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Part-prototype models are explainable-by-design image classifiers, and a promising alternative to black box AI. This paper explores the applicability and potential of interpretable machine learning, in particular PIP-Net, for automated…

Computer Vision and Pattern Recognition · Computer Science 2023-09-12 Meike Nauta , Johannes H. Hegeman , Jeroen Geerdink , Jörg Schlötterer , Maurice van Keulen , Christin Seifert

Personalized treatment decisions have become an integral part of modern medicine. Thereby, the aim is to make treatment decisions based on individual patient characteristics. Numerous methods have been developed for learning such policies…

Machine Learning · Statistics 2023-06-27 Daniel Tschernutter , Tobias Hatt , Stefan Feuerriegel

Randomized Controlled Trials (RCTs), or A/B testing, have become the gold standard for optimizing various operational policies on online platforms. However, RCTs on these platforms typically cover a limited number of discrete treatment…

Econometrics · Economics 2026-02-06 Zhiqi Zhang , Zhiyu Zeng , Ruohan Zhan , Dennis Zhang

Public policies and medical interventions often involve dynamic treatment assignments, in which individuals receive a sequence of interventions over multiple stages. We study the statistical learning of optimal dynamic treatment regimes…

Methodology · Statistics 2025-05-21 Shosei Sakaguchi

Estimating personalized effects of treatments is a complex, yet pervasive problem. To tackle it, recent developments in the machine learning (ML) literature on heterogeneous treatment effect estimation gave rise to many sophisticated, but…

Machine Learning · Computer Science 2022-06-17 Jonathan Crabbé , Alicia Curth , Ioana Bica , Mihaela van der Schaar

In precision medicine, deriving the individualized treatment rule (ITR) is crucial for recommending the optimal treatment based on patients' baseline covariates. The covariate-specific treatment effect (CSTE) curve presents a graphical…

Computation · Statistics 2025-08-22 Yi Zhou , Yuhao Deng , Yu-Shi Tian , Peng Wu , Wenjie Hu , Haoxiang Wang , Ewout Steyerberg , Xiao-Hua Zhou

We propose a matching method for observational data that matches units with others in unit-specific, hyper-box-shaped regions of the covariate space. These regions are large enough that many matches are created for each unit and small…

Methodology · Statistics 2020-08-11 Marco Morucci , Vittorio Orlandi , Sudeepa Roy , Cynthia Rudin , Alexander Volfovsky

The development of AI-based methods to analyze radiology reports could lead to significant advances in medical diagnosis, from improving diagnostic accuracy to enhancing efficiency and reducing workload. However, the lack of…

Computation and Language · Computer Science 2025-08-14 Yuyan Ge , Kwan Ho Ryan Chan , Pablo Messina , René Vidal

Machine learning has become omnipresent with applications in various safety-critical domains such as medical, law, and transportation. In these domains, high-stake decisions provided by machine learning necessitate researchers to design…

Machine Learning · Computer Science 2022-09-01 Bishwamittra Ghosh , Dmitry Malioutov , Kuldeep S. Meel

We investigate a long-debated question, which is how to create predictive models of recidivism that are sufficiently accurate, transparent, and interpretable to use for decision-making. This question is complicated as these models are used…

Machine Learning · Statistics 2020-10-20 Jiaming Zeng , Berk Ustun , Cynthia Rudin

Precision medicine seeks to match patients with treatments that produce the greatest benefit. The Predicted Individual Treatment Effect (PITE)-the difference between predicted outcomes under treatment and control-quantifies this benefit but…

Applications · Statistics 2026-02-09 Pamela M. Chiroque-Solano , M Lee Van Horn , Thomas Jaki

Supervised Machine Learning (SML) algorithms such as Gradient Boosting, Random Forest, and Neural Networks have become popular in recent years due to their increased predictive performance over traditional statistical methods. This is…

Machine Learning · Statistics 2018-06-05 Linwei Hu , Jie Chen , Vijayan N. Nair , Agus Sudjianto

When training automated systems, it has been shown to be beneficial to adapt the representation of data by learning a problem-specific metric. This metric is global. We extend this idea and, for the widely used family of k nearest neighbors…

Machine Learning · Computer Science 2021-09-30 Jan Philip Göpfert , Heiko Wersing , Barbara Hammer

This paper proposes a new paradigm for learning a set of independent logical rules in disjunctive normal form as an interpretable model for classification. We consider the problem of learning an interpretable decision rule set as training a…

Machine Learning · Computer Science 2021-03-15 Litao Qiao , Weijia Wang , Bill Lin

Tackling non-IID data is an open challenge in federated learning research. Existing FL methods, including robust FL and personalized FL, are designed to improve model performance without consideration of interpreting non-IID across clients.…

Machine Learning · Computer Science 2024-07-01 Peng Yan , Guodong Long , Jing Jiang , Michael Blumenstein

Inverse reinforcement learning (IRL) for linear systems seeks a cost function whose optimal controller reproduces an expert policy from data. Existing data-driven methods for discrete-time linear systems are largely built on iterative…

Systems and Control · Electrical Eng. & Systems 2026-05-12 Duc Cuong Nguyen , Phuong Nam Dao

Machine learning algorithms often produce models considered as complex black-box models by both end users and developers. They fail to explain the model in terms of the domain they are designed for. The proposed Iterative Visual Logical…

Machine Learning · Computer Science 2021-07-13 Sridevi Narayana Wagle , Boris Kovalerchuk

We propose CHiLL (Crafting High-Level Latents), an approach for natural-language specification of features for linear models. CHiLL prompts LLMs with expert-crafted queries to generate interpretable features from health records. The…

Computation and Language · Computer Science 2023-10-23 Denis Jered McInerney , Geoffrey Young , Jan-Willem van de Meent , Byron C. Wallace

Interpretable policy learning seeks to estimate intelligible decision policies from observed actions; however, existing models force a tradeoff between accuracy and interpretability, limiting data-driven interpretations of human…

Machine Learning · Computer Science 2024-05-09 Jannik Deuschel , Caleb N. Ellington , Yingtao Luo , Benjamin J. Lengerich , Pascal Friederich , Eric P. Xing

The wide-spread adoption of representation learning technologies in clinical decision making strongly emphasizes the need for characterizing model reliability and enabling rigorous introspection of model behavior. While the former need is…

Machine Learning · Computer Science 2020-05-01 Jayaraman J. Thiagarajan , Prasanna Sattigeri , Deepta Rajan , Bindya Venkatesh
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