efforts to create predictive models for the detection and prognostication of SARS-CoV-2 infections with the goal of helping health systems allocate…

We present a human-in-the-loop approach to generate counterfactual (CF) explanations that preserve global and local feasibility constraints. Global feasibility constraints refer to the causal constraints that are necessary for generating…

Machine Learning · Computer Science 2022-10-13 Homayun Afrabandpey , Michael Spranger