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Medical conversations offer insights into clinical communication often absent from Electronic Health Records. However, developing reliable clinical Natural Language Processing (NLP) models is hampered by the scarcity of domain-specific…

Computation and Language · Computer Science 2026-04-14 Cecilia Kuan , Aditya Kamlesh Parikh , Henk van den Heuvel

We present SynthTextEval, a toolkit for conducting comprehensive evaluations of synthetic text. The fluency of large language model (LLM) outputs has made synthetic text potentially viable for numerous applications, such as reducing the…

Computation and Language · Computer Science 2025-11-04 Krithika Ramesh , Daniel Smolyak , Zihao Zhao , Nupoor Gandhi , Ritu Agarwal , Margrét Bjarnadóttir , Anjalie Field

Clinical Decision Support Systems (CDSSs) provide reasoning and inquiry guidance for physicians, yet they face notable challenges, including high maintenance costs and low generalization capability. Recently, Large Language Models (LLMs)…

Computation and Language · Computer Science 2026-04-24 Yue Guo , Fanfu Wang , Jianwei Lv , Xincheng Shi , Yuchen Li , Youya Wang , Yunsheng Zeng , Yujing Liu , Yunhao Qiao , Gen Li , Junfeng Wang , Bo Yuan

Large language models (LLMs) have emerged as powerful tools for medical information retrieval, yet their accuracy and depth remain limited in specialized domains such as Alzheimer's disease (AD), a growing global health challenge. To…

Large Language Models (LLMs) have democratized synthetic data generation, which in turn has the potential to simplify and broaden a wide gamut of NLP tasks. Here, we tackle a pervasive problem in synthetic data generation: its generative…

Computation and Language · Computer Science 2023-05-25 Veniamin Veselovsky , Manoel Horta Ribeiro , Akhil Arora , Martin Josifoski , Ashton Anderson , Robert West

Artificial intelligence systems, particularly large language models (LLMs), are increasingly being employed in high-stakes decisions that impact both individuals and society at large, often without adequate safeguards to ensure safety,…

Artificial Intelligence · Computer Science 2024-06-24 N. Zöller , J. Berger , I. Lin , N. Fu , J. Komarneni , G. Barabucci , K. Laskowski , V. Shia , B. Harack , E. A. Chu , V. Trianni , R. H. J. M. Kurvers , S. M. Herzog

Large language models (LLMs) can generate or synthesize clinical text for a wide range of applications, from improving clinical documentation to augmenting clinical text analytics. Yet evaluations typically focus on a narrow aspect -- such…

Computation and Language · Computer Science 2026-05-19 Jinghui Liu , Sarvesh Soni , Anthony Nguyen

Medical Large Vision-Language Models (Med-LVLMs) have shown promising results in clinical applications, but often suffer from hallucinated outputs due to misaligned visual understanding. In this work, we identify two fundamental limitations…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Aofei Chang , Ting Wang , Fenglong Ma

Despite recent success in applying large language models (LLMs) to electronic health records (EHR), most systems focus primarily on assessment rather than treatment planning. We identify three critical limitations in current approaches:…

This paper introduces SignAgent, a novel agentic framework that utilises Large Language Models (LLMs) for scalable, linguistically-grounded Sign Language (SL) annotation and dataset curation. Traditional computational methods for SLs often…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Oliver Cory , Ozge Mercanoglu Sincan , Richard Bowden

Patient simulation is essential for developing and evaluating mental health dialogue systems. As most existing approaches rely on snapshot-style prompts with limited profile information, homogeneous behaviors and incoherent disease…

Computation and Language · Computer Science 2026-03-25 Baihan Li , Bingrui Jin , Kunyao Lan , Ming Wang , Mengyue Wu

Efficient patient-doctor interaction is among the key factors for a successful disease diagnosis. During the conversation, the doctor could query complementary diagnostic information, such as the patient's symptoms, previous surgery, and…

Computation and Language · Computer Science 2024-10-08 Xueshen Li , Xinlong Hou , Nirupama Ravi , Ziyi Huang , Yu Gan

Clinical data usually cannot be freely distributed due to their highly confidential nature and this hampers the development of machine learning in the healthcare domain. One way to mitigate this problem is by generating realistic synthetic…

Large language models (LLMs) are capable of producing documents, and retrieval augmented generation (RAG) has shown itself to be a powerful method for improving accuracy without sacrificing fluency. However, not all information can be…

Computation and Language · Computer Science 2024-10-04 Marko Sterbentz , Cameron Barrie , Shubham Shahi , Abhratanu Dutta , Donna Hooshmand , Harper Pack , Kristian J. Hammond

We propose a novel framework for integrating fragmented multi-modal data in Alzheimer's disease (AD) research using large language models (LLMs) and knowledge graphs. While traditional multimodal analysis requires matched patient IDs across…

Machine Learning · Computer Science 2025-08-19 Kanan Kiguchi , Yunhao Tu , Katsuhiro Ajito , Fady Alnajjar , Kazuyuki Murase

The development of robust clinical decision support systems is frequently impeded by the scarcity of high-fidelity, privacy-preserving biomedical data. While Generative Large Language Models (LLMs) offer a promising avenue for synthetic…

Machine Learning · Computer Science 2026-04-03 Arshia Ilaty , Hossein Shirazi , Amir Rahmani , Hajar Homayouni

Fact-checking for health-related content is challenging due to the limited availability of annotated training data. In this study, we propose a synthetic data generation pipeline that leverages large language models (LLMs) to augment…

Artificial Intelligence · Computer Science 2025-08-29 Jingze Zhang , Jiahe Qian , Yiliang Zhou , Yifan Peng

Recent advances in deep generative models have greatly expanded the potential to create realistic synthetic health datasets. These synthetic datasets aim to preserve the characteristics, patterns, and overall scientific conclusions derived…

Machine Learning · Computer Science 2024-07-04 Jennifer A Bartell , Sander Boisen Valentin , Anders Krogh , Henning Langberg , Martin Bøgsted

Deep neural networks have become prevalent in human analysis, boosting the performance of applications, such as biometric recognition, action recognition, as well as person re-identification. However, the performance of such networks scales…

Computer Vision and Pattern Recognition · Computer Science 2022-08-22 Indu Joshi , Marcel Grimmer , Christian Rathgeb , Christoph Busch , Francois Bremond , Antitza Dantcheva

There has been a rapidly growing interest in Automatic Symptom Detection (ASD) and Automatic Diagnosis (AD) systems in the machine learning research literature, aiming to assist doctors in telemedicine services. These systems are designed…

Computation and Language · Computer Science 2022-10-14 Arsene Fansi Tchango , Rishab Goel , Zhi Wen , Julien Martel , Joumana Ghosn
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