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Neural ranking models have become increasingly popular for real-world search and recommendation systems in recent years. Unlike their tree-based counterparts, neural models are much less interpretable. That is, it is very difficult to…

Information Retrieval · Computer Science 2024-05-14 Lijun Lyu , Nirmal Roy , Harrie Oosterhuis , Avishek Anand

In this paper, we introduce the Interpretable Cross-Examination Technique (ICE-T), a novel approach that leverages structured multi-prompt techniques with Large Language Models (LLMs) to improve classification performance over zero-shot and…

Computation and Language · Computer Science 2024-05-14 Goran Muric , Ben Delay , Steven Minton

Randomized trials typically estimate average relative treatment effects, but decisions on the benefit of a treatment are possibly better informed by more individualized predictions of the absolute treatment effect. In case of a binary…

Methodology · Statistics 2021-08-20 J Hoogland , J IntHout , M Belias , MM Rovers , RD Riley , FE Harrell , KGM Moons , TPA Debray , JB Reitsma

Black-box AI induction methods such as deep reinforcement learning (DRL) are increasingly being used to find optimal policies for a given control task. Although policies represented using a black-box AI are capable of efficiently executing…

Machine Learning · Computer Science 2023-03-16 Yashesh Dhebar , Kalyanmoy Deb , Subramanya Nageshrao , Ling Zhu , Dimitar Filev

The pursuit of decision safety in clinical applications highlights the potential of concept-based methods in medical imaging. While these models offer active interpretability, they often suffer from concept leakages, where unintended…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Yibo Gao , Hangqi Zhou , Zheyao Gao , Bomin Wang , Shangqi Gao , Sihan Wang , Xiahai Zhuang

The healthcare sector has experienced a rapid accumulation of digital data recently, especially in the form of electronic health records (EHRs). EHRs constitute a precious resource that IS researchers could utilize for clinical applications…

Machine Learning · Computer Science 2024-11-06 Thiti Suttaket , L Vivek Harsha Vardhan , Stanley Kok

Item Response Theory (IRT) is a ubiquitous model for understanding humans based on their responses to questions, used in fields as diverse as education, medicine and psychology. Large modern datasets offer opportunities to capture more…

Machine Learning · Computer Science 2020-03-17 Mike Wu , Richard L. Davis , Benjamin W. Domingue , Chris Piech , Noah Goodman

In Explainable AI, rule extraction translates model knowledge into logical rules, such as IF-THEN statements, crucial for understanding patterns learned by black-box models. This could significantly aid in fields like disease diagnosis,…

Machine Learning · Computer Science 2024-08-16 Yu Chen , Tianyu Cui , Alexander Capstick , Nan Fletcher-Loyd , Payam Barnaghi

Rule-based models, e.g., decision trees, are widely used in scenarios demanding high model interpretability for their transparent inner structures and good model expressivity. However, rule-based models are hard to optimize, especially on…

Machine Learning · Computer Science 2021-10-01 Zhuo Wang , Wei Zhang , Ning Liu , Jianyong Wang

There has been growing interest in developing optimal individualized treatment rules (ITRs) in various fields, such as precision medicine, business decision-making, and social welfare distribution. The application of ITRs within a societal…

Methodology · Statistics 2025-04-29 Wenhai Cui , Wen Su , Xiaodong Yan , Donglin Zeng , Xingqiu Zhao

Interpreting complex machine learning models is a critical challenge, especially for tabular data where model transparency is paramount. Local Interpretable Model-Agnostic Explanations (LIME) has been a very popular framework for…

Machine Learning · Computer Science 2026-03-24 Mohamed Aymen Bouyahia , Argyris Kalogeratos

Personalized decision-making, tailored to individual characteristics, is gaining significant attention. The optimal treatment regime aims to provide the best-expected outcome in the entire population, known as the value function. One…

Methodology · Statistics 2024-05-28 Yuwen Cheng , Shu Yang

This paper discusses identification, estimation, and inference on dynamic local average treatment effects (LATEs) in instrumental variables (IVs) settings. First, we show that compliers--observations whose treatment status is affected by…

Econometrics · Economics 2025-09-17 Alessandro Casini , Adam McCloskey , Luca Rolla , Raimondo Pala

The increasing scientific attention given to precision medicine based on real-world data has led many recent studies to clarify the relationships between treatment effects and patient characteristics. However, this is challenging because of…

Methodology · Statistics 2022-06-20 Ke Wan , Kensuke Tanioka , Toshio Shimokawa

Automatically discovering personalized trajectories (i.e., sequential event patterns) from longitudinal EHR data is crucial for enabling precision medicine in clinical research, yet it remains a formidable challenge even for contemporary AI…

Machine Learning · Computer Science 2026-05-28 Jia Li , Yu Hou , Rui Zhang

High predictive performance and ease of use and interpretability are important requirements for the applicability of a computer-aided diagnosis (CAD) to human reading studies. We propose a CAD system specifically designed to be more…

Machine Learning · Statistics 2016-06-28 Cristina Gallego-Ortiz , Anne L. Martel

Interpretability of AI models allows for user safety checks to build trust in these models. In particular, decision trees (DTs) provide a global view on the learned model and clearly outlines the role of the features that are critical to…

Machine Learning · Computer Science 2023-04-13 Hector Kohler , Riad Akrour , Philippe Preux

In precision medicine, Dynamic Treatment Regimes (DTRs) are treatment protocols that adapt over time in response to a patient's observed characteristics. A DTR is a set of decision functions that takes an individual patient's information as…

Methodology · Statistics 2022-03-17 Cong Jiang , Michael Wallace , Mary Thompson

Estimation and evaluation of individualized treatment rules have been studied extensively, but real-world treatment resource constraints have received limited attention in existing methods. We investigate a setting in which treatment is…

Methodology · Statistics 2022-11-24 Hongxiang Qiu , Marco Carone , Alex Luedtke

In several medical decision-making problems, such as antibiotic prescription, laboratory testing can provide precise indications for how a patient will respond to different treatment options. This enables us to "fully observe" all potential…

Machine Learning · Computer Science 2020-08-14 Soorajnath Boominathan , Michael Oberst , Helen Zhou , Sanjat Kanjilal , David Sontag