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Screening patients for clinical trial eligibility remains a manual, time-consuming, and resource-intensive process. We present a secure, scalable proof-of-concept system for Artificial Intelligence (AI)-augmented patient-trial matching that…

Accurate symptom-to-disease classification and clinically grounded treatment recommendations remain challenging, particularly in heterogeneous patient settings with high diagnostic risk. Existing large language model (LLM)-based systems…

Large language models (LLMs) have shown impressive potential in helping with numerous medical challenges. Deploying LLMs in high-stakes applications such as medicine, however, brings in many concerns. One major area of concern relates to…

Computation and Language · Computer Science 2025-04-15 Hamed Fayyaz , Raphael Poulain , Rahmatollah Beheshti

Medical Dialogue Generation serves a critical role in telemedicine by facilitating the dissemination of medical expertise to patients. Existing studies focus on incorporating textual representations, which have limited their ability to…

Computation and Language · Computer Science 2023-09-20 Bohao Yang , Chen Tang , Chenghua Lin

Synthetic data generation is an important application of machine learning in the field of medical imaging. While existing approaches have successfully applied fine-tuned diffusion models for synthesizing medical images, we explore potential…

Computer Vision and Pattern Recognition · Computer Science 2024-10-04 Lakshmi Nair

Dementia is under-recognized in the community, under-diagnosed by healthcare professionals, and under-coded in claims data. Information on cognitive dysfunction, however, is often found in unstructured clinician notes within medical records…

Each year, hundreds of clinical trials are conducted to evaluate new medical interventions, but sharing patient records from these trials with other institutions can be challenging due to privacy concerns and federal regulations. To help…

Machine Learning · Computer Science 2025-02-19 Trisha Das , Zifeng Wang , Afrah Shafquat , Mandis Beigi , Jason Mezey , Jacob Aptekar , Jimeng Sun

Due to privacy issues and limited amount of publicly available labeled datasets in the domain of medical imaging, we propose an image generation pipeline to synthesize 3D echocardiographic images with corresponding ground truth labels, to…

Image and Video Processing · Electrical Eng. & Systems 2024-03-11 Cristiana Tiago , Andrew Gilbert , Ahmed S. Beela , Svein Arne Aase , Sten Roar Snare , Jurica Sprem

Preservation of private user data is of paramount importance for high Quality of Experience (QoE) and acceptability, particularly with services treating sensitive data, such as IT-based health services. Whereas anonymization techniques were…

Machine Learning · Computer Science 2024-03-04 Navid Ashrafi , Vera Schmitt , Robert P. Spang , Sebastian Möller , Jan-Niklas Voigt-Antons

Amyotrophic Lateral Sclerosis (ALS) is a rare neurodegenerative disease, and high-quality EEG data from ALS patients are scarce. This data scarcity, coupled with severe class imbalance between ALS and healthy control recordings, poses a…

Machine Learning · Computer Science 2025-06-23 Abdulvahap Mutlu , Şengül Doğan , Türker Tuncer

The recent surge in research focused on generating synthetic data from large language models (LLMs), especially for scenarios with limited data availability, marks a notable shift in Generative Artificial Intelligence (AI). Their ability to…

Machine Learning · Computer Science 2024-03-08 Xu Guo , Yiqiang Chen

It is well-established that more data generally improves AI model performance. However, data collection can be challenging for certain tasks due to the rarity of occurrences or high costs. These challenges are evident in our use case, where…

Computer Vision and Pattern Recognition · Computer Science 2025-09-17 Martin Thißen , Thi Ngoc Diep Tran , Barbara Esteve Ratsch , Ben Joel Schönbein , Ute Trapp , Beate Egner , Romana Piat , Elke Hergenröther

Speech Emotion Recognition models typically use single categorical labels, overlooking the inherent ambiguity of human emotions. Ambiguous Emotion Recognition addresses this by representing emotions as probability distributions, but…

Audio and Speech Processing · Electrical Eng. & Systems 2026-01-22 Wenda Zhang , Hongyu Jin , Siyi Wang , Zhiqiang Wei , Ting Dang

Real world collection of Activities of Daily Living data is challenging due to privacy concerns, costly deployment and labeling, and the inherent sparsity and imbalance of human behavior. We present ADLGen, a generative framework…

Machine Learning · Computer Science 2025-05-26 Weihang You , Hanqi Jiang , Zishuai Liu , Zihang Xie , Tianming Liu , Jin Lu , Fei Dou

Synthesizing clinical evidence largely relies on systematic reviews of clinical trials and retrospective analyses from medical literature. However, the rapid expansion of publications presents challenges in efficiently identifying,…

Computation and Language · Computer Science 2024-10-30 Zifeng Wang , Lang Cao , Benjamin Danek , Qiao Jin , Zhiyong Lu , Jimeng Sun

In the field of emotion recognition, the development of high-performance models remains a challenge due to the scarcity of high-quality, diverse emotional datasets. Emotional expressions are inherently subjective, shaped by individual…

Computation and Language · Computer Science 2025-09-16 Keito Inoshita , Rushia Harada

Class imbalance can often degrade predictive performance of supervised learning algorithms. Balanced classes can be obtained by oversampling exact copies, with noise, or interpolation between nearest neighbours (as in traditional SMOTE…

Machine Learning · Computer Science 2022-01-17 Emily Muller , Xu Zheng , Jer Hayes

Language models trained on large-scale corpus often generate content that is harmful, toxic, or contrary to human preferences, making their alignment with human values a critical concern. Reinforcement learning from human feedback (RLHF)…

Computation and Language · Computer Science 2023-10-26 Jixiang Hong , Quan Tu , Changyu Chen , Xing Gao , Ji Zhang , Rui Yan

Existing Large Language Model (LLM) approaches to SystemVerilog Assertion (SVA) generation primarily focus on syntactic validity and formal verification outcomes, while semantic alignment between generated assertions and natural language…

Artificial Intelligence · Computer Science 2026-05-26 Jaime Rafael Imperial , Hao Zheng

This paper quantitatively reveals the state-of-the-art and state-of-the-practice AI systems only achieve acceptable performance on the stringent conditions that all categories of subjects are known, which we call closed clinical settings,…