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Accurately measuring cell stiffness is challenging due to the invasiveness of traditional methods like atomic force microscopy (AFM) and optical stretching. We introduce a non-invasive off-axis system using holographic imaging and acoustic…

We propose a novel hybrid mode interferometer (HMI) leveraging the interference of hybridized TE-TM modes in a silicon-on-insulator (SOI) waveguide integrated with a GeSe phase change material (PCM) layer. The SOI waveguide's dimensions are…

Optics · Physics 2024-10-28 Ranjeet Dwivedi , Fabio Pavanello , Regis Orobtchouk

Silicon carbide (SiC) is a semiconductor used in quantum information processing, microelectromechanical systems, photonics, power electronics, and harsh environment sensors. However, its high temperature stability, high breakdown voltage,…

Applied Physics · Physics 2024-06-13 Jonathan R. Dietz , Aaron M. Day , Amberly Xie , Evelyn L. Hu

Ultrafast sub-ps THz pulse conveys rich distinctive spectral fingerprints related to the vibrational or rotational modes of biomolecules and can be used to resolve the time-dependent dynamics of the motions. Thus, an efficient platform for…

High-speed signal processing is essential for maximizing data throughput in emerging communication applications, like multiple-input multiple-output (MIMO) systems and radio-frequency (RF) interference cancellation. However, as these…

Although recent advancements in learning-based analog circuit design automation have tackled tasks such as topology generation, device sizing, and layout synthesis, efficient performance evaluation remains a major bottleneck. Traditional…

Machine Learning · Computer Science 2025-11-12 Xiaomeng Yang , Jian Gao , Yanzhi Wang , Xuan Zhang

Acoustic tweezers are gaining increasing attention due to their excellent biological compatibility. Recently, the concept of topology has been expanded from condensed matter physics into acoustics, giving rise to a robust wave manipulation…

Applied Physics · Physics 2021-06-23 Hongqing Dai , Linbo Liu , Baizhan Xia , Dejie Yu

Recent advances in microphysiological systems have underscored the need for novel sensing and monitoring systems specifically designed for three-dimensional (3D) cell culture. In this article, an original architecture of a cell-culture…

We present an indirect signal processing-based measurement method for biological quantities in humans that cannot be directly measured. We develop the method by focusing on estimating hepatic enzyme and drug transporter activity through…

Quantitative Methods · Quantitative Biology 2021-01-01 Yoko Franchetti , Thomas D. Nolin , Franz Franchetti

Organic Electrochemical Transistors are considered today as a key technology to interact with biological medium through their intrinsic ionic-electronic coupling. In this paper, we show how this coupling can be finely tuned (in operando)…

Signal Processing · Electrical Eng. & Systems 2021-08-31 Mahdi Ghazal , Michel Daher Mansour , Corentin Scholaert , Thomas Dargent , Yannick Coffinier , Sebastien Pecqueur , Fabien Alibart

In the intact brain, neural activity can be recorded using sensing electrodes and manipulated using light stimulation. Silicon probes with integrated electrodes and micro-LEDs enable the detection and control of neural activity using a…

Signal Processing · Electrical Eng. & Systems 2022-11-28 Alexander Tarnavsky Eitan , Shirly Someck , Mario Zajac , Eran Socher , Eran Stark

The stochastic simulation of large-scale biochemical reaction networks is of great importance for systems biology since it enables the study of inherently stochastic biological mechanisms at the whole cell scale. Stochastic Simulation…

Molecular Networks · Quantitative Biology 2017-10-30 Elias S. Manolakos , Elias Kouskoumvekakis

The importance of haptic in-sensor computing devices has been increasing. In this study, we successfully fabricated a haptic sensor with a hierarchical structure via the sacrificial template method, using carbon…

Emerging Technologies · Computer Science 2024-06-07 Kouki Kimizuka , Saman Azhari , Shoshi Tokuno , Ahmet Karacali , Yuki Usami , Shuhei Ikemoto , Hakaru Tamukoh , Hirofumi Tanaka

Wireless bioelectronic interfaces are increasingly used to control tissue-engineered biohybrid robotic systems. However, a unifying engineering framework linking device design to system-level control remains underdeveloped. Here, we propose…

Robotics · Computer Science 2026-04-16 Hiroyuki Tetsuka , Minoru Hirano

Bio-inspired hardware holds the promise of low-energy, intelligent and highly adaptable computing systems. Applications span from automatic classification for big data management, through unmanned vehicle control, to control for bio-medical…

Emerging Technologies · Computer Science 2016-07-18 Julie Grollier , Damien Querlioz , Mark D. Stiles

Intelligent assistive technologies are increasingly recognized as critical daily-use enablers for people with disabilities and age-related functional decline. Longitudinal studies, curation of quality datasets, live monitoring in activities…

Systems and Control · Electrical Eng. & Systems 2026-01-21 Maxim Yudayev , Juha Carlon , Diwas Lamsal , Vayalet Stefanova , Benjamin Filtjens

Passive acoustic monitoring has become a key strategy in biodiversity assessment, conservation, and behavioral ecology, especially as Internet-of-Things (IoT) devices enable continuous in situ audio collection at scale. While recent…

Audio and Speech Processing · Electrical Eng. & Systems 2026-02-11 Heitor R. Guimarães , Abhishek Tiwari , Mahsa Abdollahi , Anderson R. Avila , Tiago H. Falk

We present a scheme for on-chip optical transduction of strain and displacement of Graphene-based Nano-Electro-Mechanical Systems (NEMS). A detailed numerical study on the feasibility of three silicon-photonic integrated circuit…

Optics · Physics 2019-04-25 Aneesh Dash , S. K. Selvaraja , A. K. Naik

Untethered miniaturized wireless neural sensor nodes with data transmission and energy harvesting capabilities call for circuit and system-level innovations to enable ultra-low energy deep implants for brain-machine interfaces. Realizing…

Neurons and Cognition · Quantitative Biology 2022-10-21 Baibhab Chatterjee , K Gaurav Kumar , Shulan Xiao , Gourab Barik , Krishna Jayant , Shreyas Sen

At the High Energy Photon Source (HEPS) where up to 90 beamlines can be provided in the future, minimisation of workload for individual beamlines and maximisation of knowledge about one beamline that can be applied to other beamlines is…

Instrumentation and Detectors · Physics 2022-04-29 Yu Liu , Xue-Wei Dong , Gang Li