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Cloud computing offers on-demand, scalable computing and storage, and has become an essential resource for the analyses of big biomedical data. The usual approach to cloud computing requires users to reserve and provision virtual servers.…

Quantitative Methods · Quantitative Biology 2018-08-01 Dimitar Kumanov , Ling-Hong Hung , Wes Lloyd , Ka Yee Yeung

Accurate and reliable search on online healthcare platforms is critical for user safety and service efficacy. Traditional methods, however, often fail to comprehend complex and nuanced user queries, limiting their effectiveness. Large…

Computation and Language · Computer Science 2025-12-04 Chuyue Wang , Jie Feng , Yuxi Wu , Hang Zhang , Zhiguo Fan , Bing Cheng , Wei Lin

Biomedical research yields a wealth of information, much of which is only accessible through the literature. Consequently, literature search is an essential tool for building on prior knowledge in clinical and biomedical research. Although…

Information Retrieval · Computer Science 2024-04-10 Qiao Jin , Robert Leaman , Zhiyong Lu

The recent advances in LLMs bring a strong demand for efficient system support to improve overall serving efficiency. As LLM inference scales towards multiple GPUs and even multiple compute nodes, various coordination patterns, such as…

Distributed, Parallel, and Cluster Computing · Computer Science 2024-12-18 Hongyi Jin , Ruihang Lai , Charlie F. Ruan , Yingcheng Wang , Todd C. Mowry , Xupeng Miao , Zhihao Jia , Tianqi Chen

Model Context Protocol (MCP) has emerged as a standard interface for connecting LLM agents to external tools. Because MCP servers expose privileged operations such as shell execution, network access, and file-system manipulation to…

Cryptography and Security · Computer Science 2026-05-21 Pengyu Sun , Qishu Jin , Enhao Huang , Zifeng Kang , Xin Liu , Dakun Shen , Song Li

Large Language Models (LLMs) are revolutionizing bioinformatics, enabling advanced analysis of DNA, RNA, proteins, and single-cell data. This survey provides a systematic review of recent advancements, focusing on genomic sequence modeling,…

Computation and Language · Computer Science 2026-03-03 Zhenyu Wang , Zikang Wang , Jiyue Jiang , Pengan Chen , Xiangyu Shi , Yu Li

Website Fingerprinting (WFP) uses deep learning models to classify encrypted network traffic to infer visited websites. While historically effective, prior methods fail to generalize to modern web environments. Single-page applications…

Cryptography and Security · Computer Science 2025-09-17 Chuxu Song , Dheekshith Dev Manohar Mekala , Hao Wang , Richard Martin

Modern web scraping struggles with dynamic, interactive websites that require more than static HTML parsing. Current methods are often brittle and require manual customization for each site. To address this, we introduce Webscraper, a…

Artificial Intelligence · Computer Science 2026-04-01 Guan-Lun Huang , Yuh-Jzer Joung

Effective Question Answering (QA) on large biomedical document collections requires effective document retrieval techniques. The latter remains a challenging task due to the domain-specific vocabulary and semantic ambiguity in user queries.…

Information Retrieval · Computer Science 2025-08-19 Zabir Al Nazi , Vagelis Hristidis , Aaron Lawson McLean , Jannat Ara Meem , Md Taukir Azam Chowdhury

Agentic AI systems and Physical or Embodied AI systems have been two key research verticals at the forefront of Artificial Intelligence and Robotics, with Model Context Protocol (MCP) increasingly becoming a key component and enabler of…

MCP standardizes how LLMs interact with external systems, forming the foundation for general agents. However, existing MCP benchmarks remain narrow in scope: they focus on read-heavy tasks or tasks with limited interaction depth, and fail…

The biomedical field relies heavily on concept linking in various areas such as literature mining, graph alignment, information retrieval, question-answering, data, and knowledge integration. Although large language models (LLMs) have made…

Computation and Language · Computer Science 2023-07-04 Qinyong Wang , Zhenxiang Gao , Rong Xu

Large language models (LLMs) are powerful artificial intelligence (AI) tools transforming how research is conducted. However, their use in research has been met with skepticism, due to concerns about hallucinations, biases and potential…

Artificial Intelligence · Computer Science 2025-07-08 Ruian Ke , Ruy M. Ribeiro

Model Context Protocol (MCP) standardizes interface mapping for large language models (LLMs) to access external data and tools, which revolutionizes the paradigm of tool selection and facilitates the rapid expansion of the LLM agent tool…

Cryptography and Security · Computer Science 2025-11-12 Zihan Wang , Rui Zhang , Yu Liu , Wenshu Fan , Wenbo Jiang , Qingchuan Zhao , Hongwei Li , Guowen Xu

Large Language Models (LLMs) have rapidly become important tools in Biomedical and Health Informatics (BHI), enabling new ways to analyze data, treat patients, and conduct research. This study aims to provide a comprehensive overview of LLM…

Digital Libraries · Computer Science 2024-07-30 Huizi Yu , Lizhou Fan , Lingyao Li , Jiayan Zhou , Zihui Ma , Lu Xian , Wenyue Hua , Sijia He , Mingyu Jin , Yongfeng Zhang , Ashvin Gandhi , Xin Ma

Biomedical queries often rely on a deep understanding of specialized knowledge such as gene regulatory mechanisms and pathological processes of diseases. They require detailed analysis of complex physiological processes and effective…

Computation and Language · Computer Science 2026-02-02 Congying Liu , Xingyuan Wei , Peipei Liu , Yiqing Shen , Yanxu Mao , Tiehan Cui

Brain Computer Interface (BCI) technologies have the potential to improve the lives of millions of people around the world, whether through assistive technologies or clinical diagnostic tools. Despite advancements in the field, however, at…

Machine Learning · Computer Science 2023-01-31 Chad Mello , Troy Weingart , Ethan M. Rudd

This paper introduces Tele-LLM-Hub, a user friendly low-code solution for rapid prototyping and deployment of context aware multi-agent (MA) Large Language Model (LLM) systems tailored for 5G and beyond. As telecom wireless networks become…

Networking and Internet Architecture · Computer Science 2025-11-19 Pranshav Gajjar , Cong Shen , Vijay K Shah

True intelligence requires active capability acquisition, yet current LLM agents inject pre-defined tool schemas into prompts, reducing models to passive selectors and falling short of robust general-purpose agency. We introduce MCP-Zero,…

Artificial Intelligence · Computer Science 2025-06-25 Xiang Fei , Xiawu Zheng , Hao Feng

Large language model powered autonomous agents demand robust, standardized protocols to integrate tools, share contextual data, and coordinate tasks across heterogeneous systems. Ad-hoc integrations are difficult to scale, secure, and…

Artificial Intelligence · Computer Science 2025-05-26 Abul Ehtesham , Aditi Singh , Gaurav Kumar Gupta , Saket Kumar