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Reliable early detection of Alzheimer's disease (AD) is challenging, particularly due to limited availability of labeled data. While large language models (LLMs) have shown strong transfer capabilities across domains, adapting them to the…

Computation and Language · Computer Science 2026-02-13 Lei Jiang , Yue Zhou , Natalie Parde

$\textbf{Background:}$ At the onset of a pandemic, such as COVID-19, data with proper labeling/attributes corresponding to the new disease might be unavailable or sparse. Machine Learning (ML) models trained with the available data, which…

This work delves into the expanding role of large language models (LLMs) in generating artificial data. LLMs are increasingly employed to create a variety of outputs, including annotations, preferences, instruction prompts, simulated…

Recent advances in Large Language Models (LLMs) have led to remarkable progresses in medical consultation. However, existing medical LLMs overlook the essential role of Electronic Health Records (EHR) and focus primarily on diagnosis…

Artificial Intelligence · Computer Science 2025-06-26 Weijieying Ren , Tianxiang Zhao , Lei Wang , Tianchun Wang , Vasant Honavar

Longitudinal patient data has the potential to improve clinical risk stratification models for disease. However, chronic diseases that progress slowly over time are often heterogeneous in their clinical presentation. Patients may progress…

Machine Learning · Computer Science 2018-03-05 Dev Goyal , Zeeshan Syed , Jenna Wiens

This paper presents a proof-of-concept digital twin framework for simulation-driven diabetes modeling using benchmark clinical data, synthetic temporal augmentation, and illustrative continuous glucose monitoring (CGM) analysis. Unlike…

Machine Learning · Computer Science 2026-05-13 Zarrin Monirzadeh

Question Answering (QA) datasets have been instrumental in developing and evaluating Large Language Model (LLM) capabilities. However, such datasets are scarce for languages other than English due to the cost and difficulties of collection…

Computation and Language · Computer Science 2024-09-18 Gayane Ghazaryan , Erik Arakelyan , Pasquale Minervini , Isabelle Augenstein

Recent advances in generative models, including large language models (LLMs), vision language models (VLMs), and diffusion models, have accelerated the field of natural language and image processing in medicine and marked a significant…

The rapid advancements in Large Language Models (LLMs) and Vision-Language Models (VLMs) have shown great potential in medical diagnostics, particularly in radiology, where datasets such as X-rays are paired with human-generated diagnostic…

Artificial Intelligence · Computer Science 2024-11-13 Francesco Chiumento , Mingming Liu

The scarcity of domain-specific dialogue datasets limits the development of dialogue systems across applications. Existing research is constrained by general or niche datasets that lack sufficient scale for training dialogue systems. To…

Computation and Language · Computer Science 2025-02-11 Sathya Krishnan Suresh , Wu Mengjun , Tushar Pranav , Eng Siong Chng

Automatic Speech Recognition (ASR) systems are pivotal in transcribing speech into text, yet the errors they introduce can significantly degrade the performance of downstream tasks like summarization. This issue is particularly pronounced…

Alignment techniques have become central to ensuring that Large Language Models (LLMs) generate outputs consistent with human values. However, existing alignment paradigms often model an averaged or monolithic preference, failing to account…

Computation and Language · Computer Science 2025-06-03 Anudeex Shetty , Amin Beheshti , Mark Dras , Usman Naseem

The causal relationships between biomarkers are essential for disease diagnosis and medical treatment planning. One notable application is Alzheimer's disease (AD) diagnosis, where certain biomarkers may influence the presence of others,…

Information Retrieval · Computer Science 2025-06-13 Xiaofan Zhou , Liangjie Huang , Pinyang Cheng , Wenpen Yin , Rui Zhang , Wenrui Hao , Lu Cheng

Clinical language models are important for many applications in healthcare, but their development depends on access to extensive clinical text for pretraining. However, obtaining clinical notes from electronic health records (EHRs) at scale…

Computation and Language · Computer Science 2024-12-02 Jinghui Liu , Anthony Nguyen

The rise of large language models (LLMs) has transformed healthcare by offering clinical guidance, yet their direct deployment to patients poses safety risks due to limited domain expertise. To mitigate this, we propose repositioning LLMs…

Computation and Language · Computer Science 2025-10-14 Wenya Xie , Qingying Xiao , Yu Zheng , Xidong Wang , Junying Chen , Ke Ji , Anningzhe Gao , Prayag Tiwari , Xiang Wan , Feng Jiang , Benyou Wang

Over the last three to five years, it has become possible to generate machine learning synthetic data for healthcare-related uses. However, concerns have been raised about potential negative factors associated with the possibilities of…

This study applies Large Language Models (LLMs) to two foundational Electronic Health Record (EHR) data science tasks: structured data querying (using programmatic languages, Python/Pandas) and information extraction from unstructured…

Computation and Language · Computer Science 2026-01-29 Juan Jose Rubio Jan , Jack Wu , Julia Ive

The rise of AI-generated images (AIGIs) poses growing challenges for digital authenticity, prompting the need for efficient, generalizable image forgery detection systems. Existing methods, whether non-LLM-based or LLM-based, exhibit…

Computer Vision and Pattern Recognition · Computer Science 2026-05-18 Qing Huang , Zhipei Xu , Xuanyu Zhang , Xiangyu Yu , Jian Zhang

The application of large language models (LLMs) in clinical decision support faces significant challenges of "tunnel vision" and diagnostic hallucinations present in their processing unstructured electronic health records (EHRs). To address…

Artificial Intelligence · Computer Science 2026-04-28 Zhiqi Lv , Duofan Tu , Jun Li , Mingyue Zhao , Heqin Zhu , Wenliang Li , Shaohua Kevin Zhou

The rise of In-Context Learning (ICL) for universal medical image segmentation has introduced an unprecedented demand for large-scale, diverse datasets for training, exacerbating the long-standing problem of data scarcity. While data…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Jiesi Hu , Yanwu Yang , Zhiyu Ye , Chenfei Ye , Hanyang Peng , Jianfeng Cao , Ting Ma