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The lack of transparency of data-driven Artificial Intelligence techniques limits their interpretability and acceptance into healthcare decision-making processes. We propose an attribution-based approach to improve the interpretability of…

Artificial Intelligence · Computer Science 2025-07-09 Alessandro Umbrico , Guido Bologna , Luca Coraci , Francesca Fracasso , Silvia Gola , Gabriella Cortellessa

Local Interpretable Model-Agnostic Explanations (LIME) is a popular method to perform interpretability of any kind of Machine Learning (ML) model. It explains one ML prediction at a time, by learning a simple linear model around the…

Machine Learning · Computer Science 2022-02-09 Giorgio Visani , Enrico Bagli , Federico Chesani

In recent years, the field of precision medicine has seen many advancements. Significant focus has been placed on creating algorithms to estimate individualized treatment rules (ITR), which map from patient covariates to the space of…

Methodology · Statistics 2021-12-09 Kushal S. Shah , Haoda Fu , Michael R. Kosorok

In the field of high-performance computing (HPC), there has been recent exploration into the use of deep reinforcement learning for cluster scheduling (DRL scheduling), which has demonstrated promising outcomes. However, a significant…

Machine Learning · Computer Science 2024-03-26 Boyang Li , Zhiling Lan , Michael E. Papka

Most of the work on interpretable machine learning has focused on designing either inherently interpretable models, which typically trade-off accuracy for interpretability, or post-hoc explanation systems, which lack guarantees about their…

Machine Learning · Computer Science 2019-06-05 Gregory Plumb , Maruan Al-Shedivat , Eric Xing , Ameet Talwalkar

An optimal dynamic treatment regime (DTR) is a sequence of decision rules aimed at providing the best course of treatments individualized to patients. While conventional DTR estimation uses longitudinal data, such data can also be…

Methodology · Statistics 2025-02-06 Larry Dong , Eleanor Pullenayegum , Rodolphe Thiébaut , Olli Saarela

Interpretable machine learning (IML) becomes increasingly important in highly regulated industry sectors related to the health and safety or fundamental rights of human beings. In general, the inherently IML models should be adopted because…

Machine Learning · Computer Science 2021-11-03 Agus Sudjianto , Aijun Zhang

Interpretable machine learning offers insights into what factors drive a certain prediction of a black-box system. A large number of interpreting methods focus on identifying explanatory input features, which generally fall into two main…

Machine Learning · Computer Science 2023-06-02 Vy Vo , Van Nguyen , Trung Le , Quan Hung Tran , Gholamreza Haffari , Seyit Camtepe , Dinh Phung

Interpretable deep learning is a fundamental building block towards safer AI, especially when the deployment possibilities of deep learning-based computer-aided medical diagnostic systems are so eminent. However, without a computational…

Machine Learning · Computer Science 2018-06-27 Anirban Mukhopadhyay

Explainable Artificial Intelligence (XAI) methods, such as Local Interpretable Model-Agnostic Explanations (LIME), have advanced the interpretability of black-box machine learning models by approximating their behavior locally using…

Artificial Intelligence · Computer Science 2025-08-22 Rehan Raza , Guanjin Wang , Kok Wai Wong , Hamid Laga , Marco Fisichella

Because different patients may response quite differently to the same drug or treatment, there is increasing interest in discovering individualized treatment rule. In particular, people are eager to find the optimal individualized treatment…

Methodology · Statistics 2016-04-14 Wei Xiao , Hao Helen Zhang , Wenbin Lu

Data-driven pricing strategies are becoming increasingly common, where customers are offered a personalized price based on features that are predictive of their valuation of a product. It is desirable for this pricing policy to be simple…

Machine Learning · Statistics 2021-06-11 Max Biggs , Wei Sun , Markus Ettl

Recent advancements in artificial intelligence (AI) have facilitated its widespread adoption in primary medical services, addressing the demand-supply imbalance in healthcare. Vision Transformers (ViT) have emerged as state-of-the-art…

Computer Vision and Pattern Recognition · Computer Science 2023-09-04 Tin Lai

In randomized trials involving multiple treatments, bivariate survival outcomes present significant analytical challenges for making decisions. This paper addresses the problem of deriving optimal individualized treatment rules to maximize…

Machine Learning · Statistics 2026-05-29 Kun Ren , Yifan Cui , Wen Su

We propose a scalable computerized approach for large-scale inference of Liver Imaging Reporting and Data System (LI-RADS) final assessment categories in narrative ultrasound (US) reports. Although our model was trained on reports created…

Computation and Language · Computer Science 2018-06-20 Imon Banerjee , Hailey H. Choi , Terry Desser , Daniel L. Rubin

In causal inference, estimating heterogeneous treatment effects (HTE) is critical for identifying how different subgroups respond to interventions, with broad applications in fields such as precision medicine and personalized advertising.…

Machine Learning · Computer Science 2024-07-02 Jiehui Zhou , Linxiao Yang , Xingyu Liu , Xinyue Gu , Liang Sun , Wei Chen

As artificial intelligence (AI) systems become increasingly integrated into critical decision-making processes, the need for transparent and interpretable models has become paramount. In this article we present a new ruleset creation method…

Machine Learning · Computer Science 2024-07-30 Mario Parrón Verdasco , Esteban García-Cuesta

Image-Text Retrieval (ITR) finds broad applications in healthcare, aiding clinicians and radiologists by automatically retrieving relevant patient cases in the database given the query image and/or report, for more efficient clinical…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Meng Zheng , Jiajin Zhang , Benjamin Planche , Zhongpai Gao , Terrence Chen , Ziyan Wu

Interpretability of deep learning is widely used to evaluate the reliability of medical imaging models and reduce the risks of inaccurate patient recommendations. For models exceeding human performance, e.g. predicting RNA structure from…

Quantitative Methods · Quantitative Biology 2022-08-31 Mara Graziani , Niccolò Marini , Nicolas Deutschmann , Nikita Janakarajan , Henning Müller , María Rodríguez Martínez

Decision-making processes in healthcare can be highly complex and challenging. Machine Learning tools offer significant potential to assist in these processes. However, many current methodologies rely on complex models that are not easily…

Artificial Intelligence · Computer Science 2025-03-24 Alessio Cascione , Mattia Setzu , Federico A. Galatolo , Mario G. C. A. Cimino , Riccardo Guidotti