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Standard protocols such as the Model Context Protocol (MCP) that allow LLMs to connect to tools have recently boosted "agentic" AI applications, which, powered by LLMs' planning capabilities, promise to solve complex tasks with the access…

Information Retrieval · Computer Science 2026-04-10 Daniel Dobriy , Frederik Bauer , Amr Azzam , Debayan Banerjee , Axel Polleres

The Model Context Protocol (MCP) standardizes how a large-language-model (LLM) agent and an external tool server exchange messages, but not trust: a host reads a server's self-declared tool list and dispatches calls, with no notion of which…

Cryptography and Security · Computer Science 2026-05-26 Alfredo Metere

This paper provides an in-depth technical analysis and implementation methodology of the open-source Agent-to-Agent (A2A) protocol developed by Google and the Model Context Protocol (MCP) introduced by Anthropic. While the evolution of…

Artificial Intelligence · Computer Science 2025-10-03 Cheonsu Jeong

Large Language Models (LLMs) face critical challenges when analyzing security vulnerabilities in real world codebases: token limits prevent loading entire repositories, code embeddings fail to capture inter procedural data flows, and LLMs…

Cryptography and Security · Computer Science 2026-03-27 Ahmed Lekssays

Recent advancements in large language models (LLMs) provide a more effective pathway for upgrading brain-computer interface (BCI) technology in terms of user interaction. The widespread adoption of BCIs in daily application scenarios is…

Human-Computer Interaction · Computer Science 2025-02-19 Jing Jin , Yutao Zhang , Ruitian Xu , Yixin Chen

We present a system that constructs and maintains an up-to-date co-occurrence network of medical concepts based on continuously mining the latest biomedical literature. Users can explore this network visually via a concise online interface…

Information Retrieval · Computer Science 2015-03-20 Alexei Yavlinsky

People are increasingly turning to large language models (LLMs) for complex information tasks like academic research or planning a move to another city. However, while they often require working in a nonlinear manner -- e.g., to arrange…

Human-Computer Interaction · Computer Science 2023-08-31 Sangho Suh , Bryan Min , Srishti Palani , Haijun Xia

Large Language Models (LLMs) demonstrate strong capabilities in solving complex tasks when integrated with external tools. The Model Context Protocol (MCP) has become a standard interface for enabling such tool-based interactions. However,…

Cryptography and Security · Computer Science 2026-01-23 Jiayi Fu , Yuansen Zhang , Yinggui Wang

While Transformer language models (LMs) are state-of-the-art for information extraction, long text introduces computational challenges requiring suboptimal preprocessing steps or alternative model architectures. Sparse attention LMs can…

Computation and Language · Computer Science 2022-12-01 Joel Stremmel , Brian L. Hill , Jeffrey Hertzberg , Jaime Murillo , Llewelyn Allotey , Eran Halperin

The rapid evolution of Large Language Model (LLM)-based autonomous agents is reshaping the digital landscape toward an emerging Agentic Web, where increasingly specialized agents must collaborate to accomplish complex tasks. However,…

Networking and Internet Architecture · Computer Science 2026-02-25 Xiaohang Nie , Zihan Guo , Youliang Chen , Yuanjian Zhou , Weinan Zhang

Large Language Model (LLM) agents increasingly interact with external systems through tool-calling protocols such as the Model Context Protocol (MCP). In prevailing architectures, the agent must reason about every tool invocation in every…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-05 Abhinav Singh Parmar

Large language models (LLMs) have recently demonstrated their potential in clinical applications, providing valuable medical knowledge and advice. For example, a large dialog LLM like ChatGPT has successfully passed part of the US medical…

Computer Vision and Pattern Recognition · Computer Science 2023-02-15 Sheng Wang , Zihao Zhao , Xi Ouyang , Qian Wang , Dinggang Shen

Computer-use agents that combine GUI interaction with structured API calls via the Model Context Protocol (MCP) show promise for automating software tasks. However, existing approaches lack a principled understanding of how agents should…

Artificial Intelligence · Computer Science 2026-04-14 Tiantian He , Yihang Chen , Keyue Jiang , Ka Yiu Lee , Kaiwen Zhou , Kun Shao , Shuai Wang

Addressing the challenge of multimodal data fusion in high-dimensional biomedical informatics, we propose MMCTOP, a MultiModal Clinical-Trial Outcome Prediction framework that integrates heterogeneous biomedical signals spanning (i)…

Machine Learning · Computer Science 2025-12-29 Carolina Aparício , Qi Shi , Bo Wen , Tesfaye Yadete , Qiwei Han

Large Language Model (LLM)-based agents have demonstrated remarkable capabilities in reasoning, planning, and tool usage. The recently proposed Model Context Protocol (MCP) has emerged as a unifying framework for integrating external tools…

Cryptography and Security · Computer Science 2025-12-03 Yuanhe Zhang , Weiliu Wang , Zhenhong Zhou , Kun Wang , Jie Zhang , Li Sun , Yang Liu , Sen Su

The Model Context Protocol (MCP), introduced by Anthropic, provides a standardized framework for artificial intelligence (AI) systems to interact with external data sources and tools in real-time. While MCP offers significant advantages for…

Cryptography and Security · Computer Science 2025-05-06 Vineeth Sai Narajala , Idan Habler

Computer-assisted diagnostic and prognostic systems of the future should be capable of simultaneously processing multimodal data. Multimodal deep learning (MDL), which involves the integration of multiple sources of data, such as images and…

Computer Vision and Pattern Recognition · Computer Science 2023-10-20 Zhaoyi Sun , Mingquan Lin , Qingqing Zhu , Qianqian Xie , Fei Wang , Zhiyong Lu , Yifan Peng

Large Language Models (LLMs) hold immense promise for revolutionizing financial analysis and decision-making, yet their direct application is often hampered by issues of data hallucination and lack of access to real-time, verifiable…

Computational Engineering, Finance, and Science · Computer Science 2025-06-13 Yifan Zeng

Despite the excitement behind biomedical artificial intelligence (AI), access to high-quality, diverse, and large-scale data - the foundation for modern AI systems - is still a bottleneck to unlocking its full potential. To address this…

Large Language Models (LLMs) show promise in biomedicine but lack true causal understanding, relying instead on correlations. This paper envisions causal LLM agents that integrate multimodal data (text, images, genomics, etc.) and perform…

Artificial Intelligence · Computer Science 2025-05-23 Adib Bazgir , Amir Habibdoust Lafmajani , Yuwen Zhang