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Learning on small data is a challenge frequently encountered in many real-world applications. In this work we study how effective quantum ensemble models are when trained on small data problems in healthcare and life sciences. We…

Since classical machine learning has become a powerful tool for developing data-driven algorithms, quantum machine learning is expected to similarly impact the development of quantum algorithms. The literature reflects a mutually beneficial…

Quantum Physics · Physics 2024-12-13 Leandro C. Souza , Bruno C. Guingo , Gilson Giraldi , Renato Portugal

This article presents a quantum computing approach to designing of similarity measures and kernels for classification of stochastic symbolic time series. In the area of machine learning, kernels are important components of various…

Quantum Physics · Physics 2025-06-10 Vanio Markov , Vladimir Rastunkov , Daniel Fry

With near-term quantum devices available and the race for fault-tolerant quantum computers in full swing, researchers became interested in the question of what happens if we replace a supervised machine learning model with a quantum…

Quantum Physics · Physics 2021-04-20 Maria Schuld

We compare the performance of randomized classical and quantum neural networks (NNs) as well as classical and quantum-classical hybrid convolutional neural networks (CNNs) for the task of supervised binary image classification. We keep the…

Quantum Physics · Physics 2025-11-24 Daniel Basilewitsch , João F. Bravo , Christian Tutschku , Frederick Struckmeier

Single-cell RNA sequencing (scRNA-seq) has revolutionized our ability to analyze gene expression at the resolution of individual cells, providing unprecedented insights into cellular heterogeneity and complex biological systems. This paper…

Other Quantitative Biology · Quantitative Biology 2024-06-11 Megha Patel , Nimish Magre , Himanshi Motwani , Nik Bear Brown

It is one of the most fundamental objectives in quantum information science to understand the boundary between the computational power of classical and quantum computers. One possible avenue to explore this boundary is to identify classes…

Quantum Physics · Physics 2025-03-28 Christophe Piveteau

Due to the linearity of quantum mechanics, it remains a challenge to design quantum generative machine learning models that embed non-linear activations into the evolution of the statevector. However, some of the most successful classical…

Quantum Physics · Physics 2023-01-18 Kaitlin Gili , Mykolas Sveistrys , Chris Ballance

Quantum repeaters are essential for scalable long-distance quantum networking. As quantum information processing moves toward fault-tolerant and error-corrected operations, it becomes increasingly important to study quantum repeaters that…

Quantum Physics · Physics 2026-05-11 Sagar Patange , Caitao Zhan , Bikun Li , Joaquin Chung , Allen Zang , Liang Jiang , Rajkumar Kettimuthu

Cell populations are never truly homogeneous; individual cells exist in biochemical states that define functional differences between them. New technology based on microfluidic arrays combined with multiplexed quantitative polymerase chain…

Quantum Kernel Estimation (QKE) is a technique based on leveraging a quantum computer to estimate a kernel function that is classically difficult to calculate, which is then used by a classical computer for training a Support Vector Machine…

Quantum Physics · Physics 2023-08-01 Marco Russo , Edoardo Giusto , Bartolomeo Montrucchio

Quantum-like modeling (QLM) - quantum theory applications outside of physics - are intensively developed with applications in biology, cognition, psychology, and decision-making. For cognition, QLM should be distinguished from quantum…

Neurons and Cognition · Quantitative Biology 2025-12-16 Andrei Khrennikov , Makiko Yamada

Single-cell RNA-sequencing (scRNA-seq) has become a routinely used technique to quantify the gene expression profile of thousands of single cells simultaneously. Analysis of scRNA-seq data plays an important role in the study of cell states…

Genomics · Quantitative Biology 2022-10-13 Matthew Brendel , Chang Su , Zilong Bai , Hao Zhang , Olivier Elemento , Fei Wang

Quantum kernel methods are a promising branch of quantum machine learning, yet their effectiveness on diverse, high-dimensional, real-world data remains unverified. Current research has largely been limited to low-dimensional or synthetic…

Machine Learning · Computer Science 2026-02-19 Jiang Yuhan , Matthew Otten

Single cell combinatorial indexing RNA sequencing (sci-RNA-seq) is a powerful method for recovering gene expression data from an exponentially scalable number of individual cells or nuclei. However, sci-RNA-seq is a complex protocol that…

Comparisons of single-cell RNA sequencing (scRNA-seq) data across species can reveal links between cellular gene expression and the evolution of cell functions, features, and phenotypes. These comparisons invoke evolutionary histories, as…

Populations and Evolution · Quantitative Biology 2023-07-07 Samuel H. Church , Jasmine L. Mah , Casey W. Dunn

Recent advances in single-cell technologies have advanced our understanding of gene regulation and cellular heterogeneity at single-cell resolution. Single-cell data contain both gene expression levels and the proportion of expressing…

Methodology · Statistics 2026-04-10 Seungjun Ahn , Donald Porchia , Panos Roussos , Maaike van Gerwen , Qing Lu , Zhigang Li

Quantum computers have the opportunity to be transformative for a variety of computational tasks. Recently, there have been proposals to use the unsimulatably of large quantum devices to perform regression, classification, and other machine…

Results from global sensitivity analysis (GSA) often guide the understanding of complicated input-output systems. Kernel-based GSA methods have recently been proposed for their capability of treating a broad scope of complex systems. In…

Methodology · Statistics 2022-08-09 John Barr , Herschel Rabitz

Recently, with the digitalization of medicine, the utilization of real-world medical data collected from clinical sites has been attracting attention. In this study, quantum computing was applied to a linear non-Gaussian acyclic model to…

Quantum Physics · Physics 2023-04-07 Hideaki Kawaguchi