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State space models (SSMs) have shown impressive results on tasks that require modeling long-range dependencies and efficiently scale to long sequences owing to their subquadratic runtime complexity. Originally designed for continuous…

Computation and Language · Computer Science 2023-10-31 Mahan Fathi , Jonathan Pilault , Orhan Firat , Christopher Pal , Pierre-Luc Bacon , Ross Goroshin

State space models (SSMs) have high performance on long sequence modeling but require sophisticated initialization techniques and specialized implementations for high quality and runtime performance. We study whether a simple alternative…

Machine Learning · Computer Science 2023-02-15 Daniel Y. Fu , Elliot L. Epstein , Eric Nguyen , Armin W. Thomas , Michael Zhang , Tri Dao , Atri Rudra , Christopher Ré

A proper parametrization of state transition matrices of linear state-space models (SSMs) followed by standard nonlinearities enables them to efficiently learn representations from sequential data, establishing the state-of-the-art on a…

Machine Learning · Computer Science 2022-09-28 Ramin Hasani , Mathias Lechner , Tsun-Hsuan Wang , Makram Chahine , Alexander Amini , Daniela Rus

State Space Models (SSMs) have emerged as a compelling alternative to attention models for long-range vision tasks, offering input-dependent recurrence with linear complexity. However, most efficient SSM variants reduce computation cost by…

Computer Vision and Pattern Recognition · Computer Science 2026-05-13 Sara Shoouri , Morteza Tavakoli Taba , Hun-Seok Kim

Spatial patterning is common in ecological systems and has been extensively studied via different modeling approaches. Individual-based models (IBMs) accurately describe nonlinear interactions at the organism level and the stochastic…

Populations and Evolution · Quantitative Biology 2025-04-16 Anudeep Surendran , David Pinto-Ramos , Rafael Menezes , Ricardo Martinez-Garcia

Security-constrained unit commitment (SCUC) is a computationally complex process utilized in power system day-ahead scheduling and market clearing. SCUC is run daily and requires state-of-the-art algorithms to speed up the process. The…

Machine Learning · Computer Science 2023-06-05 Arun Venkatesh Ramesh , Xingpeng Li

Accurate fMRI analysis requires sensitivity to temporal structure across multiple scales, as BOLD signals encode cognitive processes that emerge from fast transient dynamics to slower, large-scale fluctuations. Existing deep learning (DL)…

Signal Processing · Electrical Eng. & Systems 2026-01-06 Furkan Genç , Boran İsmet Macun , Sait Sarper Özaslan , Emine U. Saritas , Tolga Çukur

Markov population models (MPMs) are a widely used modelling formalism in the area of computational biology and related areas. The semantics of a MPM is an infinite-state continuous-time Markov chain. In this paper, we use the established…

Numerical Analysis · Computer Science 2014-06-10 David Spieler , Ernst Moritz Hahn , Lijun Zhang

Markov state models (MSMs) have been successful in computing metastable states, slow relaxation timescales and associated structural changes, and stationary or kinetic experimental observables of complex molecules from large amounts of…

Chemical Physics · Physics 2015-06-17 Frank Noe , Hao Wu , Jan-Hendrik Prinz , Nuria Plattner

Over the past few years, research on deep graph learning has shifted from static graphs to temporal graphs in response to real-world complex systems that exhibit dynamic behaviors. In practice, temporal graphs are formalized as an ordered…

Machine Learning · Computer Science 2024-10-30 Jintang Li , Ruofan Wu , Xinzhou Jin , Boqun Ma , Liang Chen , Zibin Zheng

State space models (SSMs) are a powerful and widely-used class of probabilistic models for analysing time-series data across various fields, from econometrics to robotics. Despite their prevalence, existing software frameworks for SSMs…

Computation · Statistics 2025-05-30 Tim Hargreaves , Qing Li , Charles Knipp , Frederic Wantiez , Simon J. Godsill , Hong Ge

Recently, multimodal large language models (MLLMs) have achieved significant advancements across various domains, and corresponding evaluation benchmarks have been continuously refined and improved. In this process, benchmarks in the…

Computation and Language · Computer Science 2025-08-20 Jiacheng Ruan , Dan Jiang , Xian Gao , Ting Liu , Yuzhuo Fu , Yangyang Kang

Existing models encounter bottlenecks in balancing performance and computational efficiency when modeling long sequences. Although the state space model (SSM) has achieved remarkable success in handling long sequence tasks, it still faces…

Machine Learning · Computer Science 2025-05-06 Tongyi Liang , Han-Xiong Li

Tracking single molecules is instrumental for quantifying the transport of molecules and nanoparticles in biological samples, e.g., in brain drug delivery studies. Existing intensity-based localisation methods are not developed for imaging…

Humans excel at performing complex tasks by leveraging long-term memory across temporal and spatial experiences. In contrast, current Large Language Models (LLMs) struggle to effectively plan and act in dynamic, multi-room 3D environments.…

Computer Vision and Pattern Recognition · Computer Science 2025-12-18 Wenbo Hu , Yining Hong , Yanjun Wang , Leison Gao , Zibu Wei , Xingcheng Yao , Nanyun Peng , Yonatan Bitton , Idan Szpektor , Kai-Wei Chang

Large language models (LLMs) have recently demonstrated state-of-the-art performance across various natural language processing (NLP) tasks, achieving near-human levels in multiple language understanding challenges and aligning closely with…

Signal Processing · Electrical Eng. & Systems 2025-07-08 Zhenyi Wang , Li Zou , Shengyun Wei , Kai Li , Feifan Liao , Haibo Mi , Rongxuan Lai

Large language model (LLM) simulations of human behavior have the potential to revolutionize the social and behavioral sciences, if and only if they faithfully reflect real human behaviors. Current evaluations of simulation fidelity are…

Computation and Language · Computer Science 2026-04-14 Tiancheng Hu , Joachim Baumann , Lorenzo Lupo , Nigel Collier , Dirk Hovy , Paul Röttger

Sequence modeling plays a vital role across various domains, with recurrent neural networks being historically the predominant method of performing these tasks. However, the emergence of transformers has altered this paradigm due to their…

Multi-contrast Magnetic Resonance Imaging super-resolution (MC-MRI SR) aims to enhance low-resolution (LR) contrasts leveraging high-resolution (HR) references, shortening acquisition time and improving imaging efficiency while preserving…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Xiaoman Wu , Lubin Gan , Siying Wu , Jing Zhang , Yunwei Ou , Xiaoyan Sun

LLM agents have incredible potential for scientific discovery applications. However, the performance of LLM agents on real-world, small molecule drug design (SMDD) tasks across diverse chemistries and targets is unclear. Current evaluation…

Artificial Intelligence · Computer Science 2026-05-26 Kevin Han , Renfei Zhang , Kathy Wei , Hamed Mahdavi , Niloofar Mireshghallah , Amir Barati Farimani
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