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We propose MatSci ML, a novel benchmark for modeling MATerials SCIence using Machine Learning (MatSci ML) methods focused on solid-state materials with periodic crystal structures. Applying machine learning methods to solid-state materials…

Spatiotemporal reasoning plays a key role in Cyber-Physical Systems (CPS). Despite advances in Large Language Models (LLMs) and Large Reasoning Models (LRMs), their capacity to reason about complex spatiotemporal signals remains…

Artificial Intelligence · Computer Science 2026-01-13 Pengrui Quan , Brian Wang , Kang Yang , Liying Han , Mani Srivastava

State Space Models (SSMs) have emerged as a potent tool in sequence modeling tasks in recent years. These models approximate continuous systems using a set of basis functions and discretize them to handle input data, making them well-suited…

Machine Learning · Computer Science 2024-07-16 Jiaxi Hu , Disen Lan , Ziyu Zhou , Qingsong Wen , Yuxuan Liang

Modeling long-range dependencies in sequential data remains a central challenge in machine learning. Transformers address this challenge through attention mechanisms, but their quadratic complexity with respect to sequence length limits…

Machine Learning · Computer Science 2026-05-14 Hoang-Quan Nguyen , Sankalp Pandey , Khoa Luu

This chapter provides a brief introduction to the theory and practice of spatial stochastic simulations. It begins with an overview of different methods available for biochemical simulations highlighting their strengths and limitations.…

Quantitative Methods · Quantitative Biology 2018-10-02 Sanjana Gupta , Jacob Czech , Robert Kuczewski , Thomas M. Bartol , Terrence J. Sejnowski , Robin E. C. Lee , James R. Faeder

Despite significant recent progress of Multimodal Large Language Models (MLLMs), current MLLMs are challenged by "spatio-temporal" prompts, i.e., prompts that refer to 1) the entirety of an environment encoded in a point cloud that the MLLM…

Computer Vision and Pattern Recognition · Computer Science 2025-10-16 Haozhen Zheng , Beitong Tian , Mingyuan Wu , Zhenggang Tang , Klara Nahrstedt , Alex Schwing

Recently, recurrent models based on linear state space models (SSMs) have shown promising performance in language modeling (LM), competititve with transformers. However, there is little understanding of the in-principle abilities of such…

Computation and Language · Computer Science 2025-12-15 Yash Sarrof , Yana Veitsman , Michael Hahn

Mammalian cells have about 30,000-fold more protein molecules than mRNA molecules. This larger number of molecules and the associated larger dynamic range have major implications in the development of proteomics technologies. We examine…

Quantitative Methods · Quantitative Biology 2023-03-14 Michael J. MacCoss , Javier Alfaro , Meni Wanunu , Danielle A. Faivre , Nikolai Slavov

State Space Models (SSMs) are powerful tools for modeling sequential data in computer vision and time series analysis domains. However, traditional SSMs are limited by fixed, one-dimensional sequential processing, which restricts their…

Machine Learning · Computer Science 2025-04-08 Nikola Zubić , Davide Scaramuzza

Sequence models have demonstrated the ability to perform tasks like channel equalization and symbol detection by automatically adapting to current channel conditions. This is done without requiring any explicit optimization and by…

Signal Processing · Electrical Eng. & Systems 2024-11-01 Zihang Song , Matteo Zecchin , Bipin Rajendran , Osvaldo Simeone

Small Language Models (SLMs) offer computational efficiency and accessibility, yet a systematic evaluation of their performance and environmental impact remains lacking. We introduce SLM-Bench, the first benchmark specifically designed to…

Computation and Language · Computer Science 2025-09-05 Nghiem Thanh Pham , Tung Kieu , Duc-Manh Nguyen , Son Ha Xuan , Nghia Duong-Trung , Danh Le-Phuoc

Deep neural networks based on state space models (SSMs) are attracting significant attention in sequence modeling since their computational cost is much smaller than that of Transformers. While the capabilities of SSMs have been…

Machine Learning · Statistics 2025-03-06 Naoki Nishikawa , Taiji Suzuki

Structured State Space Models (SSMs) have emerged as alternatives to transformers. While SSMs are often regarded as effective in capturing long-sequence dependencies, we rigorously demonstrate that they are inherently limited by strong…

Machine Learning · Computer Science 2025-03-12 Peihao Wang , Ruisi Cai , Yuehao Wang , Jiajun Zhu , Pragya Srivastava , Zhangyang Wang , Pan Li

We consider the problem of high-dimensional filtering of state-space models (SSMs) at discrete times. This problem is particularly challenging as analytical solutions are typically not available and many numerical approximation methods can…

Computation · Statistics 2022-01-13 Hamza Ruzayqat , Aimad Er-Raiy , Alexandros Beskos , Dan Crisan , Ajay Jasra , Nikolas Kantas

Dense video captioning is a challenging video understanding task which aims to simultaneously segment the video into a sequence of meaningful consecutive events and to generate detailed captions to accurately describe each event. Existing…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 AJ Piergiovanni , Ganesh Satish Mallya , Dahun Kim , Anelia Angelova

State-space models (SSMs) are powerful probabilistic tools for modeling time-varying systems with latent dynamics. Inference in SSMs involves the estimation of latent states and parameters. In this work, we focus on parameter inference,…

Computation · Statistics 2026-05-22 Kostas Tsampourakis , Víctor Elvira

The application of the Multi-modal Large Language Models (MLLMs) in medical clinical scenarios remains underexplored. Previous benchmarks only focus on the capacity of the MLLMs in medical visual question-answering (VQA) or report…

Computation and Language · Computer Science 2024-08-19 Hongcheng Liu , Yusheng Liao , Siqv Ou , Yuhao Wang , Heyang Liu , Yanfeng Wang , Yu Wang

Emerging applications such as AR are driving demands for machine intelligence capable of processing continuous and/or long-context inputs on local devices. However, currently dominant models based on Transformer architecture suffers from…

Hardware Architecture · Computer Science 2026-03-24 Saptarshi Mitra , Rachid Karami , Haocheng Xu , Sitao Huang , Hyoukjun Kwon

State-space models (SSMs) have recently shown promise in capturing long-range dependencies with subquadratic computational complexity, making them attractive for various applications. However, purely SSM-based models face critical…

Computer Vision and Pattern Recognition · Computer Science 2025-04-01 Abdelrahman Shaker , Syed Talal Wasim , Salman Khan , Juergen Gall , Fahad Shahbaz Khan

Modern large language models are built on sequence modeling via next-token prediction. While the Transformer remains the dominant architecture for sequence modeling, its quadratic decoding complexity in sequence length poses a major…

Machine Learning · Computer Science 2024-10-03 Bo Liu , Rui Wang , Lemeng Wu , Yihao Feng , Peter Stone , Qiang Liu