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We describe via simulation novel optimization algorithms for a Hopfield neural network constructed using manufacturable three-terminal Silicon-Oxide-Nitride-Oxide-Silicon (SONOS) synaptic devices. We first present a computationally-light,…

Materials Science · Physics 2021-04-27 Su-in Yi , Suhas Kumar , R. Stanley Williams

With the growing demands of consumer electronic products, the computational requirements are increasing exponentially. Due to the applications' computational needs, the computer architects are trying to pack as many cores as possible on a…

Hardware Architecture · Computer Science 2021-01-15 Farhad Merchant , Dominik Sisejkovic , Lennart M. Reimann , Kirthihan Yasotharan , Thomas Grass , Rainer Leupers

Nanophotonic devices excel at confining light into intense hot spots of the electromagnetic near fields, creating unprecedented opportunities for light-matter coupling and surface-enhanced sensing. Recently, all-dielectric metasurfaces with…

Domain-Specific architectures with accelerators for machine learning and signal processing require efficient bulk data movement and high-bandwidth access to large datasets. Such capabilities are often absent from minimal open-source…

Hardware Architecture · Computer Science 2026-03-16 Philippe Sauter , Thomas Benz , Paul Scheffler , Luca Benini

Scanning ion conductance microscopy (SICM) can image the surface topography of specimens in ionic solutions without mechanical probe--sample contact. This unique capability is advantageous for imaging fragile biological samples but its…

Applied Physics · Physics 2019-12-25 Shinji Watanabe , Satoko Kitazawa , Linhao Sun , Noriyuki Kodera , Toshio Ando

Connected health is a technology that associates medical devices, security devices and communication technologies. It enables patients to be monitored and treated remotely from their home. Patients' data and medical records within a…

Signal Processing · Electrical Eng. & Systems 2018-06-05 Xiaojun Zhai , Amine Ait Si Ali , Abbes Amira , Faycal Bensaali

Introduction: Electrical impedance spectroscopy (EIS) has recently developed as a novel diagnostic device for screening and evaluating cervical dysplasia, prostate cancer, breast cancer and basal cell carcinoma. The current study aimed to…

Quantitative Methods · Quantitative Biology 2024-08-23 Vaibhav Gupta , Poonam Goel , Usha Agrawal , Neena Chaudhary , Garima Jain , Deepak Gupta

Rapid antibiotic susceptibility tests (ASTs) are essential for quick selection of effective drugs to treat bacterial infections at an early stage. However, the most widely used phenotypic ASTs in clinical practice often require 24 - 48…

Instrumentation and Detectors · Physics 2025-08-19 Zheqiang Xu , Victoria C Nolan , Yingtao Yu , Petra Muir , Sanna Koskiniemi , Zhen Zhang

We introduce a novel electro-optomechanic neural sensor for realizing ultra-compact neural recording probes that can detect and relay electrophysiology signals from within neural tissue. This technology addresses outstanding challenges…

The generation of physiologically relevant in-vitro models of biological barriers can play a key role in understanding human diseases and in the development of more predictive methods for assessing toxicity and drug or nutrient absorption.…

Biosignal monitoring, in particular heart activity through heart rate (HR) and heart rate variability (HRV) tracking, is vital in enabling continuous, non-invasive tracking of physiological and cognitive states. Recent studies have explored…

Signal Processing · Electrical Eng. & Systems 2025-05-06 Carlos Santos , Sebastian Frey , Andrea Cossettini , Luca Benini , Victor Kartsch

The recent advancements in bio-engineering and wireless communications systems have motivated researchers to propose novel applications for telemedicine, therapeutics and human health monitoring. For instance, through wireless medical…

Systems and Control · Electrical Eng. & Systems 2021-05-03 Yevgeni Koucheryavy , Anastasia Yastrebova , Daniel P. Martins , Sasitharan Balasubramaniam

Energy-efficient image acquisition on the edge is crucial for enabling remote sensing applications where the sensor node has weak compute capabilities and must transmit data to a remote server/cloud for processing. To reduce the edge energy…

Computer Vision and Pattern Recognition · Computer Science 2025-04-08 Weikai Lin , Tianrui Ma , Adith Boloor , Yu Feng , Ruofan Xing , Xuan Zhang , Yuhao Zhu

This work proposes lossless and near-lossless compression algorithms for multi-channel biomedical signals. The algorithms are sequential and efficient, which makes them suitable for low-latency and low-power signal transmission…

Information Theory · Computer Science 2016-05-17 Ignacio Capurro , Federico Lecumberry , Álvaro Martín , Ignacio Ramírez , Eugenio Rovira , Gadiel Seroussi

In this paper, we present BIMS (Biomedical Information Management System). BIMS is a software architecture designed to provide a flexible computational framework to manage the information needs of a wide range of biomedical research…

Software Engineering · Computer Science 2013-03-26 Oscar Mora , Jesús Bisbal

Therapeutic intervention in neurological disorders still relies heavily on pharmacological solutions, while the treatment of patients with drug resistance remains an open challenge. This is particularly true for patients with epilepsy, 30%…

Human-Computer Interaction · Computer Science 2022-10-20 Margherita Ronchini , Yasser Rezaeiyan , Milad Zamani , Gabriella Panuccio , Farshad Moradi

We present a slow control system to gather all relevant environment information necessary to effectively and reliably run an HPC (High Performance Computing) system at a high value over price ratio. The scalable and reliable overall concept…

Other Computer Science · Computer Science 2018-02-05 Peter Bernd Otte , Dalibor Djukanovic

Optical interconnects are the most promising solution to address the data-movement bottleneck in data centers. Silicon microdisks, benefiting from their compact footprint, low energy consumption, and wavelength division multiplexing (WDM)…

Optics · Physics 2025-10-28 Chao Luan , Alex Sludds , Chao Li , Ian Christen , Ryan Hamerly , Dirk Englund

ALDO2 is a multi-function, adjustable, low dropout linear regulator designed in onsemi I3T80 0.35~$\mu$m HV CMOS technology for use in HEP detectors that adopt silicon photomultipliers (SiPMs). The chip features four independent regulators,…

Instrumentation and Detectors · Physics 2022-08-31 Paolo Carniti , Claudio Gotti , Gianluigi Pessina

The advent of edge intelligence and escalating concerns for data privacy protection have sparked a surge of interest in device-cloud collaborative computing. Large-scale device deployments to validate prototype solutions are often…

Distributed, Parallel, and Cluster Computing · Computer Science 2025-04-03 Ruiguang Pei , Junjie Wu , Dan Peng , Min Fang , Jianan Zhang , Zhihui Fu , Jun Wang