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State Space Models (SSMs), developed to tackle long sequence modeling tasks efficiently, offer both parallelizable training and fast inference. At their core are recurrent dynamical systems that maintain a hidden state, with update costs…

Machine Learning · Computer Science 2026-02-26 Makram Chahine , Philipp Nazari , Daniela Rus , T. Konstantin Rusch

Large Vision-Language Models (LVLMs) have demonstrated remarkable performance across a wide range of multimodal tasks. However, fine-tuning these models for domain-specific applications remains a computationally intensive challenge. This…

Computer Vision and Pattern Recognition · Computer Science 2024-12-16 Chee Ng , Yuen Fung

State-space models (SSMs) are a class of networks for sequence learning that benefit from fixed state size and linear complexity with respect to sequence length, contrasting the quadratic scaling of typical attention mechanisms. Inspired…

Machine Learning · Computer Science 2025-10-02 Jared Boyer , T. Konstantin Rusch , Daniela Rus

State space models (SSM) have been widely applied for the analysis and visualization of large sequential datasets. Sequential Monte Carlo (SMC) is a very popular particle-based method to sample latent states from intractable posteriors.…

Machine Learning · Computer Science 2019-01-07 Duo Xu

This paper studies sequence modeling for prediction tasks with long range dependencies. We propose a new formulation for state space models (SSMs) based on learning linear dynamical systems with the spectral filtering algorithm (Hazan et…

Machine Learning · Computer Science 2024-07-12 Naman Agarwal , Daniel Suo , Xinyi Chen , Elad Hazan

Development and homeostasis in multicellular systems both require exquisite control over spatial molecular pattern formation and maintenance. Advances in spatially-resolved and high-throughput molecular imaging methods such as multiplexed…

Quantitative Methods · Quantitative Biology 2023-03-30 Alex J. Lee , Robert Cahill , Reza Abbasi-Asl

State-space models have been used in many applications, including econometrics, engineering, medical research, etc. The maximum likelihood estimation (MLE) of the static parameter of general state-space models is not straightforward because…

Methodology · Statistics 2025-02-04 Yuxiong Gao , Wentao Li , Rong Chen

Multimodal large language models (MLLMs) achieve strong performance by jointly processing inputs from multiple modalities, such as vision, audio, and language. However, building such models or extending them to new modalities often requires…

Machine Learning · Computer Science 2026-03-24 Md Kaykobad Reza , Ameya Patil , Edward Ayrapetian , M. Salman Asif

State-space models (SSM) with Markov switching offer a powerful framework for detecting multiple regimes in time series, analyzing mutual dependence and dynamics within regimes, and asserting transitions between regimes. These models…

Methodology · Statistics 2021-06-14 David Degras , Chee-Ming Ting , Hernando Ombao

State space models (SSMs) have emerged as a powerful framework for modelling long-range dependencies in sequence data. Unlike traditional recurrent neural networks (RNNs) and convolutional neural networks (CNNs), SSMs offer a structured and…

Machine Learning · Computer Science 2024-10-07 Siddhanth Bhat

Multimodal large language models (MLLMs) have advanced static visual--spatial reasoning, yet they often fail to preserve long-horizon spatial coherence in embodied settings where beliefs must be continuously revised from egocentric…

Computer Vision and Pattern Recognition · Computer Science 2026-05-29 Chih-Ting Liao , Xi Xiao , Chunlei Meng , Zhangquan Chen , Yitong Qiao , Weilin Zhou , Tianyang Wang , Xu Zheng , Xin Cao

Identifying wireless modulation schemes is essential for cognitive radio, but standard supervised models often degrade under distribution shift, and training domain-specific wireless foundation models from scratch is computationally…

Machine Learning · Computer Science 2026-03-30 Mohammad Rostami , Atik Faysal , Reihaneh Gh. Roshan , Huaxia Wang , Nikhil Muralidhar , Yu-Dong Yao

Molecular Dynamics (MD) is a powerful computational microscope for probing protein functions. However, the need for fine-grained integration and the long timescales of biomolecular events make MD computationally expensive. To address this,…

Machine Learning · Computer Science 2026-03-30 Kacper Kapuśniak , Cristian Gabellini , Michael Bronstein , Prudencio Tossou , Francesco Di Giovanni

Transformers have revolutionized image modeling tasks with adaptations like DeIT, Swin, SVT, Biformer, STVit, and FDVIT. However, these models often face challenges with inductive bias and high quadratic complexity, making them less…

Computer Vision and Pattern Recognition · Computer Science 2024-06-05 Badri N. Patro , Suhas Ranganath , Vinay P. Namboodiri , Vijay S. Agneeswaran

Despite the recent success of deep learning in continuous sign language recognition (CSLR), deep models typically focus on the most discriminative features, ignoring other potentially non-trivial and informative contents. Such…

Computer Vision and Pattern Recognition · Computer Science 2020-02-11 Hao Zhou , Wengang Zhou , Yun Zhou , Houqiang Li

Time series modeling is a well-established problem, which often requires that methods (1) expressively represent complicated dependencies, (2) forecast long horizons, and (3) efficiently train over long sequences. State-space models (SSMs)…

Machine Learning · Computer Science 2023-03-17 Michael Zhang , Khaled K. Saab , Michael Poli , Tri Dao , Karan Goel , Christopher Ré

Spiking neural networks (SNNs) take inspiration from the brain to enable energy-efficient computations. Since the advent of Transformers, SNNs have struggled to compete with artificial networks on modern sequential tasks, as they inherit…

Neural and Evolutionary Computing · Computer Science 2024-01-03 Matei Ioan Stan , Oliver Rhodes

The rapid advancement of large language models (LLMs) has led to significant improvements in natural language processing but also poses challenges due to their high computational and energy demands. This paper introduces a series of…

Computation and Language · Computer Science 2024-06-27 Dylan Hillier , Leon Guertler , Cheston Tan , Palaash Agrawal , Chen Ruirui , Bobby Cheng

Influenced by breakthroughs in LLMs, single-cell foundation models are emerging. While these models show successful performance in cell type clustering, phenotype classification, and gene perturbation response prediction, it remains to be…

We introduce a comprehensive framework for modeling single cell transcriptomic responses to perturbations, aimed at standardizing benchmarking in this rapidly evolving field. Our approach includes a modular and user-friendly model…