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Large language models (LLMs) have become important tools in solving biological problems, offering improvements in accuracy and adaptability over conventional methods. Several benchmarks have been proposed to evaluate the performance of…

In recent years, Multimodal Large Language Models (MLLM) have achieved notable advancements, demonstrating the feasibility of developing an intelligent biomedical assistant. However, current biomedical MLLMs predominantly focus on…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Xiaoshuang Huang , Lingdong Shen , Jia Liu , Fangxin Shang , Hongxiang Li , Haifeng Huang , Yehui Yang

The convolutional-based methods provide good segmentation performance in the medical image segmentation task. However, those methods have the following challenges when dealing with the edges of the medical images: (1) Previous…

Image and Video Processing · Electrical Eng. & Systems 2022-08-24 Jinkai Lv , Yuyong Hu , Quanshui Fu , Zhiwang Zhang , Yuqiang Hu , Lin Lv , Guoqing Yang , Jinpeng Li , Yi Zhao

LLM-agents are increasingly used to accelerate the progress of scientific research. Yet a persistent bottleneck is data access: agents not only lack readily available tools for retrieval, but also have to work with unstrcutured,…

Many cultural institutions have made large digitized visual collections available online, often under permissible re-use licences. Creating interfaces for exploring and searching these collections is difficult, particularly in the absence…

Computer Vision and Pattern Recognition · Computer Science 2024-11-08 Taylor Arnold , Lauren Tilton

Current research in biology heavily depends on the availability and efficient use of information. In order to build new knowledge, various sources of biological data must often be combined. Semantic Web technologies, which provide a common…

Quantitative Methods · Quantitative Biology 2009-02-19 Claude Pasquier

Medical Decision-Making (MDM) is a multi-faceted process that requires clinicians to assess complex multi-modal patient data patient, often collaboratively. Large Language Models (LLMs) promise to streamline this process by synthesizing…

Machine learning (ML) algorithms are showing a growing trend in helping the scientific communities across different disciplines and institutions to address large and diverse data problems. However, many available ML tools are…

ChatGPT has drawn considerable attention from both the general public and domain experts with its remarkable text generation capabilities. This has subsequently led to the emergence of diverse applications in the field of biomedicine and…

The year 2023 marked a significant surge in the exploration of applying large language model (LLM) chatbots, notably ChatGPT, across various disciplines. We surveyed the applications of ChatGPT in bioinformatics and biomedical informatics…

Other Quantitative Biology · Quantitative Biology 2024-06-13 Jinge Wang , Zien Cheng , Qiuming Yao , Li Liu , Dong Xu , Gangqing Hu

Running language models in the browser presents a unique opportunity to build efficient, private, and portable AI applications, but requires contending with constrained memory availability and heterogeneous hardware targets. To realize this…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-05-21 Reese Levine , Rithik Sharma , Nikhil Jain , Abhijit Ramesh , Zheyuan Chen , Neha Abbas , James Contini , Tyler Sorensen

To complete assignments provided by humans in natural language, robots must interpret commands, generate and answer relevant questions for scene understanding, and manipulate target objects. Real-world deployments often require multiple…

Robotics · Computer Science 2026-02-06 Xiaopan Zhang , Zejin Wang , Zhixu Li , Jianpeng Yao , Jiachen Li

Models such as GPT-4 and Med-PaLM 2 have demonstrated impressive performance on a wide variety of biomedical NLP tasks. However, these models have hundreds of billions of parameters, are computationally expensive to run, require users to…

In the past few decades, the life sciences have experienced an unprecedented accumulation of data, ranging from genomic sequences and proteomic profiles to heavy-content imaging, clinical assays, and commercial biological products for…

Databases · Computer Science 2025-09-22 Rosalia Moreddu

Artificial intelligence has significantly advanced healthcare, particularly through large language models (LLMs) that excel in medical question answering benchmarks. However, their real-world clinical application remains limited due to the…

Computation and Language · Computer Science 2024-07-01 Zhihao Fan , Jialong Tang , Wei Chen , Siyuan Wang , Zhongyu Wei , Jun Xi , Fei Huang , Jingren Zhou

Large Language Models (LLMs) constitute a breakthrough state-of-the-art Artificial Intelligence (AI) technology which is rapidly evolving and promises to aid in medical diagnosis either by assisting doctors or by simulating a doctor's…

Large language model (LLM)-based AI agents extend LLM capabilities by enabling access to tools such as data sources, APIs, search engines, code sandboxes, and even other agents. While this empowers agents to perform complex tasks, LLMs may…

Software Engineering · Computer Science 2026-01-14 Aarya Doshi , Yining Hong , Congying Xu , Eunsuk Kang , Alexandros Kapravelos , Christian Kästner

Tools to explore scientific literature are essential for scientists, especially in biomedicine, where about a million new papers are published every year. Many such tools provide users the ability to search for specific entities (e.g.…

Computation and Language · Computer Science 2021-07-05 Sunil Mohan , Rico Angell , Nick Monath , Andrew McCallum

As large language models (LLMs) demonstrate increasingly powerful reasoning and orchestration capabilities, LLM-based agents are rapidly proliferating for complex data-related tasks. Despite this progress, the current design of how LLMs…

Databases · Computer Science 2025-08-07 Lianggui Weng , Dandan Liu , Rong Zhu , Bolin Ding , Jingren Zhou

Recent advances in artificial intelligence, particularly large language models LLMs, have shown promising capabilities in transforming rare disease research. This survey paper explores the integration of LLMs in the analysis of rare…

Computation and Language · Computer Science 2025-05-26 Valentina Carbonari , Pierangelo Veltri , Pietro Hiram Guzzi
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